Ethyl 2-chloroacetoacetate
- Product Name
- Ethyl 2-chloroacetoacetate
- CAS No.
- 609-15-4
- Chemical Name
- Ethyl 2-chloroacetoacetate
- Synonyms
- Ethyl 2-chloro-3-oxobutanoate;2-chloroacetoacetate;2-CHLORACETYLETHYL ACETATE;2-Chloro-3-oxobutanoic acid, ethyl ester;Butanoic acid, 2-chloro-3-oxo-, ethyl ester;A 21960;2-CL-ACE;AKOS BBS-00004302;Ethyl 2-chloroacetoa;Oxiracetam Impurity 12
- CBNumber
- CB9396009
- Molecular Formula
- C6H9ClO3
- Formula Weight
- 164.59
- MOL File
- 609-15-4.mol
Ethyl 2-chloroacetoacetate Property
- Melting point:
- -80 °C
- Boiling point:
- 107 °C/14 mmHg (lit.)
- Density
- 1.19 g/mL at 25 °C (lit.)
- vapor pressure
- 49.4-100Pa at 20℃
- refractive index
- n20/D 1.441(lit.)
- Flash point:
- 122 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly)
- form
- Liquid
- pka
- 7.92±0.46(Predicted)
- color
- Clear yellow
- Water Solubility
- 17 g/L (20 ºC)
- BRN
- 774278
- LogP
- 1.2 at 20℃ and pH1-7
- Surface tension
- 69.4mN/m at 1g/L and 20℃
- CAS DataBase Reference
- 609-15-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Butanoic acid, 2-chloro-3-oxo-, ethyl ester(609-15-4)
- EPA Substance Registry System
- Ethyl 2-chloroacetoacetate (609-15-4)
Safety
- Hazard Codes
- C,Xn,F
- Risk Statements
- 10-22-34-52/53-36/37/38-36
- Safety Statements
- 16-26-36/37/39-45-61-37/39
- RIDADR
- UN 2920 8/PG 2
- WGK Germany
- 2
- F
- 19
- Hazard Note
- Corrosive
- TSCA
- Yes
- HazardClass
- 3.2
- PackingGroup
- III
- HS Code
- 29183000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C1218
- Product name
- Ethyl 2-Chloroacetoacetate
- Purity
- >95.0%(GC)
- Packaging
- 25g
- Price
- $19
- Updated
- 2024/03/01
- Product number
- C1218
- Product name
- Ethyl 2-Chloroacetoacetate
- Purity
- >95.0%(GC)
- Packaging
- 500g
- Price
- $137
- Updated
- 2024/03/01
- Product number
- A19810
- Product name
- Ethyl 2-chloroacetoacetate, 96%
- Packaging
- 100g
- Price
- $38.2
- Updated
- 2024/03/01
- Product number
- A19810
- Product name
- Ethyl 2-chloroacetoacetate, 96%
- Packaging
- 500g
- Price
- $145
- Updated
- 2024/03/01
- Product number
- E16902
- Product name
- Ethyl 2-chloroacetoacetate
- Purity
- 95%
- Packaging
- 500g
- Price
- $87
- Updated
- 2022/05/15
Ethyl 2-chloroacetoacetate Chemical Properties,Usage,Production
Chemical Properties
clear bright yellow liquid
Uses
Ethyl 2-chloroacetoacetate was used to study reductive dechlorination of β-keto ester ethyl 2-chloroacetoacetate by Saccharomyces cerevisiae.
Biochem/physiol Actions
Ethyl 2-chloroacetoacetate reacts with thiosemicarbazones to form heterocyclic substituted thiophene derivatives having non-steroidal anti-inflammatory activity.
Synthesis
Using ethyl acetoacetate and thionyl chloride as raw materials, the condensation reaction is carried out in the presence of a solvent. The dosage ratio of ethyl acetoacetate, thionyl chloride, and solvent is 1:1.37~2.75:2.31~4.62 by mass, the temperature of the condensation reaction is 75~95°C, and the reaction time is 5.5-9h. After stopping the reaction, evaporate most of the solvent and unreacted thionyl chloride under normal pressure, and then distill the remaining organic phase under reduced pressure to collect the 107-108°C/1.87kPa fraction to obtain Ethyl 2-chloroacetoacetate Products. The solvents used were n-heptane or, dichloroethane or toluene.
Ethyl 2-chloroacetoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl 2-chloroacetoacetate manufacturers
- Product
- Ethyl 2-chloroacetoacetate 609-15-4
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-05-26
- Product
- Ethyl 2-chloroacetoacetate 609-15-4
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2023-05-08
- Product
- Ethyl 2-chloroacetoacetate 609-15-4
- Price
- US $1.00/PCS
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2021-07-07