Antineoplastic agents
Hormonal antineoplastic drugs
Antimetabolites, Antineoplastic
Antibiotics anticancer drugs
Antitumor Adjuvant Drugs
Other antineoplastic Drugs
Natural sources of antineoplastic
Alkylating antineoplastic
Tinib Antineoplastic drugs
Idiopathic pulmonary fibrosis(IPF)
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Antineoplastic is a class of medicine to restrain or kill tumor cells in the body. It plays an important role in comprehensive cancer treatment, particularly for disseminated tumor and leukemia that cannot be treated with surgery. Most current antineoplastics work by inhibiting DNA or RNA synthesis, or even damaging the structure of DNA. Antineoplastics can be divided into CCNSA (Cell cycle nonspecific drug) and CCSA (Cell Cycle Specific agents) according to their different effect on tumor cells in different stages of generation cycles. Both of them have a killing effect on bone marrow hematopoietic stem cells and other cells with a short growth cycle, as well as an inhibiting effect on the body's immune response.
Antineoplastic has a wide variety of drugs, which can be divided into following categories:
alkylating agents, such as cyclophosphamide, Glyciphosphoramide, thiotepa, etc.;
antimetabolites, such as methotrexate, mercaptopurine, fluorouracil, hydroxyurea, etc.;
antibiotics, such as dactinomycin, mitomycin C, bleomycin, etc.;
hormones, such as prednisone, testosterone propionate, diethylstilbestrol, etc.;
some botanical drugs, such as Vinblastine, camptothecin, colchicine, etc.;
and other classes, such as procarbazine, propylene imine, Yishuangmalin, etc.
With their enormous diversity and different mechanisms, antineoplastics must be carefully selected for clinical application.
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- Structure:
- Chemical Name:
- PLX4032
- CAS:
- 918504-65-1
- MF:
- C23H18ClF2N3O3S
- Structure:
- Chemical Name:
- 10-Hydroxycamptothecin
- CAS:
- 64439-81-2
- MF:
- C20H16N2O5
- Structure:
- Chemical Name:
- Raloxifene
- CAS:
- 84449-90-1
- MF:
- C28H27NO4S
- Structure:
- Chemical Name:
- Topotecan hydrochloride
- CAS:
- 119413-54-6
- MF:
- C23H24ClN3O5
- Structure:
- Chemical Name:
- Pemetrexed Disodium
- CAS:
- 150399-23-8
- MF:
- C20H22N5NaO6
- Structure:
- Chemical Name:
- 10-Hydroxycamptothecin
- CAS:
- 19685-09-7
- MF:
- C20H16N2O5
- Structure:
- Chemical Name:
- Pirfenidone
- CAS:
- 53179-13-8
- MF:
- C12H11NO
- Structure:
- Chemical Name:
- 7-Ethyl-10-hydroxycamptothecin
- CAS:
- 86639-52-3
- MF:
- C22H20N2O5
- Structure:
- Chemical Name:
- Exemestane
- CAS:
- 107868-30-4
- MF:
- C20H24O2
- Structure:
- Chemical Name:
- Imatinib mesylate
- CAS:
- 220127-57-1
- MF:
- C30H35N7O4S
- Structure:
- Chemical Name:
- Gefitinib
- CAS:
- 184475-35-2
- MF:
- C22H24ClFN4O3
- Structure:
- Chemical Name:
- Bortezomib
- CAS:
- 179324-69-7
- MF:
- C19H25BN4O4
- Structure:
- Chemical Name:
- Rubitecan
- CAS:
- 91421-42-0
- MF:
- C20H15N3O6
- Structure:
- Chemical Name:
- Erlotinib
- CAS:
- 183321-74-6
- MF:
- C22H23N3O4
- Structure:
- Chemical Name:
- Letrozole
- CAS:
- 112809-51-5
- MF:
- C17H11N5
- Structure:
- Chemical Name:
- Cisplatin
- CAS:
- 15663-27-1
- MF:
- Cl2H6N2Pt
- Structure:
- Chemical Name:
- Valrubicin
- CAS:
- 56124-62-0
- MF:
- C34H36F3NO13
- Structure:
- Chemical Name:
- Vinorelbine tartrate
- CAS:
- 125317-39-7
- MF:
- C53H66N4O20
- Structure:
- Chemical Name:
- Vandetanib
- CAS:
- 443913-73-3
- MF:
- C22H24BrFN4O2
- Structure:
- Chemical Name:
- Docetaxel
- CAS:
- 114977-28-5
- MF:
- C43H53NO14
- Structure:
- Chemical Name:
- 17-AAG
- CAS:
- 75747-14-7
- MF:
- C31H43N3O8
- Structure:
- Chemical Name:
- Oxaliplatin
- CAS:
- 61825-94-3
- MF:
- C8H12N2O4Pt
- Structure:
- Chemical Name:
- Sunitinib Malate
- CAS:
- 341031-54-7
- MF:
- C26H33FN4O7
- Structure:
- Chemical Name:
- Clofarabine
- CAS:
- 123318-82-1
- MF:
- C10H11ClFN5O3
- Structure:
- Chemical Name:
- Erlotinib hydrochloride
- CAS:
- 183319-69-9
- MF:
- C22H24ClN3O4
- Structure:
- Chemical Name:
- (+)-Camptothecin
- CAS:
- 7689-03-4
- MF:
- C20H16N2O4
- Structure:
- Chemical Name:
- Combretastatin A4 phosphate disodium salt
- CAS:
- 168555-66-6
- MF:
- C18H19O8P.2Na
- Structure:
- Chemical Name:
- Temozolomide
- CAS:
- 85622-93-1
- MF:
- C6H6N6O2
- Structure:
- Chemical Name:
- Methotrexate
- CAS:
- 59-05-2
- MF:
- C20H22N8O5
- Structure:
- Chemical Name:
- Neratinib
- CAS:
- 698387-09-6
- MF:
- C30H29ClN6O3
- Structure:
- Chemical Name:
- Anastrozole
- CAS:
- 120511-73-1
- MF:
- C17H19N5
- Structure:
- Chemical Name:
- Floxuridine
- CAS:
- 50-91-9
- MF:
- C9H11FN2O5
- Structure:
- Chemical Name:
- Paclitaxel
- CAS:
- 33069-62-4
- MF:
- C47H51NO14
- Structure:
- Chemical Name:
- Lenalidomide
- CAS:
- 191732-72-6
- MF:
- C13H13N3O3
- Structure:
- Chemical Name:
- Cediranib
- CAS:
- 288383-20-0
- MF:
- C25H27FN4O3
- Structure:
- Chemical Name:
- Gemcitabine
- CAS:
- 95058-81-4
- MF:
- C9H11F2N3O4
- Structure:
- Chemical Name:
- Doxifluridine
- CAS:
- 3094-09-5
- MF:
- C9H11FN2O5
- Structure:
- Chemical Name:
- Dasatinib
- CAS:
- 302962-49-8
- MF:
- C22H26ClN7O2S
- Structure:
- Chemical Name:
- Nilotinib
- CAS:
- 641571-10-0
- MF:
- C28H22F3N7O
- Structure:
- Chemical Name:
- Cytarabine
- CAS:
- 147-94-4
- MF:
- C9H13N3O5
- Structure:
- Chemical Name:
- 6-Thioguanine
- CAS:
- 154-42-7
- MF:
- C5H5N5S
- Structure:
- Chemical Name:
- Colchicine
- CAS:
- 64-86-8
- MF:
- C22H25NO6
- Structure:
- Chemical Name:
- Bosutinib
- CAS:
- 380843-75-4
- MF:
- C26H29Cl2N5O3
- Structure:
- Chemical Name:
- Carboplatin
- CAS:
- 41575-94-4
- MF:
- C6H12N2O4Pt
- Structure:
- Chemical Name:
- Daunorubicin hydrochloride
- CAS:
- 23541-50-6
- MF:
- C27H29NO10.ClH
- Structure:
- Chemical Name:
- Mizolastine
- CAS:
- 108612-45-9
- MF:
- C24H25FN6O
- Structure:
- Chemical Name:
- Gemcitabine hydrochloride
- CAS:
- 122111-03-9
- MF:
- C9H11F2N3O4.ClH
- Structure:
- Chemical Name:
- Resveratrol
- CAS:
- 501-36-0
- MF:
- C14H12O3
- Structure:
- Chemical Name:
- Fludarabine phosphate
- CAS:
- 75607-67-9
- MF:
- C10H13FN5O7P
- Structure:
- Chemical Name:
- Imatinib
- CAS:
- 152459-95-5
- MF:
- C29H31N7O
- Structure:
- Chemical Name:
- Axitinib
- CAS:
- 319460-85-0
- MF:
- C22H18N4OS
- Structure:
- Chemical Name:
- Fludarabine
- CAS:
- 21679-14-1
- MF:
- C10H12FN5O4
- Structure:
- Chemical Name:
- Etoposide
- CAS:
- 33419-42-0
- MF:
- C29H32O13
- Structure:
- Chemical Name:
- Lapatinib
- CAS:
- 231277-92-2
- MF:
- C29H26ClFN4O4S
- Structure:
- Chemical Name:
- Nelarabine
- CAS:
- 121032-29-9
- MF:
- C11H15N5O5
- Structure:
- Chemical Name:
- Doxorubicin hydrochloride
- CAS:
- 25316-40-9
- MF:
- C27H29NO11.ClH
- Structure:
- Chemical Name:
- Canertinib
- CAS:
- 267243-28-7
- MF:
- C24H25ClFN5O3
- Structure:
- Chemical Name:
- Mitotan
- CAS:
- 53-19-0
- MF:
- C14H10Cl4
- Structure:
- Chemical Name:
- Fulvestrant
- CAS:
- 129453-61-8
- MF:
- C32H47F5O3S
- Structure:
- Chemical Name:
- Cantharidin
- CAS:
- 56-25-7
- MF:
- C10H12O4
- Structure:
- Chemical Name:
- Bendamustine hydrochloride
- CAS:
- 3543-75-7
- MF:
- C16H22Cl3N3O2
- Structure:
- Chemical Name:
- Canertinib dihydrochloride
- CAS:
- 289499-45-2
- MF:
- C24H27Cl3FN5O3
- Structure:
- Chemical Name:
- Irinotecan
- CAS:
- 97682-44-5
- MF:
- C33H38N4O6
- Structure:
- Chemical Name:
- Podophyllotoxin
- CAS:
- 518-28-5
- MF:
- C22H22O8
- Structure:
- Chemical Name:
- Topotecan
- CAS:
- 123948-87-8
- MF:
- C23H23N3O5
- Structure:
- Chemical Name:
- Busulfan
- CAS:
- 55-98-1
- MF:
- C6H14O6S2
- Structure:
- Chemical Name:
- Homoharringtonine
- CAS:
- 26833-87-4
- MF:
- C29H39NO9
- Structure:
- Chemical Name:
- Droloxifene
- CAS:
- 82413-20-5
- MF:
- C26H29NO2
- Structure:
- Chemical Name:
- Fruquintinib|HMPL-013
- CAS:
- 1194506-26-7
- MF:
- C21H19N3O5
- Structure:
- Chemical Name:
- Tegafur
- CAS:
- 17902-23-7
- MF:
- C8H9FN2O3
- Structure:
- Chemical Name:
- Flutamide
- CAS:
- 13311-84-7
- MF:
- C11H11F3N2O3
- Structure:
- Chemical Name:
- Epothilone D
- CAS:
- 189453-10-9
- MF:
- C27H41NO5S
- Structure:
- Chemical Name:
- (1S,3S,7S,10R,11S,12S,16R)-3-[(1E)-2-[2-(Aminomethyl)-4-thiazolyl]-1-methylethenyl]-7,11-dihydroxy-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
- CAS:
- 280578-49-6
- MF:
- C27H42N2O6S
- Structure:
- Chemical Name:
- LEE011
- CAS:
- 1256963-02-6
- MF:
- C22H29ClN8
- Chemical Name:
- Nivolumab
- CAS:
- 946414-94-4
- Structure:
- Chemical Name:
- Dasatinib monohydrate
- CAS:
- 863127-77-9
- MF:
- C22H28ClN7O3S
- Structure:
- Chemical Name:
- 2-AMINO-5-BROMO-4-HYDROXY-6-PHENYLPYRIMIDINE
- CAS:
- 56741-95-8
- MF:
- C10H8BrN3O
- Structure:
- Chemical Name:
- Regorafenib monohydrate
- CAS:
- 1019206-88-2
- MF:
- C21H17ClF4N4O4
- Structure:
- Chemical Name:
- 2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride
- CAS:
- 10212-25-6
- MF:
- C9H12ClN3O4
- Chemical Name:
- Enfortumab Vedotin
- CAS:
- 1346452-25-2
- Structure:
- Chemical Name:
- IXABEPILONE
- CAS:
- 219989-84-1
- MF:
- C27H42N2O5S
- Structure:
- Chemical Name:
- Trastuzumab
- CAS:
- 180288-69-1
- MF:
- C10H14N6O5
- Structure:
- Chemical Name:
- 9-(β-D-Xylofuranosyl)adenine
- CAS:
- 524-69-6
- MF:
- C10H13N5O4
- Structure:
- Chemical Name:
- Saracatinib
- CAS:
- 379231-04-6
- MF:
- C27H32ClN5O5
- Chemical Name:
- Ustekinumab
- CAS:
- 815610-63-0
- Structure:
- Chemical Name:
- Adalimumab
- CAS:
- 331731-18-1
- MF:
- C6428H9912N1694O1987S46
- Structure:
- Chemical Name:
- Mechlorethamine hydrochloride
- CAS:
- 55-86-7
- MF:
- C5H12Cl3N
- Structure:
- Chemical Name:
- epothilone F
- CAS:
- 208518-52-9
- MF:
- C27H41NO7S
- Structure:
- Chemical Name:
- Nintedanib
- CAS:
- 656247-17-5
- MF:
- C31H33N5O4
- Structure:
- Chemical Name:
- Vinblastine sulfate
- CAS:
- 143-67-9
- MF:
- C46H60N4O13S
- Structure:
- Chemical Name:
- Dacarbazine
- CAS:
- 4342-03-4
- MF:
- C6H10N6O
- Structure:
- Chemical Name:
- Tamoxifen citrate
- CAS:
- 54965-24-1
- MF:
- C32H37NO8
- Chemical Name:
- Panitumumab
- CAS:
- 339177-26-3
- Structure:
- Chemical Name:
- Cetuximab
- CAS:
- 205923-56-4
- MF:
- C107H179N35O36S7
- Chemical Name:
- Denosumab
- CAS:
- 615258-40-7
- MF:
- C6404H9912N1724O2004S50
- Structure:
- Chemical Name:
- Bleomycin sulfate
- CAS:
- 9041-93-4
- MF:
- C110H168N34O46S7
- Structure:
- Chemical Name:
- Mitomycin C
- CAS:
- 50-07-7
- MF:
- C15H18N4O5
- Structure:
- Chemical Name:
- Maytansine
- CAS:
- 35846-53-8
- MF:
- C34H46ClN3O10
- Structure:
- Chemical Name:
- Sunitinib
- CAS:
- 557795-19-4
- MF:
- C22H27FN4O2
- Structure:
- Chemical Name:
- BEPOTASTINE BESILATE
- CAS:
- 190786-44-8
- MF:
- C27H31ClN2O6S