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Pyridoxal hydrochloride

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Pyridoxal hydrochloride Basic information

Product Name:
Pyridoxal hydrochloride
Synonyms:
  • Pyridoxal hydrochloride, >=98%
  • Pyridoxal hydrochloride(PLC)
  • PYRIDOXAL HCL SIGMA GRADE CRYSTALLIN
  • PYRIDOXAL HYDROCHLORIDE SUITABLE FOR
  • TIMTEC-BB SBB000425
  • PYRIDOXAL HYDROCHLORIDE
  • PL HCL
  • 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehydhydrochloride
CAS:
65-22-5
MF:
C8H10ClNO3
MW:
203.62
EINECS:
200-602-5
Product Categories:
  • Vitamin Derivatives
  • Vitamins
  • Aldehydes
  • Building Blocks
  • C8
  • Carbonyl Compounds
  • Chemical Synthesis
  • Nutrition Research
  • Organic Building Blocks
  • Vitamin B
  • Vitamin B6
  • Companion Products and Reagents
  • Insect Platform
  • Biochemicals and Reagents
  • Cell Culture
  • Fluorescent Labels
  • Fluorescent Probes
  • Labels
  • Other Fluorescent Labels
  • Particles and Stains
  • Serum-free Media
  • and Substrates
  • Cofactors
  • Enzymes
  • Inhibitors
  • Other Cofactors
  • Isolabel
  • Biochemistry
Mol File:
65-22-5.mol
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Pyridoxal hydrochloride Chemical Properties

Melting point:
173 °C (dec.)(lit.)
storage temp. 
−20°C
form 
Powder
color 
White
Water Solubility 
Soluble in water and ethanol.
Sensitive 
Hygroscopic
Merck 
14,7978
BRN 
3656994
InChIKey
FCHXJFJNDJXENQ-UHFFFAOYSA-N
CAS DataBase Reference
65-22-5(CAS DataBase Reference)
EPA Substance Registry System
Pyridoxal hydrochloride (65-22-5)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-22-36-26
WGK Germany 
2
RTECS 
UV1225000
8
TSCA 
Yes
HS Code 
29362500

MSDS

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Pyridoxal hydrochloride Usage And Synthesis

Chemical Properties

White to off-white crystalline powder

Uses

For the labeling of amino acids and their detection in picomolar amounts1; Coenzymes and Cofactors, vol. 1: Vitamin B6, Pyridoxal Phosphate2

Uses

Pyridoxal is one of the three natural forms of vitamin B6, along with pyridoxamine and pyridoxine. All of these forms are converted in the human body into a single biologically active form, Pyridoxal 5-phosphate (P991715). Green plants are a natural source of Pyridoxal, and its deficiency in the human body can lead to serious complications such as epilepsy and seizures.

Definition

ChEBI: A hydrochloride obtained by combining pyridoxal with one molar equivalent of hydrochloric acid.

Safety Profile

Poison by intramuscular, intravenous, and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also ALDEHYDES.

Purification Methods

Dissolve it in water and adjust the pH to 6 with NaOH. Set aside overnight to crystallise. The crystals are washed with cold water, dried in a vacuum desiccator over P2O5 and stored in a brown bottle at room temperature. The free base is then converted to the hydrochloride with one equivalent of HCl. [Fleck & Alberty J Phys Chem 66 1678 1962, Beilstein 21/13 V 44.]

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