ChemicalBook > CAS DataBase List > Elastase

Elastase

Product Name
Elastase
CAS No.
39445-21-1
Chemical Name
Elastase
Synonyms
Elastase;Elastasee;EC 3.4.21.37;EC 3.4.21.36;Elastase, Purified;LYSOSOMAL ELASTASE;ELASTASE, LEUKOCYTE;Elastase USP/EP/BP;PANCREATOPEPTIDASE E;Elastase (pig pancreas)
CBNumber
CB8394260
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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Elastase Property

RTECS 
TS5052000
storage temp. 
-20°C
solubility 
H2O: soluble
form 
lyophilized powder
color 
white
PH
8
biological source
Porcine pancreas
Water Solubility 
Soluble in water.
Specific Activity
≥4units/mg protein
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Safety

Hazard Codes 
B,Xn
Risk Statements 
36/37/38-42
Safety Statements 
23-24-26-36/37-22
WGK Germany 
3
3-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
324682
Product name
Elastase, Porcine Pancreas, High Purity, Crystallized
Packaging
250u
Price
$177
Updated
2025/07/31
Sigma-Aldrich
Product number
324682
Product name
Elastase, Porcine Pancreas, High Purity, Crystallized
Packaging
1000u
Price
$533
Updated
2025/07/31
Sigma-Aldrich
Product number
E7885
Product name
Elastase from porcine pancreas
Purity
lyophilized powder, suitable for cell culture
Packaging
1mg
Price
$82.6
Updated
2025/07/31
Sigma-Aldrich
Product number
E1250
Product name
Elastase from porcine pancreas
Purity
Type I, ≥4.0 units/mg protein
Packaging
10mg
Price
$69.5
Updated
2025/07/31
Sigma-Aldrich
Product number
E7885
Product name
Elastase from porcine pancreas
Purity
lyophilized powder, suitable for cell culture
Packaging
5mg
Price
$220
Updated
2025/07/31
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Elastase Chemical Properties,Usage,Production

Uses

Elastase is used in combination with other proteases for protein analysis by mass spectrometry. Elastase, is used in tissue dissociation because elastin is found in highest concentrations in the elastic fibers of connective tissues, elastase is frequently used to dissociate tissues that contain extensive intercellular fiber networks. It is usually used with other enzymes such as collagenase, trypsin, and chymotrypsin, membrane protein solubilization, protein sequence studies.

Uses

Elastase from porcine pancreas has been used in a study to identify a novel bone/calcium metabolism-regulating factor in porcine pancreas. Elastase from porcine pancreas has also been used in a study to investigate the effect of a specific synthetic inhibitor of neutrophil elastase (ONO-5046) on the course of acute hemorrhagic pancreatitis in dogs.

Uses

Elastase from porcine pancreas has been used:

  • to treat vero cells?to study its effects on syncytium formation
  • as a positive control in protease assays
  • as a component in RPMI 1640 to isolate human aortic smooth muscle cells (HASMCs) from the aortic tissue

General Description

Elastase is a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges. The molecular mass is approximately 25.9kDa. The enzyme is synthesized as an inactive zymogen, proelastase, which is converted to the active form by limited proteolysis at the N-terminal by trypsin.

Biochem/physiol Actions

Elastase is a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges. The molecular mass is approximately 25.9 kDa. The enzyme is synthesized as an inactive zymogen, proelastase, which is converted to the active form by limited proteolysis at the N-terminal by trypsin. It is a serine protease with broad specificity. It cleaves protein at the carboxyl side of small hydrophobic amino acids such as Ile, Gly, Ala, Ser, Val, and Leu. The enzyme also hydrolyzes amides and esters such as N-Benzoyl-L-alanine methyl ester. The pH optimum is found to be 8.0-8.5. It does not require any activator, but it is inhibited by diisopropyl fluorophosphate, phenylmethanesulfonyl fluoride, α2-macroglobulin, α1-antitrypsin, sulfonyl fluorides and p-dinitrophenyl diethylphosphate and high salt concentrations. It is extensively used in tissue and cell dissociation procedures. Elastase is effective in the isolation of Type II lung cells.

Elastase Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Elastase manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Elastase 39445-21-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-08-24
Hebei Chuanghai Biotechnology Co., Ltd
Product
Elastase 39445-21-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
Hebei Yanxi Chemical Co., Ltd.
Product
Elastase 39445-21-1
Price
US $100.00-25.00/kgkg
Min. Order
1kgkg
Purity
0.99
Supply Ability
100
Release date
2023-09-07

39445-21-1, ElastaseRelated Search:


  • EC 3.4.21.36
  • EC 3.4.21.37
  • ELASTASE, LEUKOCYTE
  • ELASTASE, NEUTROPHIL, HUMAN
  • ELASTASE, HUMAN NEUTROPHIL
  • ELASTASE, HUMAN NEUTROPHILS
  • Elastase, pancreatic from porcine pancreas, 30 units/mg
  • Elastase froM porcine pancreas Min. 200 U/Mg lyophil. salt-free
  • Elastase froM porcine pancreas(Lyophilized)
  • Elastase from porcine pancreas(Purified)
  • Elastase from porcine pancreas(Suspension)
  • Elastase, Porcine Pancreas, High Purity, Crystallized
  • Elastase, Purified
  • Elastase(swine pancreas) (9CI)
  • LEUKOCYTE ELASTASE, HUMAN NEUTROPHILS
  • LYSOSOMAL ELASTASE
  • PANCREATOPEPTIDASE E
  • Elastase from hog pancreas
  • Elastase, pancreatic from porcine pancreas
  • Elastase (pig pancreas)
  • ELASTASE FROM HOG PANCREAS, CRYST. SUSP., 1-2 U/MG*
  • ELASTASE, PANCREATIC FROM PORCINE*PANCRE AS CELL CUL
  • ELASTASE TYPE IV FROM PORCINE PANCREAS
  • ELASTASE FROM HOG PANCREAS, ~3 U/MG
  • ELASTASE FROM HOG PANCREAS, ~8 U/MG
  • ELASTASE, PANCREATIC TYPE I FROM*PORCINE PANCREAS
  • ELASTASE, PANCREATIC TYPE II-A FROM*PORC INE PANCREA
  • ELASTASE, PANCREATIC TYPE III FROM*PORCI NE PANCREAS
  • ELASTASE FROM HOG PANCREAS, ~15 U/MG
  • ElastaseExPigPancreas(Pre-Crystalline)
  • ElastaseExPigPancreas(FreezeDried)
  • expigpancreas,freezedried
  • Elastase (swine pancreas)
  • ELASTASE, FROM PORCINE PANCREAS
  • ELASTASEPORCINE PANCREAS (WHITE POWDER) 30-100 UNITS/MG.
  • Elastase from hog pancreas, Pancreatopeptidase E
  • Elastase
  • Elastase from porcine pancreas,Elastase from hog pancreas, Pancreatopeptidase E
  • Elastase, pancreatic froM porcine pan
  • Native Porcine Elastase
  • Elastase from porcine pancreas lyophilized, powder, white, ~8 U/mg
  • Elastasee
  • Elastase USP/EP/BP
  • Elastase, From Porcine Pancreas, >8 U/mg
  • Elastase (ELA, PPE) ex. Porcine Pancreas, 10U/mg Protein
  • pancreatic from porcine pancreas
  • serine,emphysema,240,polypeptide,acid,Inhibitor,inhibit,residues,Elastase from porcine pancreas,amino
  • Elastase (swine pancreas) Protein
  • Elastase from porcine pancreas min. 200 U/mg protein
  • Elastase, From Porcine Pancreas, sup. 30 U/mg
  • Elastase (pancreatopeptidase E)
  • Elastinase suspension, from porcine
  • 39445-21-1
  • C20H31N4O7Cl
  • Proteolytic Enzymes and Substrates
  • Proteolytic Enzymes
  • Enzymes, Inhibitors, and Substrates
  • Biochemicals and Reagents