ChemicalBook > CAS DataBase List > 5-Hydroxyindole-2-carboxylic acid

5-Hydroxyindole-2-carboxylic acid

Product Name
5-Hydroxyindole-2-carboxylic acid
CAS No.
21598-06-1
Chemical Name
5-Hydroxyindole-2-carboxylic acid
Synonyms
5-HO-ICA;NSC 117338;5-HYDROXY-2-INDOLECARBOXYLIC ACID;5-HYDROXYINDOLE-2-CARBOXYLIC ACID;5-Hydroxyindole-2-carboxylicacid,97%;5-Hydroxy-2-indolecarboxylic acid 98%;5-HYDROXY-1H-INDOLE-2-CARBOXYLIC ACID;5-Hydroxyindole-2-carboxylic acid 98%;5-Hydroxy-2-indolecarboxylic acid,98%;1H-Indole-2-carboxylic acid, 5-hydroxy-
CBNumber
CB9206982
Molecular Formula
C9H7NO3
Formula Weight
177.16
MOL File
21598-06-1.mol
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5-Hydroxyindole-2-carboxylic acid Property

Melting point:
249 °C (dec.) (lit.)
Boiling point:
309.06°C (rough estimate)
Density 
1.3312 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
Sealed in dry,2-8°C
solubility 
chloroform/ethanol (1:1): soluble50mg/mL, clear to slightly hazy, yellow to brown
form 
Fuming Liquid
pka
4.38±0.30(Predicted)
color 
Clear colorless to slightly yellow
BRN 
153214
CAS DataBase Reference
21598-06-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-21/22
Safety Statements 
26-36-36/37/39
WGK Germany 
3
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
143510
Product name
5-Hydroxyindole-2-carboxylic acid
Purity
98%
Packaging
1g
Price
$105
Updated
2024/03/01
Sigma-Aldrich
Product number
143510
Product name
5-Hydroxyindole-2-carboxylic acid
Purity
98%
Packaging
5g
Price
$177.6
Updated
2024/03/01
Alfa Aesar
Product number
L00786
Product name
5-Hydroxyindole-2-carboxylic acid, 97%
Packaging
1g
Price
$61.65
Updated
2024/03/01
Alfa Aesar
Product number
L00786
Product name
5-Hydroxyindole-2-carboxylic acid, 97%
Packaging
5g
Price
$243
Updated
2024/03/01
Usbiological
Product number
161918
Product name
5-Hydroxyindole-2-carboxylic Acid
Packaging
2.5g
Price
$425
Updated
2021/12/16
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5-Hydroxyindole-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

light yellow to beige crystalline powder

Uses

• ;Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents• ;Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors1• ;Reactant for preparation of melanins as novel nature-inspired radioprotectors2• ;Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity3• ;Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal

Uses

5-Hydroxyindole-2-carboxylic acid was used in HPLC-amperometric detection of serotonin in plasma, platelets and urine.

Uses

A competitive antagonist of potentiation by glycine at the N-methyl-D-aspartate receptors that have been linked to neuronal death, assiciated to such afflictions as stroke and epilepsy.

Definition

ChEBI: 5-Hydroxyindole-2-carboxylic acid is an indolyl carboxylic acid.

General Description

5-Hydroxyindole-2-carboxylic acid on oxidation with KMnO4 yields pyrrole-2,3,5-tricarboxylic acid.

5-Hydroxyindole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Hydroxyindole-2-carboxylic acid Suppliers

Belgium 1 Canada 1 China 90 Europe 2 Germany 5 India 4 Japan 1 Slovakia 1 Switzerland 3 Ukraine 1 United Kingdom 8 United States 25 Global 142
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View Lastest Price from 5-Hydroxyindole-2-carboxylic acid manufacturers

Career Henan Chemical Co
Product
5-Hydroxyindole-2-carboxylic acid 21598-06-1
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg -1000kg
Release date
2020-01-02

21598-06-1, 5-Hydroxyindole-2-carboxylic acidRelated Search:

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  • 21598-06-1
  • C9H7NO3
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • Building Blocks
  • Heterocyclic Building Blocks
  • Building Blocks
  • C7 to C9
  • Chemical Synthesis
  • Heterocyclic Building Blocks
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