Pyridine compound
Pyridine compound is one of the most widely developed and used heterocyclic compound. As an important fine chemical raw material, its derivatives mainly include alkyl pyridine, halogenated pyridine, aminopyridine, bromo pyridine, picoline , iodine pyridine, chloropyridine, nitropyridine-hydroxypyridine, benzyl pyridine, ethyl pyridine, pyridine cyano, fluoro pyridine, dihydropyridine, etc., in which the pesticide accounts for about 50% of the total consumption of pyridine products, feed additive about 30% and medicine and other areas 20%.
Pyridine is a colorless or slightly yellow liquid that has weak alkaline and special odor. It is an important chemical raw material and solvent, which naturally presents in coal tar, shale oil, gas and petroleum and is miscible with most of the water, alcohols, ethers, petroleum ether, oils, benzene, chloroform and other organic solvents.
The important derivatives of pyridine mainly include nicotinic acid, nicotinamide, isonicotinic hydrazide, nicotine, strychnine, and vitamin B6.
Pyridine has a close hexagonal structure that is similar to benzene. Because of the electron-withdrawing effect of the nitrogen atom in the ring, the electron density of 2,4,6 positions is less than that of 3,5 positions. In an acidic medium, electrophilic substitution reactions occur in the 3,5 positions and nucleophilic reactions, such as amination, alkylation, arylation, acylation, occur in the 2,4,6 positions. Pyridine is a weak tertiary amine, which can form different water-soluble salts with various acids (such as picric acid, perchloric acid or the like) in an ethanol solution. Due to the alkaline of pyridine, it can generate hydrochloride (C5H5N•HCl)with hydrochloric acid. In the effect of nickel catalyst at 200 ℃ and 15-30MPa, it can generate piperidine via hydrogenation or electrolysis reduction. The reduction of pyridine is easier than benzene, while the oxidation is more difficult than benzene. But we can oxidize pyridine by the catalysis of hydrogen peroxide or peroxy acids. N-pyridine oxide is an important pyridine derivative, which is easier for the happen of aryl group electrophilic substitution reaction because the oxidation of nitrogen atoms make the formation of positively charged pyridinium cation impossible. Electrophilic substitutions, such as pyridine nitration, sulfonation, halogenation, are relatively difficult, but the previous actions are slightly easier than halogenation. We can obtain 3,5-dichloro-pyridine or 3,4,5-trichloro pyridine via pyridine nitration and sulfonation at more than 200℃. Pyridine can form many crystalline complex compounds with various metal ions.
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- Structure:
- Chemical Name:
- ETHYL 4-PYRIDYLACETATE
- CAS:
- 54401-85-3
- MF:
- C9H11NO2
- Structure:
- Chemical Name:
- 4-Chlorothieno[3,2-c]pyridine
- CAS:
- 27685-94-5
- MF:
- C7H4ClNS
- Structure:
- Chemical Name:
- 2,6-Dichloro-3-(trifluoromethyl)pyridine
- CAS:
- 55304-75-1
- MF:
- C6H2Cl2F3N
- Structure:
- Chemical Name:
- 2,6-BIS(TRIFLUOROMETHYL)PYRIDINE
- CAS:
- 455-00-5
- MF:
- C7H3F6N
- Structure:
- Chemical Name:
- 7-METHYL-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
- CAS:
- 70705-33-8
- MF:
- C11H12N2O2
- Structure:
- Chemical Name:
- 2,3,4,6-TETRAFLUOROPYRIDINE
- CAS:
- 3512-13-8
- MF:
- C5HF4N
- Structure:
- Chemical Name:
- 2-AMINOPYRIDINE-5-SULFONIC ACID
- CAS:
- 16250-08-1
- MF:
- C5H6N2O3S
- Structure:
- Chemical Name:
- 2-FLUORO-6-PICOLINE-5-BORONIC ACID
- CAS:
- 904326-91-6
- MF:
- C6H7BFNO2
- Structure:
- Chemical Name:
- 3,5-DICHLORO-2,6-DIFLUOROPYRIDINE-4-CARBOXALDEHYDE
- CAS:
- 17723-32-9
- MF:
- C6HCl2F2NO
- Structure:
- Chemical Name:
- 2-METHYLNICOTINALDEHYDE
- CAS:
- 60032-57-7
- MF:
- C7H7NO
- Structure:
- Chemical Name:
- 2-METHYL-5-IODOPYRIDINE
- CAS:
- 695-17-0
- MF:
- C6H6IN
- Structure:
- Chemical Name:
- 3,4,5,6-Tetrachloropyridine-2-carbonitrile
- CAS:
- 17824-83-8
- MF:
- C6Cl4N2
- Structure:
- Chemical Name:
- 2,4,6-TRIBROMO-3-PYRIDINOL
- CAS:
- 6602-34-2
- MF:
- C5H2Br3NO
- Structure:
- Chemical Name:
- 2-Chloromethyl-3-methyl-4-(3-methoxypropoxy)pyridine hydrochloride
- CAS:
- 153259-31-5
- MF:
- C11H17Cl2NO2
- Structure:
- Chemical Name:
- 2-Amino-4-chloro-6-picoline
- CAS:
- 36340-61-1
- MF:
- C6H7ClN2
- Structure:
- Chemical Name:
- CHEMPACIFIC 38154
- CAS:
- 84487-04-7
- MF:
- C5H4BrN3O2
- Structure:
- Chemical Name:
- (5-CHLORO-2-FLUOROPYRIDIN-4-YL)BORONIC ACID
- CAS:
- 1034659-38-5
- MF:
- C5H4BClFNO2
- Structure:
- Chemical Name:
- 2-Bromo-4-methoxypyridine
- CAS:
- 89488-29-9
- MF:
- C6H6BrNO
- Structure:
- Chemical Name:
- 2-Amino-6-chloro-4-picoline
- CAS:
- 51564-92-2
- MF:
- C6H7ClN2
- Structure:
- Chemical Name:
- 3-Chloro-4-fluoropyridine
- CAS:
- 883107-69-5
- MF:
- C5H3ClFN
- Structure:
- Chemical Name:
- 5-Chloropyridine-2-thiol
- CAS:
- 40771-41-3
- MF:
- C5H4ClNS
- Structure:
- Chemical Name:
- 4-Cyano-3-methylpyridine
- CAS:
- 7584-05-6
- MF:
- C7H6N2
- Structure:
- Chemical Name:
- 2-TRIFLUOROMETHYL-3-AMINOPYRIDINE
- CAS:
- 106877-32-1
- MF:
- C6H5F3N2
- Structure:
- Chemical Name:
- 6-BENZYL-5,7-DIOXO-OCTAHYDROPYRROLO[3,4-B] PYRIDINE
- CAS:
- 128740-13-6
- MF:
- C14H16N2O2
- Structure:
- Chemical Name:
- 4-Chloro-5-fluoro-2-methylpyridine
- CAS:
- 169750-95-2
- MF:
- C6H5ClFN
- Structure:
- Chemical Name:
- 3-OXO-3-(3-PYRIDINYL)PROPANENITRILE
- CAS:
- 30510-18-0
- MF:
- C8H6N2O
- Structure:
- Chemical Name:
- 4-Amino-3,5-difluoropyridine
- CAS:
- 159783-22-9
- MF:
- C5H4F2N2
- Structure:
- Chemical Name:
- 2,5-DIBROMO-3-AMINOPYRIDINE
- CAS:
- 90902-84-4
- MF:
- C5H4Br2N2
- Structure:
- Chemical Name:
- 2-Pyridyl tribromomethyl sulfone
- CAS:
- 59626-33-4
- MF:
- C6H4Br3NO2S
- Structure:
- Chemical Name:
- N-BUTYL-3-METHYLPYRIDINIUM BROMIDE
- CAS:
- 26576-85-2
- MF:
- C10H16BrN
- Structure:
- Chemical Name:
- 2-Pyridinecarboxaldehyde,6-(fluoromethyl)-(9CI)
- CAS:
- 208111-28-8
- MF:
- C7H6FNO
- Structure:
- Chemical Name:
- 5H-Cyclopenta[b]pyridin-5-amine,6,7-dihydro-(9CI)
- CAS:
- 535935-84-3
- MF:
- C8H10N2
- Structure:
- Chemical Name:
- (2-Chloropyridin-3-yl)methanamine
- CAS:
- 205744-14-5
- MF:
- C6H7ClN2
- Structure:
- Chemical Name:
- 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE
- CAS:
- 72537-17-8
- MF:
- C6H2ClF4N
- Structure:
- Chemical Name:
- 2,4-Dichloro-3-iodopyridine
- CAS:
- 343781-36-2
- MF:
- C5H2Cl2IN
- Structure:
- Chemical Name:
- 1-(5-Nitro-2-pyridinyl)piperidine-4-carboxylic acid
- CAS:
- 868077-44-5
- MF:
- C11H13N3O4
- Structure:
- Chemical Name:
- DIMETHYL 5-BROMOPYRIDINE-2,3-DICARBOXYLATE
- CAS:
- 98555-51-2
- MF:
- C7H4BrNO4
- Structure:
- Chemical Name:
- 5-BROMO-2-FLUORONICOTINIC ACID
- CAS:
- 29241-66-5
- MF:
- C6H3BrFNO2
- Structure:
- Chemical Name:
- 4-Bromo-2,6-diethyl-pyridine
- CAS:
- 877133-54-5
- MF:
- C9H12BrN
- Structure:
- Chemical Name:
- benzyl 3,4-dihydro-2-methyl-4-oxopyridine-1(2H)-carboxylate
- CAS:
- 190906-91-3
- MF:
- C14H15NO3
- Structure:
- Chemical Name:
- Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir
- CAS:
- 198904-86-8
- MF:
- C32H42N4O5
- Structure:
- Chemical Name:
- 2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE
- CAS:
- 408502-23-8
- MF:
- C12H18BNO3
- Structure:
- Chemical Name:
- 6-METHYL-2,3-PYRIDINEDICARBOXYLIC ACID
- CAS:
- 53636-70-7
- MF:
- C8H7NO4
- Structure:
- Chemical Name:
- 5-tert-butyl 2-ethyl 6,7-dihydrothiazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate
- CAS:
- 1053656-51-1
- MF:
- C14H20N2O4S
- Structure:
- Chemical Name:
- 2-METHYLPYRIDINE-4-SULFONIC ACID
- CAS:
- 408533-46-0
- MF:
- C6H7NO3S
- Structure:
- Chemical Name:
- 3-BROMOISONICOTINIC ACID METHYL ESTER
- CAS:
- 59786-31-1
- MF:
- C7H6BrNO2
- Structure:
- Chemical Name:
- 4-(5-NITROPYRIDIN-2-YL)BENZOIC ACID
- CAS:
- 223127-49-9
- MF:
- C12H8N2O4
- Structure:
- Chemical Name:
- 2,6-DIMETHYLPYRIDINIUM P-TOLUENESULFONATE
- CAS:
- 93471-41-1
- MF:
- C14H17NO3S
- Structure:
- Chemical Name:
- 2,6-Dimethoxypyridine-3-carboxylic acid
- CAS:
- 16727-43-8
- MF:
- C8H9NO4
- Structure:
- Chemical Name:
- (2-Methyl-6-trifluoromethylpyridin-3-yl)amine
- CAS:
- 383907-17-3
- MF:
- C7H7F3N2
- Structure:
- Chemical Name:
- 4-CYANO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)PYRIDINE
- CAS:
- 878194-91-3
- MF:
- C12H15BN2O2
- Structure:
- Chemical Name:
- 2-FLUORO-3,4-DIIODOPYRIDINE
- CAS:
- 153034-83-4
- MF:
- C5H2FI2N
- Structure:
- Chemical Name:
- N719
- CAS:
- 207347-46-4
- MF:
- 2C16H36N.2C12H7N2O4.C2N2RuS2
- Structure:
- Chemical Name:
- 2-AMINO-3-CHLORO-5-BROMOPYRIDINE
- CAS:
- 38185-55-6
- MF:
- C5H4BrClN2
- Structure:
- Chemical Name:
- Pyridine hydrofluoride
- CAS:
- 62778-11-4
- MF:
- C5H6FN
- Structure:
- Chemical Name:
- 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE
- CAS:
- 496-13-9
- MF:
- C7H8N2
- Structure:
- Chemical Name:
- 5-AMINO-2-METHOXY-ISONICOTINIC ACID
- CAS:
- 183741-91-5
- MF:
- C7H8N2O3
- Structure:
- Chemical Name:
- 1-(3-METHYLPYRIDIN-2-YL)PIPERAZINE
- CAS:
- 111960-11-3
- MF:
- C10H15N3
- Structure:
- Chemical Name:
- 2,6-DIMETHYL-NICOTINIC ACID
- CAS:
- 5860-71-9
- MF:
- C8H9NO2
- Structure:
- Chemical Name:
- N-BOC-4-(4-CARBOXYPHENYL) PIPERIDINE
- CAS:
- 149353-75-3
- MF:
- C17H23NO4
- Structure:
- Chemical Name:
- 5-NITRO-2-HYDROXY-4-METHOXYPYRIDINE
- CAS:
- 607373-82-0
- MF:
- C6H6N2O4
- Structure:
- Chemical Name:
- 2-(BROMOACETYL)PYRIDINE HYDROBROMIDE
- CAS:
- 17570-98-8
- MF:
- C7H7Br2NO
- Structure:
- Chemical Name:
- 2-METHYL-5-NITROPYRIDIN-3-AMINE
- CAS:
- 51984-61-3
- MF:
- C6H7N3O2
- Structure:
- Chemical Name:
- 3-Methylpyridine-4-sulfonic acid
- CAS:
- 14045-23-9
- MF:
- C6H7NO3S
- Structure:
- Chemical Name:
- N-(3-IODO-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE
- CAS:
- 113975-33-0
- MF:
- C10H13IN2O
- Structure:
- Chemical Name:
- 2-N-BUTOXYPYRIDINE
- CAS:
- 27361-16-6
- MF:
- C9H13NO
- Structure:
- Chemical Name:
- 2-Bromo-3-(bromomethyl)pyridine
- CAS:
- 94446-97-6
- MF:
- C6H5Br2N
- Structure:
- Chemical Name:
- (6-AMINOPYRIDIN-3-YL)BORONIC ACID
- CAS:
- 851524-96-4
- MF:
- C5H7BN2O2
- Structure:
- Chemical Name:
- 5-NITROPYRIDINE-2,3-DIAMINE
- CAS:
- 3537-14-2
- MF:
- C5H6N4O2
- Structure:
- Chemical Name:
- 6-AMINO-PYRIDIN-3-OL HYDROCHLORIDE
- CAS:
- 856965-37-2
- MF:
- C5H7ClN2O
- Structure:
- Chemical Name:
- 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE
- CAS:
- 62459-02-3
- MF:
- C14H15N3O2
- Structure:
- Chemical Name:
- 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride
- CAS:
- 97657-92-6
- MF:
- C21H25N3.2ClH
- Structure:
- Chemical Name:
- 2-Amino-5-bromo-3-(trifluoromethyl)pyridine
- CAS:
- 79456-34-1
- MF:
- C6H4BrF3N2
- Structure:
- Chemical Name:
- 6-AMINO-3,5-DINITROPYRIDINE
- CAS:
- 3073-30-1
- MF:
- C5H4N4O4
- Structure:
- Chemical Name:
- DIMETHYL-PYRIDIN-3-YL-AMINE
- CAS:
- 18437-57-5
- MF:
- C7H10N2
- Structure:
- Chemical Name:
- 4,4'-DIPYRIDYL DISULFIDE
- CAS:
- 2645-22-9
- MF:
- C10H8N2S2
- Structure:
- Chemical Name:
- 3-AMINO-2-PYRIDINE SULFONIC ACID
- CAS:
- 54247-51-7
- MF:
- C5H6N2O3S
- Structure:
- Chemical Name:
- 2-PYRIDYLHYDROXYMETHANESULFONIC ACID
- CAS:
- 3343-41-7
- MF:
- C6H7NO4S
- Structure:
- Chemical Name:
- 2-CYCLOPROPYLMETHOXY-3-IODO-PYRIDINE
- CAS:
- 766557-62-4
- MF:
- C9H10INO
- Structure:
- Chemical Name:
- 2-(3-HYDROXYCARBONYL-6-PYRIDYL)MALONDIALDEHYDE
- CAS:
- 180615-36-5
- MF:
- C9H7NO4
- Structure:
- Chemical Name:
- 5,6-Dimethylpyridin-2-amine
- CAS:
- 57963-08-3
- MF:
- C7H10N2
- Structure:
- Chemical Name:
- 3,5-Diethyl-1,2-dihydro-1-phenyl-2-propylpyridine
- CAS:
- 34562-31-7
- MF:
- C18H25N
- Structure:
- Chemical Name:
- PYRIDINE-2-THIOAMIDE
- CAS:
- 5346-38-3
- MF:
- C6H6N2S
- Structure:
- Chemical Name:
- 2-CYANO-4-METHYL-5-NITROPYRIDINE
- CAS:
- 267875-30-9
- MF:
- C7H5N3O2
- Structure:
- Chemical Name:
- N-FLUORO-4-METHYLPYRIDINIUM-2-SULFONATE
- CAS:
- 147540-88-3
- MF:
- C6H6FNO3S
- Structure:
- Chemical Name:
- 2-FLUORO-3-HYDROXY-6-PICOLINE
- CAS:
- 209328-87-0
- MF:
- C6H6FNO
- Structure:
- Chemical Name:
- 2-HYDROXYMETHYL-3-METHYLPYRIDINE
- CAS:
- 63071-09-0
- MF:
- C7H9NO
- Structure:
- Chemical Name:
- 2-BROMOPYRIDINE N-OXIDE
- CAS:
- 14305-17-0
- MF:
- C5H4BrNO
- Structure:
- Chemical Name:
- 4-(4,4-DIMETHYL-PIPERIDIN-1-YL)-BENZOIC ACID
- CAS:
- 406233-26-9
- MF:
- C14H19NO2
- Structure:
- Chemical Name:
- 2-BENZYLOXY-5-BROMOPYRIDINE
- CAS:
- 83664-33-9
- MF:
- C12H10BrNO
- Structure:
- Chemical Name:
- 5-BROMO-2-HYDROXY-4-PYRIDINECARBOXYLIC ACID
- CAS:
- 913836-16-5
- MF:
- C6H4BrNO3
- Structure:
- Chemical Name:
- methyl 6-methylpyridine-2-carboxylate
- CAS:
- 13602-11-4
- MF:
- C8H9NO2
- Structure:
- Chemical Name:
- 5-bromo-6-methyl-3-nitropyridin-2-amine
- CAS:
- 68957-50-6
- MF:
- C6H6BrN3O2
- Structure:
- Chemical Name:
- 2-Bromo-3-chloro-5-hydroxypyridine
- CAS:
- 130284-56-9
- MF:
- C5H3BrClNO
- Structure:
- Chemical Name:
- 2-Iodo-5-trifluoromethylpyridine
- CAS:
- 100366-75-4
- MF:
- C6H3F3IN
- Structure:
- Chemical Name:
- 3,4,5-Trichloropyridine-2-carboxylic acid
- CAS:
- 5439-04-3
- MF:
- C6H2Cl3NO2
- Structure:
- Chemical Name:
- 6-Aminopyridine-2-carboxylic acid ethyl ester
- CAS:
- 69142-64-9
- MF:
- C8H10N2O2
- Structure:
- Chemical Name:
- Minodronic acid
- CAS:
- 180064-38-4
- MF:
- C9H12N2O7P2
- Structure:
- Chemical Name:
- 2-Hyrdoxy-4-Methyl-5-Nitropyridine
- CAS:
- 21091-41-7
- MF:
- C6H6N2O3
- Structure:
- Chemical Name:
- 2-Hydroxy-3-Nitro-6-Chloropyridine
- CAS:
- 92138-35-7
- MF:
- C5H3ClN2O3