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tert-Butyl 4-(bromomethyl)benzoate

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tert-Butyl 4-(bromomethyl)benzoate Basic information

Product Name:
tert-Butyl 4-(bromomethyl)benzoate
Synonyms:
  • 4-(BROMOMETHYL)-BENZOIC ACID, 1,1-DIMETHYLETHYL ESTER
  • TERT-BUTYL P-(BROMOMETHYL) BENZOATE
  • 4-Bromomethyl-benzoic acid tert-butyl ester
  • t-butyl-4-bromomethylbenzoate
  • 1,1-DIMETHYLETHYL 4-(BROMOMETHYL)BENZOATE
  • 4-BROMO METHYL BENZOIC ACID MONO TERT-BUTYL ESTER
  • tert-Butyl 4-(bromomethyl)benzoate
  • 4-Benzoic acid mono tert-butyl ester
CAS:
108052-76-2
MF:
C12H15BrO2
MW:
271.15
EINECS:
691-573-1
Mol File:
108052-76-2.mol
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tert-Butyl 4-(bromomethyl)benzoate Chemical Properties

Melting point:
53-55 °C
Boiling point:
320.9±25.0 °C(Predicted)
Density 
1.313±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:3): .25 mg/ml
form 
A crystalline solid
CAS DataBase Reference
108052-76-2(CAS DataBase Reference)
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Safety Information

HS Code 
2916399090
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tert-Butyl 4-(bromomethyl)benzoate Usage And Synthesis

Synthesis

To a solution of substituted toluene in carbon tetrachloride were added N-bromosuccinimide (1.1 equiv) and 2,2'-azobis(isobutyronitrile) (0.15 equiv). The mixture was refluxed, then filtered and concentrated. The residue was purified by silica gel column chromatography to give tert-Butyl 4-(bromomethyl)benzoate.

tert-Butyl 4-(bromomethyl)benzoate Preparation Products And Raw materials

Raw materials

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