5-AMINO-4-CHLOROPYRIMIDINE

Product Name: 5-AMINO-4-CHLOROPYRIMIDINE
CAS No.: 54660-78-5
Chemical Name: 5-AMINO-4-CHLOROPYRIMIDINE
Synonyms: 4-chloropyriMidin-5-aMine;Amino chloropyrimidine;4-Chloro-5-pyrimidinamine;4-Chloro-5-aMinopyriMidine;5-AMINO-4-CHLOROPYRIMIDINE;5-PYRIMIDINAMINE, 4-CHLORO-;4-chloro-pyriMidin-5-ylaMine;5-Amino-4-chloropyrimidine,96%;5-Pyrimidinamine, 4-chloro- (9CI)
CBNumber: CB8398804
Molecular Formula: C4H4ClN3
Formula Weight: 129.55
MOL File: 54660-78-5.mol

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5-AMINO-4-CHLOROPYRIMIDINE Property

Melting point:: 110-116℃
Boiling point:: 253.8±20.0 °C(Predicted)
Density: 1.437±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 1.30±0.16(Predicted)
form: Solid
color: White to pale brown
Sensitive: Air & Light Sensitive

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39
WGK Germany: 3
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 732281
Product name: 5-Amino-4-chloropyrimidine
Purity: 97%
Packaging: 500mg
Price: $32.5
Updated: 2023/06/20

TCI Chemical

Product number: A2937
Product name: 5-Amino-4-chloropyrimidine
Purity: >97.0%(GC)(T)
Packaging: 200mg
Price: $60
Updated: 2025/07/31

TCI Chemical

Product number: A2937
Product name: 5-Amino-4-chloropyrimidine
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $239
Updated: 2025/07/31

TRC

Product number: A617673
Product name: 5-Amino-4-chloropyrimidine
Packaging: 500mg
Price: $90
Updated: 2021/12/16

Usbiological

Product number: 295674
Product name: 4-Chloro-5-aminopyrimidine
Packaging: 500mg
Price: $360
Updated: 2021/12/16

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5-AMINO-4-CHLOROPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

54851-35-3

54660-78-5

General procedure for the synthesis of 5-amino-4-chloropyrimidine from 5-amino-6-chloropyrimidine-4-thiol: The concentrated product of Example 18 (4.3 g, 26 mmol) was dissolved in EtOH (40 mL). Subsequently, NH4OH (4 mL) was added to this solution. Under stirring, an excess of Raney Nickel was added in batches. the reaction mixture was stirred overnight at room temperature and then heated at 80 °C for 2 h. The reaction was carried out at room temperature. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was concentrated. The crude product was purified by silica fast chromatography using EtOAc/hexane as eluent to give 1.6 g (47% yield) of 5-amino-4-chloropyrimidine as a yellow solid.

References

[1] Patent: US2006/13799, 2006, A1. Location in patent: Page/Page column 59
[2] Patent: WO2006/127584, 2006, A1. Location in patent: Page/Page column 61; 89
[3] Patent: WO2007/8563, 2007, A2. Location in patent: Page/Page column 88

5-AMINO-4-CHLOROPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMINO-4-CHLOROPYRIMIDINE Suppliers

Americas 1 China 118 Europe 2 Germany 4 India 2 Japan 1 United Kingdom 4 United States 30 Global 162

SiChuang NanBu Honesty Technology Co., Ltd.

Tel: 0838-5675166 15883665058
Fax: 0838-5675535
Email: nbcxkj@126.com
Country: China
ProdList: 918
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Nanjing Habo Medical Technology Co., Ltd.

Tel: 025-85760892 13376080562
Fax: 025-85766769
Email: sales@habotech.com
Country: China
ProdList: 884
Advantage: 60

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

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View Lastest Price from 5-AMINO-4-CHLOROPYRIMIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-chloropyrimidin-5-amine 54660-78-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-15

Shaanxi Dideu Medichem Co. Ltd

Product: 4-chloropyrimidin-5-amine 54660-78-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-15

Career Henan Chemical Co

Product: 5-AMINO-4-CHLOROPYRIMIDINE 54660-78-5
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-24

54660-78-5, 5-AMINO-4-CHLOROPYRIMIDINERelated Search:

2,4-Dichloro-5-nitropyrimidine 4,6-Dichloro-2-methyl-5-nitropyrimidine 4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE 2,4-Dichloro-6-methyl-5-nitropyrimidine 4,6-Dichloro-5-nitropyrimidine Moxonidine 2,5-Diamino-4,6-dichloropyrimidine 5-Amino-4,6-dichloropyrimidine 5-Amino-4,6-dichloro-2-methylpyrimidine 2,4,6-TRICHLORO-5-NITROPYRIMIDINE 2-AMINO-5-CHLOROPYRIMIDINE-4-CARBOXYLIC ACID 4-Amino-2-chloropyrimidine-5-carboxylic acid 4-Amino-6-chloropyrimidine-5-carboxaldehyde 2-AMINO-5-CHLOROPYRIMIDINE 4-Amino-2-chloropyrimidine-5-carbonitrile ,97%,4-AMINO-2-CHLOROPYRIMIDINE-5-CARBONITRILE,4-AMINO-2-CHLOROPYRIMIDINE-5-CARBOXNITR& 5-Chloropyrimidine-2,4,6-triamine 4-Amino-6-chloro-2-methylpyrimidine 2-CHLORO-4-(N,N-DIMETHYLAMINO)PYRIMIDINE

5-AMINO-4-CHLOROPYRIMIDINE

5-PYRIMIDINAMINE, 4-CHLORO-

5-Pyrimidinamine, 4-chloro- (9CI)

4-chloropyriMidin-5-aMine

4-Chloro-5-aMinopyriMidine

4-chloro-pyriMidin-5-ylaMine

4-Chloro-5-pyrimidinamine

Amino chloropyrimidine

5-Amino-4-chloropyrimidine,96%

54660-78-5

54660-78-9

Heterocycle-Pyrimidine series

PYRIMIDINE