1,4-Diaminobutane dihydrochloride
1,4-Diaminobutane dihydrochloride Basic information
- Product Name:
- 1,4-Diaminobutane dihydrochloride
- Synonyms:
-
- DIAMINOBUTANE DIHYDROCHLORIDE
- 1,4-BUTANEDIAMINE DIHYDROCHLORIDE
- 1,4-BUTANEDIAMMONIUM DICHLORIDE
- 1,4-DIAMINOBUTANE 2HCL
- 1,4-Diaminobutane dihydrochloride,1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Putrescine dihydrochloride, Tetramethylenediamine dihydrochloride
- Putrescine dihydrochloride,1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Tetramethylenediamine dihydrochloride
- 1,4-DiaMinobutane dihydrochloride, 99+% 25GR
- Putrescine 2HCl
- CAS:
- 333-93-7
- MF:
- C4H14Cl2N2
- MW:
- 161.07
- EINECS:
- 206-375-9
- Product Categories:
-
- Heterocyclic Compounds
- antibiotic
- Mol File:
- 333-93-7.mol
1,4-Diaminobutane dihydrochloride Chemical Properties
- Melting point:
- 280 °C (dec.)(lit.)
- Boiling point:
- 265.47°C (rough estimate)
- Density
- 1.2524 (rough estimate)
- refractive index
- 1.6300 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- H2O: 100 mg/mL
- form
- powder
- color
- White
- Water Solubility
- almost transparency
- Sensitive
- Hygroscopic
- Merck
- 14,7947
- BRN
- 3906680
- Stability:
- Stable, but hygroscopic. Substances to be avoided: strong oxidizing agents. Combustible.
- InChIKey
- XXWCODXIQWIHQN-UHFFFAOYSA-N
- CAS DataBase Reference
- 333-93-7(CAS DataBase Reference)
- EPA Substance Registry System
- 1,4-Diaminobutane dihydrochloride (333-93-7)
Safety Information
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- EJ7280000
- TSCA
- Yes
- HS Code
- 29212900
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
1,4-Diaminobutane dihydrochloride Usage And Synthesis
Chemical Properties
white powder
Uses
Putrescine dihydrochloride has been used as medium component in F-12 + GlutaMax medium for mice ganglia culture, retinal ganglion cell culture and in HCT116 colon carcinoma cells for ornithine decarboxylase (ODC) assay.
General Description
Putrescine is an end product of fatty acid metabolism in dead tissues. It is a volatile diamine with pungent odour. It is synthesized by the decarboxylation of ornithine in the presence of enzyme, ornithine decarboxylase. Molecular docking studies reveal the binding of putrescine to human receptors called the trace amine-associated receptors (TAAR6 and TAAR8), present in olfactory epithelium.
Biochem/physiol Actions
Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.
Purification Methods
Crystallise the salt from EtOH/H2O. [Beilstein 4 IV 1284.]
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