3,4,5-Trimethoxyphenol Chemical Properties

Melting point:

145-149 °C

Boiling point:

278.13°C (rough estimate)

Density 

1.2067 (rough estimate)

refractive index 

1.4345 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in chloroform.

form 

Powder and/or Chunks

pka

9.72±0.23(Predicted)

color 

Light yellow to beige to light brown

Sensitive 

Light Sensitive

BRN 

1958573

InChIKey

VTCDZPUMZAZMSB-UHFFFAOYSA-N

CAS DataBase Reference

642-71-7(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 3,4,5-trimethoxy-(642-71-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26

WGK Germany 

3

HS Code 

29095000

MSDS

• Language:English Provider:3,4,5-Trimethoxyphenol
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3,4,5-Trimethoxyphenol Usage And Synthesis

Chemical Properties

light yellow to brown crystalline powder

Uses

3,4,5-Trimethoxyphenol is a useful synthetic intermediate in the synthesis of Thymonin (T413210); a flavonoid compound with potential antioxidant activity against peroxyl radicals.

Definition

ChEBI: A member of the class of phenols that is phenol substituted by methoxy groups at positions 3, 4 and 5.

Purification Methods

Recrystallise the phenol from 10 times its weight of H2O (white needles, m 148o). The acetyl derivative crystallises as elongated prisms from EtOH with m 74o. [Chapman et al. J Chem Soc 3028 1927, Shriner et al. J Am Chem Soc 61 2325 1939, Beilstein 6 H 1154, 6 II 1118, 6 III 6656.]

3,4,5-Trimethoxyphenol(642-71-7)Related Product Information

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