N-Boc-Nortropinone Chemical Properties

Melting point:

70-74 °C

Boiling point:

325.8±35.0 °C(Predicted)

Density 

1.139±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

-1.65±0.20(Predicted)

color 

Off-White

InChI

InChI=1S/C12H19NO3/c1-12(2,3)16-11(15)13-8-4-5-9(13)7-10(14)6-8/h8-9H,4-7H2,1-3H3

InChIKey

MENILFUADYEXNU-DTORHVGOSA-N

SMILES

C12N(C(OC(C)(C)C)=O)C(CC1)CC(=O)C2

CAS DataBase Reference

185099-67-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

41-36/37/38

Safety Statements 

26-39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29399990

MSDS

• Language:English Provider:SigmaAldrich

N-Boc-Nortropinone Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

N-Boc-Nortropinone is a 8-azabicyclo[3.2.1]octane derivative useful as opioid receptor modulator.

Definition

N-Boc-Nortropinone can be used for the preparation of Tropine derivatives. Tropine and its derivatives are a class of important heterocyclic compounds, which are alkaloids present in natural plants. Due to their diverse biological activities, they are widely used in the fields of pesticides, pharmaceuticals, and chemical industries. N-Boc-Nortropinone can also be used to synthesize a new bicyclic vinyl boronate[1].

References

[1] Shyamali Ghosh. “Convenient preparation of aryl-substituted nortropanes by SuzukiMiyaura methodology.” Canadian Journal of Chemistry 29 1 (2006): 555–560.

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