Basic information Safety Supplier Related

4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride

Basic information Safety Supplier Related

4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Basic information

Product Name:
4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride
Synonyms:
  • 4-Hydroxy-3,5-dimethoxybenzoic acid 4-[(aminoiminomethyl)amino]butyl ester monohydrochloride
  • Leonurin monohydrochloride
  • 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride
  • SCM-198 hydrochloride
  • SCM-198 HCl
  • Leonurine hydrochloride-RM
  • Leonurine Hydrochloride(P)
  • Leonurine hydrochloride, 10 mM in DMSO
CAS:
24735-18-0
MF:
C14H22ClN3O5
MW:
347.79458
Mol File:
24735-18-0.mol
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4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Chemical Properties

Melting point:
194℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Very Slightly, Heated)
form 
Solid
color 
White to Off-White
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4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Usage And Synthesis

Chemical Properties

White crystalline powder, easily soluble in methanol and water, derived from Leonurus artemisia (Laur.) SY Hu F.

Uses

Leonurine Hydrochloride is an alkaloid plant extract used in the treatment of uterine disorders. Used in the modification of uterine contractions in rats.

in vivo

Leonurine (10 mg/kg/d, p.o.) significantly increases the expressions of PPARγ, LXRα, ABCA1 and ABCG1, and decreases both TG and TC levels in serum of mice[1]. Leonurine hydrochloride (50, 100, 200 mg/kg) improves intracellular lipid accumulation via activating AMPK/SREBP1 pathway, enhances biochemical parameters, reduces hepatic lipoperoxide and increases antioxidant levels in mice[2]. Leonurine (20 mg/kg, p.o.) ameliorates osteoarthritis development in mouse DMM model[3].

4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochlorideSupplier

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