Neuraminidase
- Product Name
- Neuraminidase
- CAS No.
- 9001-67-6
- Chemical Name
- Neuraminidase
- Synonyms
- SIALIDASE;EC 3.2.1.18;SIALIDASE L;IUB: 3.2.1.18;ALP Separator;NEURAMINIDASE;Neuraminidase B;Neuraminidase A;exo-α-sialidase;3) Neuraminidase
- CBNumber
- CB9348886
- Molecular Formula
- NULL
- Formula Weight
- 0
- MOL File
- Mol file
Neuraminidase Property
- Density
- 1.00 g/mL at 20 °C
- storage temp.
- 2-8°C
- form
- lyophilized powder
- color
- white
- Water Solubility
- Soluble in water or 10mM phosphate buffer, pH 6.0
- EPA Substance Registry System
- Neuraminidase (9001-67-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H290May be corrosive to metals
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P234Keep only in original container.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N7885
- Product name
- Neuraminidase from Vibrio cholerae
- Purity
- Type III, buffered aqueous solution, 0.2 μm filtered, 1-5?units/mg protein (Lowry, using NAN-lactose)
- Packaging
- 1unit
- Price
- $181
- Updated
- 2024/03/01
- Product number
- N8271
- Product name
- α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens
- Purity
- recombinant, expressed in E. coli, buffered aqueous solution
- Packaging
- 0.2unit
- Price
- $638
- Updated
- 2024/03/01
- Product number
- N7885
- Product name
- Neuraminidase from Vibrio cholerae
- Purity
- Type III, buffered aqueous solution, 0.2 μm filtered, 1-5?units/mg protein (Lowry, using NAN-lactose)
- Packaging
- 2units
- Price
- $332
- Updated
- 2024/03/01
- Product number
- N5631
- Product name
- Neuraminidase from Clostridium perfringens (C. welchii)
- Purity
- Type VIII, lyophilized powder, 10-20?units/mg protein (using 4MU-NANA), 3.5-8.0?units/mg protein (mucin)
- Packaging
- 1unit
- Price
- $69.2
- Updated
- 2024/03/01
- Product number
- N5631
- Product name
- Neuraminidase from Clostridium perfringens (C. welchii)
- Purity
- Type VIII, lyophilized powder, 10-20?units/mg protein (using 4MU-NANA), 3.5-8.0?units/mg protein (mucin)
- Packaging
- 5units
- Price
- $226
- Updated
- 2024/03/01
Neuraminidase Chemical Properties,Usage,Production
Uses
Neuraminidase is used as a hydrolytic enzyme that removes sialic acid from mucoproteins, used in a study to assess binding with human T lymphocytes in sheep pretreated with neuraminidase. It has also been used in a study to investigate the effect of bile salts on the action of hydrolysis by neuraminidase.
Uses
Neuraminidase is an important deglycosylation enzyme capable of cleaving all non-reducing unbranched N-acetylneuraminic and N-glycolylneuraminic acid residues by hydrolysis of α(2→6), α(2→3), α(2→8), and α(2→9) linkages (affinity in the order given). Branched sialic acids may also be cleaved with the use of high concentrations of enzyme and prolonged incubations. Desialylated glycoproteins may then be further characterized by treatment with various exoglycosidases resulting in partial or complete O-deglycosylation. SDS-PAGE and MALDI-TOF MS are typically utilized in purification, structural analysis, and sequencing process. These techniques also remove heterogeneity and charge from the glycoprotein.
Uses
Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. It has also been used in a study to investigate modification of leukemia L1210 tumor cells.
General Description
Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.
Biochem/physiol Actions
Vibrio cholerae neuraminidase has been shown to promote cholera toxin infection by binding the toxin and aiding in its uptake by cells.
Neuraminidase Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Neuraminidase manufacturers
- Product
- neuraminidase 9001-67-6
- Price
- US $42.00-38.80/KU
- Min. Order
- 10KU
- Purity
- ≥400U/mg
- Supply Ability
- 1000ku
- Release date
- 2020-11-04
- Product
- ACETYLNEURAMINYL HYDROLASE 9001-67-6
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 100kg
- Release date
- 2020-01-07