Loratadine Impurity I Chemical Properties

Boiling point:

539.3±50.0 °C(Predicted)

Density 

1.283±0.06 g/cm3(Predicted)

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

3.81±0.20(Predicted)

form 

Solid

color 

Off-White to Beige

Stability:

Light Sensitive

Loratadine Impurity I Usage And Synthesis

Uses

Ethyl 4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate is an impurity of loratadine (L469575), which is a nonsedating-type histamine H1-receptor.

Loratadine Impurity I(133330-56-0)Related Product Information

• 4-Hydroxymethyl Loratadine
• 3-[2-(3-Chlorophenyl)ethyl]-2-pyridinecarbonitrile
• 4-chloro-loratadine
• 8-Dechloro-9-chloro Loratadine
• N-Carbethoxy-4-piperidone
• 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol
• N-Methyl Desloratadine
• Loratadine 2-Chloro IMpurity
• 4-(8-Chloro-5,6-dihydro-3-hydroxy-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester
• Loratadine EP Impurity E
• 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-one (Loratadine Impurity)
• (1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone hydrochloride
• 3,5-Lutidine
• Sch 37370
• Loratadine EP IMpurity F
• 2-Hydroxymethyl Loratadine
• Loratadine N-Oxide
• 8-Dechloro-7-chloro Loratadine