Fmoc-Lys-OH hydrochloride Chemical Properties

refractive index 

-11.0 ° (C=1, DMF)

storage temp. 

2-8°C

solubility 

Soluble in dimethyl formamide (0.3g in 2ml).

form 

powder to crystal

color 

White to Almost white

BRN 

8663370

InChIKey

MVMZFAIUUXYFGY-FYZYNONXSA-N

SMILES

C(C1C2=CC=CC=C2C2C=CC=CC1=2)OC(=O)N[C@H](C(=O)O)CCCCN.Cl |&1:18,r|

CAS DataBase Reference

139262-23-0(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29242990

MSDS

• Language:English Provider:SigmaAldrich

Fmoc-Lys-OH hydrochloride Usage And Synthesis

Description

Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also an alkyl chain-based PROTAC linker that can be used to synthesize PROTACs.

Chemical Properties

White solid

Uses

Fmoc-Lys-OH hydrochloride is used as an active pharmaceutical intermediate and in the synthesis of nε-(7-diethylaminocoumarin-3-carboxyl)- and nε-(7-methoxycoumarin-3-carboxyl)-l-fmoc lysine as tools for protease cleavage detection by fluorescence.

Fmoc-Lys-OH hydrochloride(139262-23-0)Related Product Information

• 9-Fluorenylmethyl chloroformate
• L-Fmoc-Aspartic acid alpha-tert-butyl ester
• Glycine hydrochloride
• METHOXYCARBONYLSULFENYL CHLORIDE
• L-Histidine hydrochloride
• CARBONYL SULFIDE
• L-Lysine hydrochloride
• N-(9-Fluorenylmethoxycarbonyloxy)succinimide
• Methoxyammonium chloride
• Fmoc-Asp(OtBu)-OH
• Fmoc-Phe-OH
• Fmoc-Lys(Boc)-OH
• L-Arginine hydrochloride
• Fmoc-N'-methyltrityl-L-lysine
• FMOC-LYS-OH
• 1,1'-Carbonyldiimidazole
• L(+)-Ornithine hydrochloride
• L-Lysine