2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID Chemical Properties

Boiling point:

460.1±35.0 °C(Predicted)

Density 

1.141±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMF: 5 mg/ml,DMSO: 1 mg/ml,Ethanol: 30 mg/ml

form 

A neat oil

pka

3.39±0.10(Predicted)

color 

Colorless to light yellow

CAS DataBase Reference

462100-06-7

Safety Information

HS Code 

2924190090

2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID Usage And Synthesis

Description

t-Boc-N-amido-PEG3-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.

2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID(462100-06-7)Related Product Information

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• FMoc-NH-PEG9-CH2CH2COOH