BUTEIN

Product Name: BUTEIN
CAS No.: 487-52-5
Chemical Name: BUTEIN
Synonyms: BUTANOL;2',3,4,4'-TETRAHYDROCHALCONE;(2E)-;BUTEIN;CS-5675;BUTEIN(P);CCG208298;BUTEIN(SH);Butein >AC 1NQY7L)
CBNumber: CB8136455
Molecular Formula: C15H12O5
Formula Weight: 272.25
MOL File: 487-52-5.mol

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BUTEIN Property

Melting point:: 216°C
Boiling point:: 560.9±50.0 °C(Predicted)
Density: 1.483±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >50 mg/mL
form: solid
pka: 7.44±0.35(Predicted)
color: yellow
LogP: 2.405 (est)
CAS DataBase Reference: 487-52-5(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
HS Code: 29145090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 72795
Product name: Butein
Purity: analytical standard
Packaging: 10mg
Price: $259
Updated: 2024/03/01

Sigma-Aldrich

Product number: 203987
Product name: Butein - CAS 487-52-5 - Calbiochem
Purity: A cell-permeable, reversible, substrate competitive, plant polyphenol that acts as a specific protein tyrosine kinase inhibitor.
Packaging: 5MG
Price: $272
Updated: 2022/05/15

TCI Chemical

Product number: B3803
Product name: Butein
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $304
Updated: 2024/03/01

TCI Chemical

Product number: B3803
Product name: Butein
Purity: >98.0%(HPLC)
Packaging: 100mg
Price: $138
Updated: 2024/03/01

Cayman Chemical

Product number: 15371
Product name: Butein
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

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BUTEIN Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent

Definition

ChEBI: A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'.

General Description

Butein (2′,3,4,4′-tetrahydroxychalcone) is a chalcone and a flavonoid, that is produced in plants. It is a plant polyphenol and a bioactive constituent, that is extracted from the heartwood of?Dalbergia odorifera, Caragana jubata and?Rhus verniciflua?stokes, and the stem bark of cashews (Semecarpus anacardium).

Biochem/physiol Actions

Butein exhibit several pharmacological activities, such as anti-oxidant and anti-inflammatory activity. It stimulates apoptotic cell death of human cervical cancer cells. It has therapeutic potentials for chronic diseases, including liver tuberculosis, obesity, diabetes and hypertension. Butein can repress migration and invasion of bladder, breast and pancreatic cancer cells.

BUTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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BUTEIN Suppliers

Americas 1 Canada 2 CHINA 186 Europe 1 Germany 3 India 5 Japan 4 Switzerland 2 United Kingdom 5 United States 22 Global 231

BOC Sciences

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EMMX Biotechnology LLC

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Target molecule Corp.

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Aladdin Scientific

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View Lastest Price from BUTEIN manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Butein 487-52-5
Price: US $0.00/MG
Min. Order: 20MG
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-07

Shanghai Standard Technology Co., Ltd.

Product: Butein 487-52-5
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 100 g
Release date: 2020-08-21

Career Henan Chemical Co

Product: Butein 487-52-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

487-52-5, BUTEINRelated Search:

NODAKENETIN viomycin Pterostilbene Butin 4-CHLORO-1-BUTANOL ACETATE 4-(tert-ButoxycarbonylaMino)-1-butanol 4-(2,2,6-TRIMETHYLCYCLOHEXYL)-2-BUTANOL 7,3',4'-TRIHYDROXYFLAVANONE 4-CHLORO-1-BUTANOL 4-(4-NITROPHENYL)-1-BUTANOL 4-METHYLMERCAPTO-2-AMINO-1-BUTANOL Chalcone 4-BROMO-3,3,4,4-TETRAFLUORO-1-BUTANOL 4-AMINO-2-BUTANOL 4-ETHYLAMINO-1-BUTANOL L-Methioninol 1,1,1,3,3,3-HEXAFLUORO-TERT-BUTANOL 4-AMINO-1-BUTANOL

(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one 2',3,4,4'-Tetrahydroxychalcone

BUTEIN(P)

2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-

Butein 2',3,4,4'-Tetrahydroxychalcone

2-[(E)-2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol

2-[(E)-2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol

2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol

2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol

2-[2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol

2-[2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol

2-[2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol

2-[2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol

2-[2-(2-aminophenyl)vinyl]-5-methylquinolin-8-ol

BUTEIN

2',4',3,4-TETRAHYDROXYCHALCONE

2',3,4,4'-TETRAHYDROXYCHALCONE

2',3,4,4'-TETRAHYDROCHALCONE

3,4,2',4'-TETRAHYDROXYCHALCONE

1-(2,4-DIHYDROXYPHENYL)-3-(3,4-DIHYDROXYPHENYL)-2-PROPEN-1-ONE

BUTANOL

1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propene-1-one

(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one

2',3,4,4'-Tetrahydroxy-trans-chalcone

Einecs 207-659-5

BUTEIN(SH)

BUTEIN WITH HPLC

(2E)-

Butein - CAS 487-52-5 - Calbiochem

Butein &gt

Butein Butein

(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one

AC 1NQY7L)

Butein (NSC-652892

CCG208298

CS-5675

PDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,inhibit,cell,SIRT1,Phosphodiesterase (PDE),ERK,PKB,Butein,AKT,HeLa,HER1,p38,HepG2

(2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one

487-52-5

Receptor Tyrosine Kinase Inhibitors

Epidermal Growth Factor Receptor (EGFR) and Src

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Kinase/Phosphatase Biology

Aromatics

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals