Antineoplastic agents
Hormonal antineoplastic drugs
Antimetabolites, Antineoplastic
Antibiotics anticancer drugs
Antitumor Adjuvant Drugs
Other antineoplastic Drugs
Natural sources of antineoplastic
Alkylating antineoplastic
Tinib Antineoplastic drugs
Idiopathic pulmonary fibrosis(IPF)
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Antineoplastic is a class of medicine to restrain or kill tumor cells in the body. It plays an important role in comprehensive cancer treatment, particularly for disseminated tumor and leukemia that cannot be treated with surgery. Most current antineoplastics work by inhibiting DNA or RNA synthesis, or even damaging the structure of DNA. Antineoplastics can be divided into CCNSA (Cell cycle nonspecific drug) and CCSA (Cell Cycle Specific agents) according to their different effect on tumor cells in different stages of generation cycles. Both of them have a killing effect on bone marrow hematopoietic stem cells and other cells with a short growth cycle, as well as an inhibiting effect on the body's immune response.
Antineoplastic has a wide variety of drugs, which can be divided into following categories:
alkylating agents, such as cyclophosphamide, Glyciphosphoramide, thiotepa, etc.;
antimetabolites, such as methotrexate, mercaptopurine, fluorouracil, hydroxyurea, etc.;
antibiotics, such as dactinomycin, mitomycin C, bleomycin, etc.;
hormones, such as prednisone, testosterone propionate, diethylstilbestrol, etc.;
some botanical drugs, such as Vinblastine, camptothecin, colchicine, etc.;
and other classes, such as procarbazine, propylene imine, Yishuangmalin, etc.
With their enormous diversity and different mechanisms, antineoplastics must be carefully selected for clinical application.
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- Structure:
- Chemical Name:
- estra-1,3,5(10)-triene-3,17beta-diol 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate)
- CAS:
- 4891-15-0
- MF:
- C23H32Cl2NO6P
- Chemical Name:
- Estramustine Na PH
- Structure:
- Chemical Name:
- Chlormethine
- CAS:
- 51-75-2
- MF:
- C5H11Cl2N
- Structure:
- Chemical Name:
- 2,6-DIHYDROXY-4-METHYL-5-[BIS(2-CHLOROETHYL)AMINO]PYRIMIDINE
- CAS:
- 520-09-2
- MF:
- C9H13Cl2N3O2
- Structure:
- Chemical Name:
- BLEOMYCIN A5 HYDROCHLORIDE
- CAS:
- 55658-47-4
- MF:
- C57H90ClN19O21S2
- Structure:
- Chemical Name:
- iMatinib related substance C
- CAS:
- 938082-57-6
- MF:
- C29H31N7O2
- Structure:
- Chemical Name:
- brotianide
- CAS:
- 23233-88-7
- MF:
- C15H10Br2ClNO2S
- Structure:
- Chemical Name:
- SodiuM DeMethylcantharidate
- CAS:
- 33054-59-0
- MF:
- C8H11NaO5
- Structure:
- Chemical Name:
- BendaMustine IMpurity C
- CAS:
- 1313020-25-5
- MF:
- C19H27Cl2N3O2
- Structure:
- Chemical Name:
- DAUNOMYCINOL
- CAS:
- 28008-55-1
- MF:
- C27H31NO10
- Structure:
- Chemical Name:
- CHROMOMYCIN A3
- CAS:
- 7059-24-7
- MF:
- C57H82O26
- Structure:
- Chemical Name:
- Meisoindigo
- CAS:
- 97207-47-1
- MF:
- C17H12N2O2
- Structure:
- Chemical Name:
- Ancitabine
- CAS:
- 31698-14-3
- MF:
- C9H11N3O4
- Chemical Name:
- Predmustine
- Structure:
- Chemical Name:
- Antienite
- CAS:
- 5029-05-0
- MF:
- C9H8N2S2
- Structure:
- Chemical Name:
- Teniloxazine
- CAS:
- 62473-79-4
- MF:
- C16H19NO2S
- Chemical Name:
- Bleomycin hydrochloride
- CAS:
- 67763-87-5
- MF:
- C50H71N16O21S2R.x(HCl)
- Structure:
- Chemical Name:
- 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt
- CAS:
- 131374-93-1
- MF:
- C9H18N2O3Pt+2
- Structure:
- Chemical Name:
- EMITEFUR
- CAS:
- 110690-43-2
- MF:
- C28H19FN4O8
- Structure:
- Chemical Name:
- Ditiomustine
- CAS:
- 82599-22-2
- MF:
- C10H18Cl2N6O4S2
- Structure:
- Chemical Name:
- Neptamustine
- CAS:
- 73105-03-0
- MF:
- C8H16ClN3O2
- Structure:
- Chemical Name:
- motexafin gadolinium
- CAS:
- 156436-89-4
- MF:
- C52H74GdN5O15
- Chemical Name:
- IMatinib Meta-Methyl-piperazine
- Structure:
- Chemical Name:
- Ecomustine
- CAS:
- 98383-18-7
- MF:
- C10H18ClN3O6
- Structure:
- Chemical Name:
- Semustine
- CAS:
- 13909-09-6
- MF:
- C10H18ClN3O2
- Structure:
- Chemical Name:
- Streptonigrin
- CAS:
- 3930-19-6
- MF:
- C25H22N4O8
- Structure:
- Chemical Name:
- ACLARUBICIN HYDROCHLORIDE
- CAS:
- 75443-99-1
- MF:
- C42H54ClNO15
- Structure:
- Chemical Name:
- ZENIPLATIN
- CAS:
- 111490-36-9
- MF:
- C11H20N2O6Pt
- Structure:
- Chemical Name:
- Bisantrene
- CAS:
- 78186-34-2
- MF:
- C22H22N8
- Structure:
- Chemical Name:
- Tauromustine
- CAS:
- 85977-49-7
- MF:
- C7H15ClN4O4S
- Structure:
- Chemical Name:
- IMatinib Para-diaMinoMethylbenzene
- CAS:
- 1026753-54-7
- MF:
- C29H31N7O
- Structure:
- Chemical Name:
- URACIL MUSTARD
- CAS:
- 66-75-1
- MF:
- C8H11Cl2N3O2
- Structure:
- Chemical Name:
- 1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL
- CAS:
- 488-41-5
- MF:
- C6H12Br2O4
- Structure:
- Chemical Name:
- Tallimustine
- CAS:
- 115308-98-0
- MF:
- C32H38Cl2N10O4
- Structure:
- Chemical Name:
- Aclarubicin
- CAS:
- 57576-44-0
- MF:
- C42H53NO15
- Chemical Name:
- BendaMustine IMpurity B
- Structure:
- Chemical Name:
- Ranimustine
- CAS:
- 58994-96-0
- MF:
- C10H18ClN3O7
- Structure:
- Chemical Name:
- carboquone
- CAS:
- 24279-91-2
- MF:
- C15H19N3O5
- Structure:
- Chemical Name:
- Bleomycin A5
- CAS:
- 11116-32-8
- MF:
- C57H89N19O21S2
- Structure:
- Chemical Name:
- Betahistine Hydrochloride
- CAS:
- 15430-48-5
- MF:
- C8H13ClN2
- Structure:
- Chemical Name:
- Bofumustine
- CAS:
- 55102-44-8
- MF:
- C18H21ClN4O9
- Structure:
- Chemical Name:
- 4-[[[2-(Diethylamino)ethyl]amino]carbonyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid tert-butyl ester
- CAS:
- 590424-04-7
- MF:
- C18H31N3O3
- Structure:
- Chemical Name:
- 4,5-Bis(2-methoxyethoxy)-2-nitrobenzonitrile
- CAS:
- 236750-65-5
- MF:
- C13H16N2O6
- Structure:
- Chemical Name:
- BendaMustine IMpurity A
- CAS:
- 109882-26-0
- MF:
- Br-
- Structure:
- Chemical Name:
- DESACETYLVINBLASTINEAMIDE
- CAS:
- 53643-48-4
- MF:
- C43H55N5O7
- Structure:
- Chemical Name:
- TEGAFUR
- CAS:
- 37076-68-9
- MF:
- C8H9FN2O3
- Structure:
- Chemical Name:
- 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-hydroxyethoxy)quinazoline
- CAS:
- 183321-84-8
- MF:
- C20H19N3O4
- Structure:
- Chemical Name:
- elmustine
- CAS:
- 60784-46-5
- MF:
- C5H10ClN3O3
- Structure:
- Chemical Name:
- Ambamustine
- CAS:
- 85754-59-2
- MF:
- C29H39Cl2FN4O4S
- Structure:
- Chemical Name:
- Spiromustine
- CAS:
- 56605-16-4
- MF:
- C14H23Cl2N3O2
- Structure:
- Chemical Name:
- Tenilapine
- CAS:
- 82650-83-7
- Structure:
- Chemical Name:
- iMatinib related substance B
- CAS:
- 571186-93-1
- MF:
- C29H31N7O3
- Structure:
- Chemical Name:
- 2,6-PIPERAZINEDIONE, 4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-
- CAS:
- 21416-87-5
- MF:
- C11H16N4O4
- Structure:
- Chemical Name:
- FLUOROURACIL;FLURACIL
- MF:
- C8H5FN4O4
- Structure:
- Chemical Name:
- Enpromate
- CAS:
- 10087-89-5
- MF:
- C22H23NO2
- Chemical Name:
- GLYFOSFIN
- Structure:
- Chemical Name:
- NITROCAPHANE
- MF:
- C14H19Cl2N3O4
- Chemical Name:
- Methyl cantharidimide
- Structure:
- Chemical Name:
- tenylidone
- CAS:
- 893-01-6
- MF:
- C16H14OS2
- Chemical Name:
- Sorafenib Tosylate
- MF:
- C4H7NO4
- Chemical Name:
- Methoxymerphalan
- Structure:
- Chemical Name:
- Diazomycin B
- CAS:
- 7644-67-9
- MF:
- C17H23N7O8
- Structure:
- Chemical Name:
- (1alpha,2beta,4beta)-1-methyl-2,4-bis(methylvinyl)-1-vinylcyclohexane
- CAS:
- 33880-83-0
- MF:
- C15H24
- Chemical Name:
- Dianhydrodulcitol
- Chemical Name:
- Solaziquone
- Structure:
- Chemical Name:
- PEPLOMYCIN
- CAS:
- 68247-85-8
- MF:
- C61H88N18O21S2
- Chemical Name:
- Hydroxyl camptothecine
- Structure:
- Chemical Name:
- epipropidine
- CAS:
- 5696-17-3
- MF:
- C16H28N2O2
- Chemical Name:
- OCAPHANE
- Chemical Name:
- Mechlorethaminoxide
- Structure:
- Chemical Name:
- IRISQUINONE
- CAS:
- 56495-82-0
- MF:
- C24H38O3
- Chemical Name:
- SulfomercaprineSodium
- Structure:
- Chemical Name:
- mannomustine
- CAS:
- 576-68-1
- MF:
- C10H22Cl2N2O4
- Structure:
- Chemical Name:
- mitopodozide
- CAS:
- 1508-45-8
- MF:
- C24H30N2O8
- Chemical Name:
- HARRINGTONINE(P)
- Chemical Name:
- Mitoguazone
- Chemical Name:
- Colchiceinamide
- Structure:
- Chemical Name:
- TRIETHYLENEMELAMINE
- CAS:
- 51-18-3
- MF:
- C9H12N6
- Structure:
- Chemical Name:
- INOSINE, PERIODATE OXIDIZED
- CAS:
- 23590-99-0
- MF:
- C10H10N4O5
- Structure:
- Chemical Name:
- trisethyleneiminoquinone
- CAS:
- 68-76-8
- MF:
- C12H13N3O2
- Chemical Name:
- ACTINOMYCIN C
- CAS:
- 8052-16-2
- Chemical Name:
- PODOPHYLLUM BP
- Chemical Name:
- Formylmerphalan
- Chemical Name:
- BETAMERPHALAN