2,3-Dichloropyridine Chemical Properties

Melting point:

64-67 °C (lit.)

Boiling point:

242.42°C (rough estimate)

Density 

1.5159 (rough estimate)

refractive index 

1.5500 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

form 

Crystalline Powder

pka

-0.63±0.10(Predicted)

color 

White to slightly beige

Water Solubility 

slightly soluble

BRN 

109811

InChI

InChI=1S/C5H3Cl2N/c6-4-2-1-3-8-5(4)7/h1-3H

InChIKey

MAKFMOSBBNKPMS-UHFFFAOYSA-N

SMILES

C1(Cl)=NC=CC=C1Cl

CAS DataBase Reference

2402-77-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-22

Safety Statements 

26-36-37/39

RIDADR 

UN2811

WGK Germany 

3

RTECS 

US8050000

Hazard Note 

Irritant

HazardClass 

6.1

HS Code 

29333999

MSDS

• Language:English Provider:2,3-Dichloropyridine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,3-Dichloropyridine Usage And Synthesis

Chemical Properties

White to slightly beige crystalline powder

Uses

2,3-Dichloropyridine is used as a reagent for the preparation of substituted 3-(5-membered heterocycle-carboxamido)pyridine derivatives for treatment of autoimmune and inflammatory diseases. Also in the synthesis, crystal structure and biological activity of novel anthranilic Diamide insecticide with propargyl ether.

Synthesis

2,3-dichloropyridine is synthesized from 2-chloronicotinic acid via amidation, Hofmann degradation, diazotization and Sandmeyer reaction.

Structure and conformation

The complete mol-ecule of 2,3-Dichloropyridine, C5H3Cl2N, is generated by crystallographic twofold symmetry, which forces the pyridine N atom and the opposite C—H group to be statistically disordered. In the crystal, weak aromatic π–π stacking [centroid–centroid separation = 3.805 (4)Å and slippage = 1.704Å] leads to [100] stacks of mol-ecules. Short Cl···Cl contacts [3.334 (3)Å] are also observed. Colourless prisms were grown from ethanol.

2,3-Dichloropyridine(2402-77-9)Related Product Information

• 3-Aminopyridine
• 3-Hydroxypyridine
• Dichloroethane
• 2-Chloro-3-hydroxypyridine
• 2,5-Dichloropyridine
• 1,3-Dichloropropene
• 2-Chloro-5-chloromethylpyridine
• Clopyralid
• Dichloropyridine,98%
• 2,3,5,6-Tetrachloropyridine-4-thiol
• Pentachloropyridine
• 5,6-Dichloronicotinic acid
• Picloram
• 2,3,5-Trichloropyridine
• 3,4,5,6-Tetrachloropyridine-2-carbonitrile
• Triclopyr
• 2,3-Dichloro-5-(trichloromethyl)pyridine
• Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone