L-Glutamic acid alpha-benzyl ester Chemical Properties

Melting point:

157 °C

Boiling point:

416.0±40.0 °C(Predicted)

Density 

1.245±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

pka

4.21±0.10(Predicted)

form 

powder to crystal

color 

White to Almost white

InChI

InChI=1S/C12H15NO4/c13-10(6-7-11(14)15)12(16)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,14,15)/t10-/m0/s1

InChIKey

HFZKKJHBHCZXTQ-JTQLQIEISA-N

SMILES

C(OCC1=CC=CC=C1)(=O)[C@H](CCC(O)=O)N

CAS DataBase Reference

13030-09-6(CAS DataBase Reference)

Safety Information

HS Code 

2922.42.5000

L-Glutamic acid alpha-benzyl ester Usage And Synthesis

Chemical Properties

White solid

Uses

H-Glu-Obzl is a glutamic acid derivative[1].

Synthesis

The general procedure for the synthesis of L-glutamic acid-5-benzyl ester and (S)-4-amino-5-(benzyloxy)-5-oxopentanoic acid from L-glutamic acid and benzyl alcohol was as follows: under typical reaction conditions, 6.8 mmol L-glutamic acid, 10.2 mmol benzyl alcohol (the molar ratio of L-glutamic acid to benzyl alcohol was 1:1.5), and 0.68 mmol CuCl2 were added to a 50 mL single-necked reaction flask. The reaction mixture was stirred at 60 °C for 2 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature, followed by subsequent analysis.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

L-Glutamic acid alpha-benzyl ester(13030-09-6)Related Product Information

• Benzyl formate
• Benzyl chloroformate
• 4-Nitrobenzyl chloroformate
• Benzyl alcohol
• Benzyl isocyanate
• Benzyl nicotinate
• L-Glutamic acid
• Benzyl butyrate
• Benzyl benzoate
• Benzyl salicylate
• Benzyl acetate
• gamma-Benzyl L-glutamate
• Tris(trimethylsilyl)phosphate
• Benzyl chloride
• α-Lipoic Acid
• Glutamic acid
• H-GLU(OBZL)-OBZL HCL
• Cbz-L-Glutamic acid 1-benzyl ester