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ChemicalBook >  Product Catalog >  Organic Chemistry >  Amides >  Acyclic polyamines and their derivatives >  1,4-Diaminobutane dihydrochloride

1,4-Diaminobutane dihydrochloride

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1,4-Diaminobutane dihydrochloride Basic information

Product Name:
1,4-Diaminobutane dihydrochloride
Synonyms:
  • DIAMINOBUTANE DIHYDROCHLORIDE
  • 1,4-BUTANEDIAMINE DIHYDROCHLORIDE
  • 1,4-BUTANEDIAMMONIUM DICHLORIDE
  • 1,4-DIAMINOBUTANE 2HCL
  • 1,4-Diaminobutane dihydrochloride,1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Putrescine dihydrochloride, Tetramethylenediamine dihydrochloride
  • Putrescine dihydrochloride,1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Tetramethylenediamine dihydrochloride
  • 1,4-DiaMinobutane dihydrochloride, 99+% 25GR
  • Putrescine 2HCl
CAS:
333-93-7
MF:
C4H14Cl2N2
MW:
161.07
EINECS:
206-375-9
Product Categories:
  • Heterocyclic Compounds
  • antibiotic
Mol File:
333-93-7.mol
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1,4-Diaminobutane dihydrochloride Chemical Properties

Melting point:
280 °C (dec.)(lit.)
Boiling point:
265.47°C (rough estimate)
Density 
1.2524 (rough estimate)
refractive index 
1.6300 (estimate)
storage temp. 
Store below +30°C.
solubility 
H2O: 100 mg/mL
form 
powder
color 
White
Water Solubility 
almost transparency
Sensitive 
Hygroscopic
Merck 
14,7947
BRN 
3906680
Stability:
Stable, but hygroscopic. Substances to be avoided: strong oxidizing agents. Combustible.
InChIKey
XXWCODXIQWIHQN-UHFFFAOYSA-N
CAS DataBase Reference
333-93-7(CAS DataBase Reference)
EPA Substance Registry System
1,4-Diaminobutane dihydrochloride (333-93-7)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
EJ7280000
TSCA 
Yes
HS Code 
29212900

MSDS

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1,4-Diaminobutane dihydrochloride Usage And Synthesis

Chemical Properties

white powder

Uses

Putrescine dihydrochloride has been used as medium component in F-12 + GlutaMax medium for mice ganglia culture, retinal ganglion cell culture and in HCT116 colon carcinoma cells for ornithine decarboxylase (ODC) assay.

General Description

Putrescine is an end product of fatty acid metabolism in dead tissues. It is a volatile diamine with pungent odour. It is synthesized by the decarboxylation of ornithine in the presence of enzyme, ornithine decarboxylase. Molecular docking studies reveal the binding of putrescine to human receptors called the trace amine-associated receptors (TAAR6 and TAAR8), present in olfactory epithelium.

Biochem/physiol Actions

Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.

Purification Methods

Crystallise the salt from EtOH/H2O. [Beilstein 4 IV 1284.]

1,4-Diaminobutane dihydrochlorideSupplier

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