Antineoplastic agents
Hormonal antineoplastic drugs
Antimetabolites, Antineoplastic
Antibiotics anticancer drugs
Antitumor Adjuvant Drugs
Other antineoplastic Drugs
Natural sources of antineoplastic
Alkylating antineoplastic
Tinib Antineoplastic drugs
Idiopathic pulmonary fibrosis(IPF)
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Antineoplastic is a class of medicine to restrain or kill tumor cells in the body. It plays an important role in comprehensive cancer treatment, particularly for disseminated tumor and leukemia that cannot be treated with surgery. Most current antineoplastics work by inhibiting DNA or RNA synthesis, or even damaging the structure of DNA. Antineoplastics can be divided into CCNSA (Cell cycle nonspecific drug) and CCSA (Cell Cycle Specific agents) according to their different effect on tumor cells in different stages of generation cycles. Both of them have a killing effect on bone marrow hematopoietic stem cells and other cells with a short growth cycle, as well as an inhibiting effect on the body's immune response.
Antineoplastic has a wide variety of drugs, which can be divided into following categories:
alkylating agents, such as cyclophosphamide, Glyciphosphoramide, thiotepa, etc.;
antimetabolites, such as methotrexate, mercaptopurine, fluorouracil, hydroxyurea, etc.;
antibiotics, such as dactinomycin, mitomycin C, bleomycin, etc.;
hormones, such as prednisone, testosterone propionate, diethylstilbestrol, etc.;
some botanical drugs, such as Vinblastine, camptothecin, colchicine, etc.;
and other classes, such as procarbazine, propylene imine, Yishuangmalin, etc.
With their enormous diversity and different mechanisms, antineoplastics must be carefully selected for clinical application.
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- Structure:
- Chemical Name:
- Revumenib Citrate
- CAS:
- 2761046-45-9
- MF:
- C32H47FN6O4S.C6H8O7.H2O
- Structure:
- Chemical Name:
- 2-AMINO-5-BROMO-4-HYDROXY-6-PHENYLPYRIMIDINE
- CAS:
- 56741-95-8
- MF:
- C10H8BrN3O
- Structure:
- Chemical Name:
- (1S,3S,7S,10R,11S,12S,16R)-3-[(1E)-2-[2-(Aminomethyl)-4-thiazolyl]-1-methylethenyl]-7,11-dihydroxy-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
- CAS:
- 280578-49-6
- MF:
- C27H42N2O6S
- Structure:
- Chemical Name:
- LEE011
- CAS:
- 1256963-02-6
- MF:
- C22H29ClN8
- Chemical Name:
- Nivolumab
- CAS:
- 946414-94-4
- Structure:
- Chemical Name:
- Fruquintinib
- CAS:
- 1194506-26-7
- MF:
- C21H19N3O5
- Structure:
- Chemical Name:
- Regorafenib
- CAS:
- 755037-03-7
- MF:
- C21H15ClF4N4O3
- Structure:
- Chemical Name:
- Eribulin Mesylate
- CAS:
- 441045-17-6
- MF:
- C41H63NO14S
- Chemical Name:
- HUMAN IL-2
- CAS:
- 110942-02-4
- Structure:
- Chemical Name:
- SM 5887
- CAS:
- 110311-30-3
- MF:
- C25H25NO9.ClH
- Structure:
- Chemical Name:
- Tazemetostat hydrobromide
- CAS:
- 1467052-75-0
- MF:
- C34H45BrN4O4
- Chemical Name:
- Trastuzumab Deruxtecan
- CAS:
- 1826843-81-5
- MF:
- N/A
- Chemical Name:
- Polatuzumab vedotin
- CAS:
- 1313206-42-6
- Structure:
- Chemical Name:
- Nemorubicin
- CAS:
- 108852-90-0
- MF:
- C32H37NO13
- Structure:
- Chemical Name:
- Selumetinib Sulfate
- CAS:
- 943332-08-9
- MF:
- C17H17BrClFN4O7S
- Chemical Name:
- Pembrolizumab
- CAS:
- 1374853-91-4
- Structure:
- Chemical Name:
- MonoMethyl auristatin E
- CAS:
- 474645-27-7
- MF:
- C39H67N5O7
- Structure:
- Chemical Name:
- Savolitinib
- CAS:
- 1313725-88-0
- MF:
- C17H15N9
- Chemical Name:
- Rituximab
- CAS:
- 174722-31-7
- MF:
- C6416H9874N1688O1987S44
- Structure:
- Chemical Name:
- Boronophenylalanine B-10
- CAS:
- 80994-59-8
- MF:
- C9H12BNO4
- Chemical Name:
- Infliximab
- CAS:
- 170277-31-3
- Structure:
- Chemical Name:
- Orelabrutinib
- CAS:
- 1655504-04-3
- MF:
- C26H25N3O3
- Structure:
- Chemical Name:
- AZD7986
- CAS:
- 1802148-05-5
- MF:
- C23 H24 N4 O4
- Structure:
- Chemical Name:
- Carmustine
- CAS:
- 154-93-8
- MF:
- C5H9Cl2N3O2
- Structure:
- Chemical Name:
- Teniposide
- CAS:
- 29767-20-2
- MF:
- C32H32O13S
- Structure:
- Chemical Name:
- Triethylenethiophosphoramide
- CAS:
- 52-24-4
- MF:
- C6H12N3PS
- Chemical Name:
- EPOA
- Structure:
- Chemical Name:
- Lapatinib Ditosylate
- CAS:
- 388082-77-7
- MF:
- C36H34ClFN4O7S2
- Structure:
- Chemical Name:
- Adriamycin
- CAS:
- 23214-92-8
- MF:
- C27H29NO11
- Structure:
- Chemical Name:
- Raltitrexed
- CAS:
- 112887-68-0
- MF:
- C21H22N4O6S
- Structure:
- Chemical Name:
- Mitoxantrone
- CAS:
- 65271-80-9
- MF:
- C22H28N4O6
- Structure:
- Chemical Name:
- 6-Mercaptopurine
- CAS:
- 50-44-2
- MF:
- C5H4N4S
- Structure:
- Chemical Name:
- Mubritinib
- CAS:
- 366017-09-6
- MF:
- C25H23F3N4O2
- Structure:
- Chemical Name:
- 1-beta-D-Arabinofuranosylcytosine hydrochloride
- CAS:
- 69-74-9
- MF:
- C9H14ClN3O5
- Structure:
- Chemical Name:
- Nimustine hydrochloride
- CAS:
- 55661-38-6
- MF:
- C9H14Cl2N6O2
- Structure:
- Chemical Name:
- Melphalan
- CAS:
- 148-82-3
- MF:
- C13H18Cl2N2O2
- Structure:
- Chemical Name:
- Tandutinib
- CAS:
- 387867-13-2
- MF:
- C31H42N6O4
- Structure:
- Chemical Name:
- Tenidap
- CAS:
- 120210-48-2
- MF:
- C14H9ClN2O3S
- Structure:
- Chemical Name:
- Dovitinib
- CAS:
- 915769-50-5
- MF:
- C24H29FN6O5
- Structure:
- Chemical Name:
- 4-(4-METHYLPIPERAZIN-1-YLMETHYL)BENZONITRILE
- CAS:
- 125743-63-7
- MF:
- C13H17N3
- Structure:
- Chemical Name:
- Nilutamide
- CAS:
- 63612-50-0
- MF:
- C12H10F3N3O4
- Structure:
- Chemical Name:
- Vinorelbine
- CAS:
- 71486-22-1
- MF:
- C45H54N4O8
- Structure:
- Chemical Name:
- Epirubicin hydrochloride
- CAS:
- 56390-09-1
- MF:
- C27H30ClNO11
- Structure:
- Chemical Name:
- Lestaurtinib
- CAS:
- 111358-88-4
- MF:
- C26H21N3O4
- Structure:
- Chemical Name:
- Idarubicin hydrochloride
- CAS:
- 57852-57-0
- MF:
- C26H28ClNO9
- Structure:
- Chemical Name:
- N-Desmethyl Imatinib
- CAS:
- 404844-02-6
- MF:
- C28H29N7O
- Structure:
- Chemical Name:
- IDOXIFENE
- CAS:
- 116057-75-1
- MF:
- C28H30INO
- Structure:
- Chemical Name:
- Mitoxantrone hydrochloride
- CAS:
- 70476-82-3
- MF:
- C22H30Cl2N4O6
- Structure:
- Chemical Name:
- MONOCROTALINE
- CAS:
- 315-22-0
- MF:
- C16H23NO6
- Structure:
- Chemical Name:
- Vincristine
- CAS:
- 57-22-7
- MF:
- C46H56N4O10
- Structure:
- Chemical Name:
- Lomustine
- CAS:
- 13010-47-4
- MF:
- C9H16ClN3O2
- Structure:
- Chemical Name:
- Aminoglutethimide
- CAS:
- 125-84-8
- MF:
- C13H16N2O2
- Structure:
- Chemical Name:
- Chlorambucil
- CAS:
- 305-03-3
- MF:
- C14H19Cl2NO2
- Structure:
- Chemical Name:
- NIMUSTINE HYDROCHLORIDE
- CAS:
- 52208-23-8
- MF:
- C9H14Cl2N6O2
- Structure:
- Chemical Name:
- Piperazinone, 3-(2-thienyl)- (9CI)
- CAS:
- 86696-86-8
- MF:
- C8H10N2OS
- Structure:
- Chemical Name:
- N-Boc-N-Desmethyl Imatinib
- CAS:
- 1076199-23-9
- MF:
- C33H37N7O3
- Structure:
- Chemical Name:
- N-DESMETHYL IMATINIB
- CAS:
- 1356565-46-2
- MF:
- C42H47N9O2
- Structure:
- Chemical Name:
- Toremifene
- CAS:
- 89778-26-7
- MF:
- C26H28ClNO
- Structure:
- Chemical Name:
- Daunorubicin
- CAS:
- 20830-81-3
- MF:
- C27H29NO10
- Structure:
- Chemical Name:
- CEPHALOTAXINE
- CAS:
- 24316-19-6
- MF:
- C18H21NO4
- Structure:
- Chemical Name:
- epothilone E
- CAS:
- 201049-37-8
- MF:
- C26H39NO7S
- Structure:
- Chemical Name:
- 4-(4-Methylpiperazin-1-ylmethyl)benzoyl chloride
- CAS:
- 148077-69-4
- MF:
- C13H17ClN2O
- Structure:
- Chemical Name:
- EXO-7-OXABICYCLO[2.2.1]HEPTANE-2,3-DICARBOXYLIC ANHYDRIDE
- CAS:
- 29745-04-8
- MF:
- C8H8O4
- Structure:
- Chemical Name:
- Bendamustine
- CAS:
- 97832-05-8
- MF:
- C16H21Cl2N3O2.HCl
- Structure:
- Chemical Name:
- Estramustine sodium phosphate
- CAS:
- 52205-73-9
- MF:
- C23H33Cl2NNaO6P
- Structure:
- Chemical Name:
- PODOPHYLLOTOXIN
- CAS:
- 4354-76-1
- MF:
- C22H22O8
- Structure:
- Chemical Name:
- FADROZOLE
- CAS:
- 102676-47-1
- MF:
- C14H13N3
- Structure:
- Chemical Name:
- DEMECOLCINE
- CAS:
- 477-30-5
- MF:
- C21H25NO5
- Structure:
- Chemical Name:
- 3',4'-Anhydrovinblastine
- CAS:
- 38390-45-3
- MF:
- C46H56N4O8
- Structure:
- Chemical Name:
- Tilisolol
- CAS:
- 85136-71-6
- MF:
- C17H24N2O3
- Structure:
- Chemical Name:
- Isopropyl-α-[2-methylhydrazino]-p-toluamide
- CAS:
- 671-16-9
- MF:
- C12H19N3O
- Structure:
- Chemical Name:
- PENTOSTATIN
- CAS:
- 53910-25-1
- MF:
- C11H16N4O4
- Structure:
- Chemical Name:
- Telatinib
- CAS:
- 332012-40-5
- MF:
- C20H16ClN5O3
- Structure:
- Chemical Name:
- Bafetinib
- CAS:
- 887650-05-7
- MF:
- C30H31F3N8O
- Structure:
- Chemical Name:
- Idarubicin
- CAS:
- 58957-92-9
- MF:
- C26H27NO9
- Structure:
- Chemical Name:
- Carmofur
- CAS:
- 61422-45-5
- MF:
- C11H16FN3O3
- Structure:
- Chemical Name:
- Catharanthine
- CAS:
- 2468-21-5
- MF:
- C21H24N2O2
- Structure:
- Chemical Name:
- Formestane
- CAS:
- 566-48-3
- MF:
- C19H26O3
- Structure:
- Chemical Name:
- Miltefosine
- CAS:
- 58066-85-6
- MF:
- C21H46NO4P
- Structure:
- Chemical Name:
- Aminopterin
- CAS:
- 54-62-6
- MF:
- C19H20N8O5
- Structure:
- Chemical Name:
- Lonidamine
- CAS:
- 50264-69-2
- MF:
- C15H10Cl2N2O2
- Structure:
- Chemical Name:
- Epothilone C
- CAS:
- 186692-73-9
- MF:
- C26H39NO5S
- Structure:
- Chemical Name:
- Oxaliplatin
- CAS:
- 63121-00-6
- MF:
- C8H12N2O4Pt
- Structure:
- Chemical Name:
- 4-Hydroxy-5-fluorpyrimidine
- CAS:
- 671-35-2
- MF:
- C4H3FN2O
- Structure:
- Chemical Name:
- Pirarubicin
- CAS:
- 72496-41-4
- MF:
- C32H37NO12
- Structure:
- Chemical Name:
- Docetaxel
- CAS:
- 125354-16-7
- MF:
- C45H55NO15
- Structure:
- Chemical Name:
- Octenidine dihydrochloride
- CAS:
- 70775-75-6
- MF:
- C36H64Cl2N4
- Structure:
- Chemical Name:
- Epirubicin
- CAS:
- 56420-45-2
- MF:
- C27H29NO11
- Structure:
- Chemical Name:
- Vindesine sulfate
- CAS:
- 59917-39-4
- MF:
- C43H57N5O11S
- Structure:
- Chemical Name:
- trans-2,3-Dibromo-2-butene-1,4-diol
- CAS:
- 3234-02-4
- MF:
- C4H6Br2O2
- Structure:
- Chemical Name:
- Actinomycin D
- CAS:
- 50-76-0
- MF:
- C62H86N12O16
- Structure:
- Chemical Name:
- MITHRAMYCIN A
- CAS:
- 18378-89-7
- MF:
- C52H76O24
- Structure:
- Chemical Name:
- Estramustine
- CAS:
- 2998-57-4
- MF:
- C23H31Cl2NO3
- Structure:
- Chemical Name:
- Bafetinib
- CAS:
- 859212-16-1
- MF:
- C30H31F3N8O
- Structure:
- Chemical Name:
- Indirubin
- CAS:
- 479-41-4
- MF:
- C16H10N2O2
- Structure:
- Chemical Name:
- Tamoxifen
- CAS:
- 10540-29-1
- MF:
- C26H29NO
- Structure:
- Chemical Name:
- Vincristine sulfate
- CAS:
- 2068-78-2
- MF:
- C46H58N4O14S
- Structure:
- Chemical Name:
- Altretamine
- CAS:
- 645-05-6
- MF:
- C9H18N6
- Structure:
- Chemical Name:
- Fotemustine
- CAS:
- 92118-27-9
- MF:
- C9H19ClN3O5P
- Structure:
- Chemical Name:
- Norcantharidin
- CAS:
- 5442-12-6
- MF:
- C8H8O4