Elastase

ChemicalBook > CAS DataBase List > Elastase

Product Name: Elastase
CAS No.: 39445-21-1
Chemical Name: Elastase
Synonyms: Elastase;Elastasee;EC 3.4.21.37;EC 3.4.21.36;Elastase, Purified;LYSOSOMAL ELASTASE;ELASTASE, LEUKOCYTE;Elastase USP/EP/BP;PANCREATOPEPTIDASE E;Elastase (pig pancreas)
CBNumber: CB8394260
Molecular Formula: NULL
Formula Weight: 0
MOL File: Mol file

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Elastase Property

RTECS: TS5052000
storage temp.: -20°C
solubility: H₂O: soluble
form: lyophilized powder
color: white
Water Solubility: Soluble in water.

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Safety

Hazard Codes: B,Xn
Risk Statements: 36/37/38-42
Safety Statements: 23-24-26-36/37-22
WGK Germany: 3
F: 3-10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 324682
Product name: Elastase, Porcine Pancreas, High Purity, Crystallized
Packaging: 250u
Price: $173
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324682
Product name: Elastase, Porcine Pancreas, High Purity, Crystallized
Packaging: 1000u
Price: $520
Updated: 2024/03/01

Alfa Aesar

Product number: J61874
Product name: Elastase, porcine pancreas
Packaging: 1g
Price: $1751
Updated: 2023/06/20

Alfa Aesar

Product number: J61753
Product name: Elastase, porcine pancreas aqueous suspension
Packaging: 100mg
Price: $227
Updated: 2023/06/20

Sigma-Aldrich

Product number: E7885
Product name: Elastase from porcine pancreas
Purity: lyophilized powder, suitable for cell culture
Packaging: 1mg
Price: $76.8
Updated: 2024/03/01

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Elastase Chemical Properties,Usage,Production

Uses

Elastase is used in combination with other proteases for protein analysis by mass spectrometry. Elastase, is used in tissue dissociation because elastin is found in highest concentrations in the elastic fibers of connective tissues, elastase is frequently used to dissociate tissues that contain extensive intercellular fiber networks. It is usually used with other enzymes such as collagenase, trypsin, and chymotrypsin, membrane protein solubilization, protein sequence studies.

Uses

Elastase from porcine pancreas has been used in a study to identify a novel bone/calcium metabolism-regulating factor in porcine pancreas. Elastase from porcine pancreas has also been used in a study to investigate the effect of a specific synthetic inhibitor of neutrophil elastase (ONO-5046) on the course of acute hemorrhagic pancreatitis in dogs.

Uses

Elastase from porcine pancreas has been used:

to treat vero cells?to study its effects on syncytium formation
as a positive control in protease assays
as a component in RPMI 1640 to isolate human aortic smooth muscle cells (HASMCs) from the aortic tissue

General Description

Biochem/physiol Actions

Elastase is a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges. The molecular mass is approximately 25.9 kDa. The enzyme is synthesized as an inactive zymogen, proelastase, which is converted to the active form by limited proteolysis at the N-terminal by trypsin. It is a serine protease with broad specificity. It cleaves protein at the carboxyl side of small hydrophobic amino acids such as Ile, Gly, Ala, Ser, Val, and Leu. The enzyme also hydrolyzes amides and esters such as N-Benzoyl-L-alanine methyl ester. The pH optimum is found to be 8.0-8.5. It does not require any activator, but it is inhibited by diisopropyl fluorophosphate, phenylmethanesulfonyl fluoride, α2-macroglobulin, α1-antitrypsin, sulfonyl fluorides and p-dinitrophenyl diethylphosphate and high salt concentrations. It is extensively used in tissue and cell dissociation procedures. Elastase is effective in the isolation of Type II lung cells.

Elastase Preparation Products And Raw materials

Raw materials

Preparation Products

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Elastase Suppliers

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View Lastest Price from Elastase manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: Elastase 39445-21-1
Price: US $100.00-25.00/kgkg
Min. Order: 1kgkg
Purity: 0.99
Supply Ability: 100
Release date: 2023-09-07

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Elastase 39445-21-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98.0%
Supply Ability: 1kg/month
Release date: 2021-08-24

Hebei Guanlang Biotechnology Co., Ltd.

Product: Elastase 39445-21-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2022-09-29

39445-21-1, ElastaseRelated Search:

Trypsin Papain Pepsin Chymotrypsin Proteinase K PROTEASE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) METHYL ISOCYANOACETATE N-BUTYLISOCYANIDE Ethyl isocyanoacetate 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) TERT-BUTYL ISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) Aluminum acetylacetonate Benzyl isocyanide Tosylmethyl isocyanide Cupric acetylacetonate

EC 3.4.21.36

EC 3.4.21.37

ELASTASE, LEUKOCYTE

ELASTASE, NEUTROPHIL, HUMAN

ELASTASE, HUMAN NEUTROPHIL

ELASTASE, HUMAN NEUTROPHILS

Elastase, pancreatic from porcine pancreas, 30 units/mg

Elastase froM porcine pancreas Min. 200 U/Mg lyophil. salt-free

Elastase froM porcine pancreas(Lyophilized)

Elastase from porcine pancreas(Purified)

Elastase from porcine pancreas(Suspension)

Elastase, Porcine Pancreas, High Purity, Crystallized

Elastase, Purified

Elastase(swine pancreas) (9CI)

LEUKOCYTE ELASTASE, HUMAN NEUTROPHILS

LYSOSOMAL ELASTASE

PANCREATOPEPTIDASE E

Elastase from hog pancreas

Elastase, pancreatic from porcine pancreas

Elastase (pig pancreas)

ELASTASE FROM HOG PANCREAS, CRYST. SUSP., 1-2 U/MG*

ELASTASE, PANCREATIC FROM PORCINE*PANCRE AS CELL CUL

ELASTASE TYPE IV FROM PORCINE PANCREAS

ELASTASE FROM HOG PANCREAS, ~3 U/MG

ELASTASE FROM HOG PANCREAS, ~8 U/MG

ELASTASE, PANCREATIC TYPE I FROM*PORCINE PANCREAS

ELASTASE, PANCREATIC TYPE II-A FROM*PORC INE PANCREA

ELASTASE, PANCREATIC TYPE III FROM*PORCI NE PANCREAS

ELASTASE FROM HOG PANCREAS, ~15 U/MG

ElastaseExPigPancreas(Pre-Crystalline)

ElastaseExPigPancreas(FreezeDried)

expigpancreas,freezedried

Elastase (swine pancreas)

ELASTASE, FROM PORCINE PANCREAS

ELASTASEPORCINE PANCREAS (WHITE POWDER) 30-100 UNITS/MG.

Elastase from hog pancreas, Pancreatopeptidase E

Elastase

Elastase from porcine pancreas,Elastase from hog pancreas, Pancreatopeptidase E

Elastase, pancreatic froM porcine pan

Native Porcine Elastase

Elastase from porcine pancreas lyophilized, powder, white, ~8 U/mg

Elastasee

Elastase USP/EP/BP

Elastase, From Porcine Pancreas, >8 U/mg

Elastase (ELA, PPE) ex. Porcine Pancreas, 10U/mg Protein

pancreatic from porcine pancreas

serine,emphysema,240,polypeptide,acid,Inhibitor,inhibit,residues,Elastase from porcine pancreas,amino

39445-21-1

C20H31N4O7Cl

Proteolytic Enzymes and Substrates

Proteolytic Enzymes

Enzymes, Inhibitors, and Substrates

Biochemicals and Reagents

BioChemical