Basic information Safety Supplier Related

ADRENOMEDULLIN (HUMAN)

Basic information Safety Supplier Related

ADRENOMEDULLIN (HUMAN) Basic information

Product Name:
ADRENOMEDULLIN (HUMAN)
Synonyms:
  • H-TYR-ARG-GLN-SER-MET-ASN-ASN-PHE-GLN-GLY-LEU-ARG-SER-PHE-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2
  • H-TYR-ARG-GLN-SER-MET-ASN-ASN-PHE-GLN-GLY-LEU-ARG-SER-PHE-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE: 16-21)
  • ADM 1-52, HUMAN
  • ADRENOMEDULLIN (HUMAN)
  • ADRENOMEDULLIN 1-52, HUMAN
  • humanadrenomedullin
  • adrenomedullin 52 human
  • YRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2 (DISULFIDE BRIDGE: 16-21)
CAS:
148498-78-6
MF:
C264H406N80O77S3
MW:
6028.73324
Product Categories:
  • proteins
  • AdrenomedullinPeptides for Cell Biology
  • Adrenomedullins
  • Hormones
  • Miscellaneous Peptides
  • Other Protein/Peptide Hormones
  • Peptide
Mol File:
148498-78-6.mol
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ADRENOMEDULLIN (HUMAN) Chemical Properties

storage temp. 
-20°C
solubility 
Soluble at 1mg/ml in 1% acetic acid
form 
powder
Sequence
H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2(Disulfide bond)
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Safety Information

WGK Germany 
3
RTECS 
AV6800000
HS Code 
2937190000

MSDS

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ADRENOMEDULLIN (HUMAN) Usage And Synthesis

Uses

Peptide elicits potent hypotensive effect, comparable to calcitonin gene-related peptide. Plays a key role in regulating endometrial angiogenesis.

General Description

Adrenomedullin (ADM) human comprises of 52 amino acids and has amine group in the C-terminal tyrosine residue. It also has a N-terminal ring structure and belongs to calcitonin peptide family. ADM has vasodilatory function and is mapped to human chromosome 11p15.4. Adrenomedullin is highly expressed in endothelial cells. Adrenomedullin controls a majority of cellular processes using cyclic adenosine monophosphate (cAMP) as a messenger. It interacts with calcitonin receptor-like receptor (CRLR) and receptor activity modifying protein 2 (RAMP2). ADM contributes to invasion activity in brain tumor cell lines. ADM signalling plays a key role in tumor progression, especially in acute myeloid leukemia.

Biochem/physiol Actions

Peptide elicits potent hypotensive effect, comparable to calcitonin gene-related peptide. Plays a key role in regulating endometrial angiogenesis.

ADRENOMEDULLIN (HUMAN)Supplier

Alabiochem Tech.Co., Ltd.
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0512-58900862 400-0707518
Email
sales@alabiochem.com
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Email
ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
Email
info@hanhongsci.com
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
Email
shchemsky@sina.com
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Email
info@cellmano.com