ALPHA-HELICAL CRF (9-41)
ALPHA-HELICAL CRF (9-41) Basic information
- Product Name:
- ALPHA-HELICAL CRF (9-41)
- Synonyms:
-
- CORTICOTROPIN RELEASING FACTOR ANTAGONIST
- H-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-GLU-ALA-GLU-GLN-ALA-ALA-LEU-ASN-ARG-LEU-LEU-LEU-GLU-GLU-ALA-NH2
- ASP-LEU-THR-PHE-HIS-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-ALA-GLU-GLN-ALA-LEU-ASN-ARG-LEU-LEU-GLU-ALA-NH2
- ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-GLU-ALA-GLU-GLN-ALA-ALA-LEU-ASN-ARG-LEU-LEU-LEU-GLU-GLU-ALA-NH2
- ALPHA-HELICAL CORTICOTROPIN RELEASING FA CTOR
- α-helical corticotropin releasing factor fragment (9-41)
- ALPHA-HELICAL CORTICOTROPIN RELEASING FACTOR (9-41)
- ALPHA-HELICAL CORTICOTROPIN RELEASING FACTOR FRAGMENT (9-41)
- CAS:
- 99658-03-4
- MF:
- C22H25IN2O6
- MW:
- 540.34817
- Product Categories:
-
- CRF receptor and related
- Mol File:
- 99658-03-4.mol
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ALPHA-HELICAL CRF (9-41) Chemical Properties
- storage temp.
- −20°C
- form
- powder
- color
- white
MSDS
- Language:English Provider:SigmaAldrich
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ALPHA-HELICAL CRF (9-41) Usage And Synthesis
Biochem/physiol Actions
The corticotropin releasing factor (CRF) antagonist α-helical CRF [9-41] exhibits 10-fold higher affinity for rat CRF2α receptors over human CRF2α receptors. It has been used to elucidate the role of CRF in various physiological systems. In colonic epithelium, it abolishes CRF-induced changes in ion secretion, and significantly inhibits CRF-stimulated conductance. It antagonizes the CRF-induced proinflammatory degranulation of perivascular mast cells that are activated in response to acute psychological stress and CRF secretion.
ALPHA-HELICAL CRF (9-41)Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
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ALPHA-HELICAL CRF (9-41)(99658-03-4)Related Product Information
- a-Helical Corticotropin Releasing Factor (12-41)
- H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2
- ADRENOMEDULLIN (22-52) (HUMAN)
- TERT-BUTYL ISOCYANIDE
- Ferric acetylacetonate
- Benzyl isocyanide
- METHYL ISOCYANOACETATE
- Tosylmethyl isocyanide
- Cupric acetylacetonate
- DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
- N-BUTYLISOCYANIDE
- 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
- Ethyl isocyanoacetate
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
- Aluminum acetylacetonate
- 2,4-PENTANEDIONE, SILVER DERIVATIVE
- COBALT(II) ACETYLACETONATE
- Tris(2,4-pentanedionato)chroMiuM(III)