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Pomalidomide-PEG4-azide

Product Name
Pomalidomide-PEG4-azide
CAS No.
2271036-47-4
Chemical Name
Pomalidomide-PEG4-azide
Synonyms
Pomalidomide-PEG?-Azide;Pomalidomide-PEG4-azide;Pomalidomide-NH-?PEG4-?azide;4-((14-azido-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;14-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12-tetraoxatetradecanamide, Crosslinker-E3 ligase ligand conjugate, Pomalidomide conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber
CB78054794
Molecular Formula
C23H30N6O8
Formula Weight
518.53
MOL File
2271036-47-4.mol
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Pomalidomide-PEG4-azide Property

storage temp. 
2-8°C
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Hazard and Precautionary Statements (GHS)

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Pomalidomide-PEG4-azide Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-PEG4-Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

storage

Store at -20°C

Pomalidomide-PEG4-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomalidomide-PEG4-azide Suppliers

China 25 United States 2 Global 27
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-400-6206333 18521732826
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Sigma-Aldrich
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Shanghai Chaolan Chemical Technology Center
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840
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psaitong@jm-bio.com
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Xi'an Confluore Biological Technology Co., Ltd.
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+86-156-80926068 +86-15680926068
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1924344760@qq.com
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Jilin Province Woda Biotechnology Co., Ltd.
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13504435624
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Shaanxi borno biotechnology co., LTD
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Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
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Shanghai Kaiwei Chemical Technology Co., Ltd.
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021-58461859 15821823057
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Zhengzhou convergence chemical co., LTD
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Zhengzhou Akem Chemical Co., Ltd
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Shanghai Haohong Pharmaceutical Co., Ltd.
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Hubei Kele Fine Chemical Co., Ltd
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Wuhan Augda Biotechnology Co., Ltd
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Changzhou Bojia Biomedical Technology Co., Ltd.
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Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
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Beijing Solarbio Science & Tecnology Co., Ltd.
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Suzhou Haiben Pharmaceutical Co., Ltd
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Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
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Zhengzhou Allchem Chemical Co., Ltd
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Jilin Chinese Academy of Sciences-yanshen Technology
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Xi‘an Deeptech Biotechnology Co.,LTD
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TargetMol Chemicals Inc.
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Xian confluore Biological Technology Co., Ltd.
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Jilin Chinese Academy of Sciences-yanshen Technology
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View Lastest Price from Pomalidomide-PEG4-azide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Pomalidomide-NH-PEG4-azide 2271036-47-4
Price
US $0.00/mg
Min. Order
100mg
Purity
>95.00%
Supply Ability
100mg
Release date
2024-04-01

2271036-47-4, Pomalidomide-PEG4-azideRelated Search:

Pomalidomide-PEG2-N3 Pomalidomide-PEG2-butyl iodide E3 Ligase Ligand-Linker Conjugates 22 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-PEG4-CO2H E3 Ligase Ligand-Linker Conjugates 1 POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG1-azide Pomalidomide-PEG5-CO2H POMALIDOMIDE-PEG1-CO2H Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG3-N3 Pomalidomide-PEG6-butyl iodide Pomalidomide-NH-PEG2-azide Pomalidomide-NH-PEG6-azide Pomalidomide-NH-PEG1-azide Pomalidomide-NH-PEG5-azide

  • Pomalidomide-PEG4-azide
  • Pomalidomide-NH-?PEG4-?azide
  • 4-((14-azido-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
  • 14-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12-tetraoxatetradecanamide, Crosslinker-E3 ligase ligand conjugate, Pomalidomide conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
  • Pomalidomide-PEG?-Azide
  • 2271036-47-4