Basic information Safety Supplier Related

VUN65671

Basic information Safety Supplier Related

VUN65671 Basic information

Product Name:
VUN65671
Synonyms:
  • VUN65671
  • EBOV/MARV-IN-1
  • Ebola and Marburg Entry Inhibitor
  • MARV,EBOV,virus,Filovirus,inhibit,Inhibitor,VUN-65671,VUN65671,Ebola,Marburg
  • N-(4-(4-Methylpiperidin-1-yl)-3-(trifluoromethyl)phenyl)-4-(morpholinomethyl)benzamide
  • Benzamide, N-[4-(4-methyl-1-piperidinyl)-3-(trifluoromethyl)phenyl]-4-(4-morpholinylmethyl)-
CAS:
2479465-67-1
MF:
C25H30F3N3O2
MW:
461.52
Mol File:
2479465-67-1.mol
More
Less

VUN65671 Chemical Properties

Boiling point:
505.0±50.0 °C(Predicted)
Density 
1.242±0.06 g/cm3(Predicted)
form 
Solid
pka
12.89±0.70(Predicted)
color 
White to off-white
More
Less

VUN65671 Usage And Synthesis

Uses

EBOV/MARV-IN-1 is a potent inhibitor of Ebola virus (EBOV) and Marburg virus (MARV), with broad-spectrum activity (EC50=0.31, and 0.82 μM, respectively) and low cytotoxicity (SI>100) in HeLa cells[1].

IC 50

EBOV; MARV

References

[1] Gaisina IN, et, al. Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections. J Med Chem. 2020 Jul 9;63(13):7211-7225. DOI:10.1021/acs.jmedchem.0c00463

VUN65671Supplier

Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Email
3008007409@qq.com
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Email
Sales@ATKchemical.com
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Email
sales@invivochem.cn
Shanghai Dongyang Biotechnology Co., Ltd.
Tel
0512-0512-13601744364 13601744364
Email
chemsharker@126.com
More
Less

VUN65671(2479465-67-1)Related Product Information