alpha, oMega-Dipropionic acid hexaethylene glycol
alpha, oMega-Dipropionic acid hexaethylene glycol Basic information
- Product Name:
- alpha, oMega-Dipropionic acid hexaethylene glycol
- Synonyms:
-
- alpha, oMega-Dipropionic acid hexaethylene glycol
- HOOC-PEG6-COOH
- α,ω-Dipropionic acid hexaethylene glycol
- 4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid
- Bis-PEG7-acid
- COOH-PEG6-COOH
- COOH-PEG7-COOH
- HOOCCH2CH2O-PEG6-CH2CH2COOH
- CAS:
- 94376-75-7
- MF:
- C18H34O11
- MW:
- 426.46
- Product Categories:
-
- peg
- Mol File:
- 94376-75-7.mol
alpha, oMega-Dipropionic acid hexaethylene glycol Chemical Properties
- storage temp.
- Store at Room Tem.
- form
- Viscous Liquid
- color
- Colorless to light yellow
alpha, oMega-Dipropionic acid hexaethylene glycol Usage And Synthesis
Description
Bis-PEG7-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Biological Activity
Bis-PEG7-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
target
| PEGs
| Cleavable
|