HIRUDIN (54-65) (DESULFATED) Chemical Properties

Boiling point:

1913.6±65.0 °C(Predicted)

Density 

1.384±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

pka

3.25±0.10(Predicted)

Sequence

H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OH

LogP

-0.190 (est)

Safety Information

WGK Germany 

3

MSDS

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HIRUDIN (54-65) (DESULFATED) Usage And Synthesis

Chemical Properties

Hirudin is the strongest thrombin retarder so far. It fuses with thrombin to produce a non-covalent nitric oxide synthase with a dissociation constant of the order of 10-12 and a very fast reaction rate. quick. Hirudin and thrombin have strong infectivity, 1μg can neutralize 5μg thrombin, and the molar ratio is 1:1.

Uses

Hirudin is a small protein (polypeptide) composed of 65-66 amino acids. Hirudin has a strong inhibitory effect on thrombin and is the strongest natural specific inhibitor of thrombin found so far.

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