DBCO-maleimide

Product Name: DBCO-maleimide
CAS No.: 1395786-30-7
Chemical Name: DBCO-maleimide
Synonyms: Dibenzocyclooctyne-maleimide;DBCO-MAL;DBCO-maleimide;DBCO-Maleimide,Dibenzocyclooctyne-maleimide;DBCO-maleimide (This product is unavailable in the U.S.);DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5);Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.);1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-;N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide;N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
CBNumber: CB92985649
Molecular Formula: C25H21N3O4
Formula Weight: 427.45
MOL File: 1395786-30-7.mol

More

Less

DBCO-maleimide Property

Melting point:: 162 °C
Boiling point:: 790.5±60.0 °C(Predicted)
Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO, DCM, DMF
form: Solid
pka: 15.03±0.46(Predicted)
color: Off-white to Gray

More

Less

Safety

Hazard Codes: N
Risk Statements: 50
Safety Statements: 61

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H400Very toxic to aquatic life
Precautionary statements: P273Avoid release to the environment.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 1MG
Price: $32.8
Updated: 2023/06/20

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 5MG
Price: $101
Updated: 2023/06/20

Sigma-Aldrich

Product number: 760668
Product name: Dibenzocyclooctyne-maleimide
Purity: for Copper-free Click Chemistry
Packaging: 50MG
Price: $393
Updated: 2023/06/20

TRC

Product number: A939575
Product name: Dbco-Maleimide
Packaging: 1mg
Price: $40
Updated: 2021/12/16

Chem-Impex

Product number: 35063
Product name: DBCOmaleimide,95%(HPLC)
Purity: 95%(HPLC)
Packaging: 5MG
Price: $56
Updated: 2021/12/16

More

Less

DBCO-maleimide Chemical Properties,Usage,Production

Description

DBCO-Maleimide is a sulfhydryl reactive reagent containing a maleimide group and a DBCO moiety. Maleimide group specifically and efficiently reacts with thiols to form thioether bonds. The low mass weight will add minimal spacer to modified molecules and will enable simple and efficient incorporation of DBCO moiety into cysteine-containing peptides or other thiol-containing biomolecules. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

Protein-peptide conjugates
Antibody-enzyme or antibody-drug conjugates
Protein or peptide-oligonucleotide conjugates
Surface modification

Uses

Dbco-Maleimide is used in preparation of radioactive metal indicator-chelating peptide derivative-conjugated antibodies for medical imaging.

DBCO-maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DBCO-maleimide Suppliers

China 67 Europe 1 India 1 Japan 1 United States 7 Global 77

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

9i LLC

Tel: +18039569191
Fax: +13026429191
Email: MWan@NiNeiLab.com
Country: United States
ProdList: 418
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52924
Advantage: 58

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

PurePEG，LLC

Tel: --
Fax: --
Email: info@purepeg.com
Country: United States
ProdList: 697
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

More

Less

View Lastest Price from DBCO-maleimide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-Maleimide 1395786-30-7
Price: US $0.00/mg
Min. Order: 25mg
Purity: >98.00%
Supply Ability: 250
Release date: 2024-03-20

1395786-30-7, DBCO-maleimideRelated Search:

Oleic-DBCO DBCO-C-PEG1 DBCO-C6-acid DBCO-(CH2)2-NH2-CO-(CH2)2COOH DBCO-NHS Ester DBCO-(CH2)2-NH2-CO-(CH2)3COOH DBCO-(CH2)3-Acid DBCO-PEG11-amine 3-Maleimidopropionic acid DBCO-PEG4-Acid DBCO-PEG3-amine DBCO-amine 2-(4-Ethyl-1-piperazinyl)-4-[4-(4-ethyl-1-piperazinyl)phenyl]-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine DBCO-PEG4-amine DBCO-PEG4-maleimide BDP FL DBCO DBCO-PEG4-TAMRA DBCO-PEG5-CH2CH2COOH

DBCO-maleimide

Dibenzocyclooctyne-maleimide

Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.)

1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-

DBCO-Maleimide,Dibenzocyclooctyne-maleimide

DBCO-maleimide (This product is unavailable in the U.S.)

DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5)

N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide

DBCO-MAL

N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide

1395786-30-7

ADC LINKER