ChemicalBook > CAS DataBase List > 5-Amino-2-fluoropyridine
5-Amino-2-fluoropyridine
- Product Name
- 5-Amino-2-fluoropyridine
- CAS No.
- 1827-27-6
- Chemical Name
- 5-Amino-2-fluoropyridine
- Synonyms
- 6-FLUOROPYRIDIN-3-AMINE;5-Amino-2-fL;6-FLUORO-3-PYRIDINAMINE;2-FLUOROPYRIDIN-5-AMINE;6-Fluoro-3-pyridineamine;3-Amino-6-fluoropyridine;5-AMINO-2-FLUOROPYRIDINE;5-Amine-2-fluoropyridine;2-FLUORO-5-AMINO PYRIDINE;3-PyridinaMine, 6-fluoro-
- CBNumber
- CB8350068
- Molecular Formula
- C5H5FN2
- Formula Weight
- 112.11
- MOL File
- 1827-27-6.mol
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5-Amino-2-fluoropyridine Property
- Melting point:
- 86-87°C
- Boiling point:
- 264.0±20.0 °C(Predicted)
- Density
- 1.257±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 2?+-.0.10(Predicted)
- form
- powder to crystal
- color
- Purple to Dark purple to Dark red
- CAS DataBase Reference
- 1827-27-6(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-41-37/38
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- HS Code
- 29333990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 714593
- Product name
- 5-Amino-2-fluoropyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $72.5
- Updated
- 2025/07/31
TCI Chemical
- Product number
- A2384
- Product name
- 5-Amino-2-fluoropyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $16
- Updated
- 2025/07/31
TRC
- Product number
- A898163
- Product name
- 5-Amino-2-fluoropyridine
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
TRC
- Product number
- A898163
- Product name
- 5-Amino-2-fluoropyridine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 3H30-3-52
- Product name
- 5-Amino-2-fluoropyridine
- Purity
- 97%
- Packaging
- 2g
- Price
- $10
- Updated
- 2021/12/16
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5-Amino-2-fluoropyridine Chemical Properties,Usage,Production
Chemical Properties
Light yellow Cryst
Uses
5-Amino-2-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
456-24-6
1827-27-6
General procedure for the synthesis of 2-fluoro-5-aminopyridine from 2-fluoro-5-nitropyridine: 50 mL of toluene and 50 mmol of 2-fluoro-5-nitropyridine were added to a 100 mL round-bottomed flask, followed by 0.282 g of 5% Pd/C catalyst and 10 mmol of anhydrous sodium sulfate. The reaction system was placed under hydrogen atmosphere, heated and stirred for 15 hours. Upon completion of the reaction, the mixture was cooled to room temperature, the catalyst was removed by filtration and the filtrate was concentrated by rotary evaporation. The resulting crude product was purified by recrystallization and finally dried under vacuum to give 1.6806 g of 2-fluoro-5-aminopyridine solid in 75% yield.
References
[1] Journal of the Chemical Society - Perkin Transactions 1, 1996, # 18, p. 2221 - 2226
[2] Patent: CN103755744, 2016, B. Location in patent: Paragraph 0065; 0066
[3] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 6, p. 1411 - 1416
[4] Patent: US6355636, 2002, B1. Location in patent: Page column 64
[5] Patent: EP1171440, 2004, B1. Location in patent: Page 53
5-Amino-2-fluoropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Amino-2-fluoropyridine manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- 5-Amino-2-fluoropyridine 1827-27-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-03
Shaanxi Dideu Medichem Co. Ltd
- Product
- 5-Amino-2-fluoropyridine 1827-27-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-07
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 5-Amino-2-fluoropyridine 1827-27-6
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-05
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