scutellarin Methylester
scutellarin Methylester Basic information
- Product Name:
- scutellarin Methylester
- Synonyms:
-
- 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid methyl ester
- Breviscapine methyl ester
- Scutellarin Methlester
- scutellarin Methylester
- β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl, methyl ester
- (2S,3S,4S,5R,6S)-Methyl 6-((5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate
- CAS:
- 119262-68-9
- MF:
- C22H20O12
- MW:
- 476.39
- EINECS:
- 300-008-1
- Product Categories:
-
- reagent
- standard substance
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 119262-68-9.mol
scutellarin Methylester Chemical Properties
- Boiling point:
- 804.0±65.0 °C(Predicted)
- Density
- 1.697±0.06 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- pka
- 5.92±0.40(Predicted)
- color
- Yellow
scutellarin Methylester Usage And Synthesis
Effect
The improvement effect of scutellarin methylester on ischemic brain tissue showed that scutellarin methylester can effectively improve the local cerebral blood flow of ischemia-reperfusion in rats, and significantly reduce the degree of ischemic damage to brain tissue. The mechanism may be In order to inhibit cerebral vasospasm caused by protein kinase activation, increase local cerebral blood flow, improve cerebral microcirculation, and reduce inflammatory cell adhesion and infiltration, thereby reducing brain damage.
Mechanism of action
Scutellarin methylester mainly inhibits the formation of thrombus in vitro through three steps, reducing platelet count, inhibiting platelet aggregation function, inhibiting coagulation function in vivo, and promoting fibrinolytic activity, of which the latter two have stronger effects.
Definition
ChEBI: Scutellarin methyl ester is a glucosiduronic acid and a member of flavonoids.
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