H2N-PEG24-CH2CH2COOtBu CAS#: 2170987-96-7

H2N-PEG24-CH2CH2COOtBu Basic information

Product Name:

H2N-PEG24-CH2CH2COOtBu

Synonyms:

Amino-PEG24-Boc
Amino-PEG24-t-Bu Ester
4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73-Tetracosaoxapentaheptacontanoic acid, 75-amino-, 1,1-dimethylethyl ester
tert-Butyl 1-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-oate

CAS:

2170987-96-7

MF:

C55H111NO26

MW:

1202.46

Mol File:

2170987-96-7.mol

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H2N-PEG24-CH2CH2COOtBu Chemical Properties

Boiling point:: 953.7±60.0 °C(Predicted)
Density: 1.096±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
pka: 8.74±0.10(Predicted)
form: Solid
color: White to light yellow

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H2N-PEG24-CH2CH2COOtBu Usage And Synthesis

Uses

Amino-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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