β-Glucuronidase
β-Glucuronidase Basic information
- Product Name:
- β-Glucuronidase
- Synonyms:
-
- beta-d-glucuronidase
- beta-glucuronidas
- beta-glucuronideglucuronohydrolase
- β-d-glucuronide glucuronosohydrolase
- β-glucuronidase from bovine liver
- β-glucuronidase from escherichia coli
- β-glucuronidase from helix pomatia
- β-glucuronidase from patella vulgata (keyhole limpet)
- CAS:
- 9001-45-0
- MF:
- NULL
- MW:
- 0
- EINECS:
- 232-606-8
- Product Categories:
-
- enzyme
- 3.2.x.x Glycosidases
- 3.x.x.x Hydrolases
- Application Index
- Carbohydrate and PTM AnalysisApplication Index
- Carbohydrate hydrolysis&PTM analysis
- Diagnostic and Analytical EnzymesAnalytical Enzymes
- Molluskan SourceEnzyme Class Index
- β-Glucuronidase
- Carbohydrate HydrolysisEnzymes, Inhibitors, and Substrates
- Mol File:
- Mol File
β-Glucuronidase Chemical Properties
- storage temp.
- -20°C
- form
- powder
- color
- yellow-brown
- Merck
- 13,4480
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 42/43
- Safety Statements
- 22-36/37-45-23
- WGK Germany
- 3
- RTECS
- LZ8990000
- F
- 3-10
MSDS
- Language:English Provider:SigmaAldrich
β-Glucuronidase Usage And Synthesis
Uses
β-glucuronidase is used as a reporter gene in GUS assays to monitor gene expression.
Uses
β-Glucuronidase was used in the study of Cer-β-glucuronide synthesis and evaluation of β-glucuronidase(s) from Escherichia coli or intestinal segments to release the head group.
Uses
In the determination of urinary steroids and of steroid conjugates in blood.
General Description
β-Glucuronidase from Escherichia coli is similar to human glucuronidase enzyme and corresponds to molecular weight close to 69-71 kDa and has an pH optimum of 6.5-7.5. It belongs to family-2 glycosyl hydrolase and has active site residues glutamic acid 394, tyrosine 468 and glutamic acid 504.
Biochem/physiol Actions
β-Glucuronidase (GUSB) is a lysosomal enzyme, that degrades glucuronate-containing glycosaminoglycans. β-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations. Absence of β-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain.
β-Glucuronidase Preparation Products And Raw materials
Raw materials
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β-Glucuronidase(9001-45-0)Related Product Information
- β-D-glucosyl crocetin β-1,6-glucosyltransferase
- β-D-galactosyl-(1→4)-L-rhamnose phosphorylase
- β-D-fucosidase
- β-D-glucopyranosyl abscisate β-glucosidase
- Benzyl isocyanide
- Ferric acetylacetonate
- N-BUTYLISOCYANIDE
- Tosylmethyl isocyanide
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
- METHYL ISOCYANOACETATE
- COBALT(II) ACETYLACETONATE
- TERT-BUTYL ISOCYANIDE
- Ethyl isocyanoacetate
- 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
- DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
- Cupric acetylacetonate
- PHENYLSELENOL