ChemicalBook > CAS DataBase List > Quinazoline

Quinazoline

Product Name
Quinazoline
CAS No.
253-82-7
Chemical Name
Quinazoline
Synonyms
PHENMIAZINE;1,3-BENZODIAZINE;5,6-Benzopyrimidine;QUINAZOLINE;Quinazoline 99%;Benzopyrimidine;Quinazoline >Quinazoline ,98%;Benzo[d]pyrimidine;benzo[a]pyrimidine
CBNumber
CB8181293
Molecular Formula
C8H6N2
Formula Weight
130.15
MOL File
253-82-7.mol
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Quinazoline Property

Melting point:
46-48 °C (lit.)
Boiling point:
243 °C (lit.)
Density 
1.2002 (rough estimate)
refractive index 
1.6231 (estimate)
Flash point:
224 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: freely soluble
pka
3.43(at 20℃)
form 
Crystalline Powder, Crystals and/or Chunks
color 
Yellow to beige to brownish
Merck 
14,8053
BRN 
109370
CAS DataBase Reference
253-82-7(CAS DataBase Reference)
NIST Chemistry Reference
Quinazoline(253-82-7)
EPA Substance Registry System
Quinazoline (253-82-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26-23
WGK Germany 
3
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
123323
Product name
Quinazoline
Purity
99%
Packaging
1g
Price
$73.4
Updated
2024/03/01
Sigma-Aldrich
Product number
123323
Product name
Quinazoline
Purity
99%
Packaging
5g
Price
$237
Updated
2024/03/01
TCI Chemical
Product number
Q0055
Product name
Quinazoline
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$120
Updated
2024/03/01
Alfa Aesar
Product number
B24094
Product name
Quinazoline, 98%
Packaging
1g
Price
$36.6
Updated
2021/12/16
Alfa Aesar
Product number
B24094
Product name
Quinazoline, 98%
Packaging
5g
Price
$126
Updated
2021/12/16
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Quinazoline Chemical Properties,Usage,Production

Chemical Properties

Beige to brownish crystalline powder

Uses

Quinazoline was used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

Definition

ChEBI: A mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms.

General Description

Quinazolines has applications in medicinal chemistry due to their antibacterial, antifungal, anticonvulsant, anti-inflammatory and antitumor activities. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

Biochem/physiol Actions

Genotoxicity of quinazoline was established by bacterial SOS Chromotest (Escherichia Coli).

Purification Methods

Purify quinazoline by passage through an activated alumina column in *C6H6 or pet ether (b 40-60o). Distil it under reduced pressure, sublime it under vacuum and crystallise it from pet ether. The picrate has m 188-189o (from MeOH). [Armarego J Appl Chem 11 70 1961, Armarego Quinazolines, Fused Pyrimidines Part I Brown Ed, Wiley-Interscience 1967, Brown Quinazolines Supplement I Taylor Ed, Wiley-Interscience 1996, ISBN 0-471-14565-3; for covalent hydration see Albert & Armarego Adv Heterocycl Chem 4 1 1965, Beilstein 23 H 175, 23 II 177, 23 III/IV 1221.]

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Quinazoline Suppliers

Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
MP Biomedicals, LLC. (Division of Valiant FC Co., Ltd.)
Tel
--
Fax
--
Email
serv@mpbio.com
Country
United States
ProdList
1854
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
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Barath Biosciences, Inc.
Tel
--
Fax
--
Email
barath@barathbiosciences.com
Country
United States
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VWR International, LLC.
Tel
--
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@sargentwelch.com
Country
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Alichem Inc.
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OChem Incorporation
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Country
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Oakwood Products, Inc.
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--
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sales@oakwoodchemical.com
Country
United States
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United States Biological
Tel
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chemicals@usbio.net
Country
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Combi-Blocks Inc.
Tel
--
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SynQuest Laboratories, Inc.
Tel
--
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Riedel-de Haen AG
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TCI America
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Frontier Scientific, Inc.
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Matrix Scientific
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Waterstone Technology, LLC
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AlliChem, LLC
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Ryan Scientific, Inc.
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Country
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Pfaltz & Bauer, Inc.
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Alfa Aesar
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tech@alfa.com
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3B Scientific Corporation
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HONEST JOY HOLDINGS LIMITED
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APAC Pharmaceutical, LLC
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MP Biomedicals, Inc.
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ChemPacific Corporation
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Wilshire Chemical Company Inc.
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View Lastest Price from Quinazoline manufacturers

Career Henan Chemical Co
Product
Quinazoline 253-82-7
Price
US $98.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-08-04

253-82-7, QuinazolineRelated Search:


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