4-PYRIDOXIC ACID Chemical Properties

Melting point:

258-261 °C (dec.)(lit.)

Boiling point:

584.5±50.0 °C(Predicted)

Density 

1.480±0.06 g/cm3(Predicted)

storage temp. 

?20°C

pka

0.47±0.25(Predicted)

Merck 

13,8071

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

2

RTECS 

NS1800000

4-PYRIDOXIC ACID Usage And Synthesis

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 4, p. 625, 1967 DOI: 10.1002/jhet.5570040427

Enzyme inhibitor

This oxidized derivative (FW = 171.15 g/mol) of pyridoxal is the chief catabolic product of pyridoxine, pyridoxal, and pyridoxamine degradation; it can be isolated from human urine. The carboxyl group has a pKa value of 5.50 while the phenolic OH has a value of 9.75. 4-Pyridoxic acid has a blue fluorescence which is maximal between pH 3 and 4. Heating 4-pyridoxic acid in 0.5 N acid will convert the metabolite to its lactone, which has an even stronger fluorescence. Target(s): dextransucrase; glucose dehydrogenase; pyridoxal dehydrogenase; and pyridoxaminephosphate oxidase.

4-PYRIDOXIC ACID(82-82-6)Related Product Information

• 3-Pyridinemethanol
• 3-Hydroxypyridine
• 2-Methylisonicotinic acid
• 4-Pyridinecarboxaldehyde
• 3-Hydroxypyridine-4-carboxaldehyde
• 4-Pyridineacetonitrile,3-hydroxy-(9CI)
• 3,4-Lutidine
• 2-FORMYL-5-PICOLINE
• 4-PYRIDOXIC ACID
• 3-HYDROXY-4-METHYLPYRIDINE
• 2,4-DIMETHYL-3-HYDROXYPYRIDINE
• 4-Pyridylcarbinol
• Pyridoxine
• 3-METHYL-4-PYRIDINECARBOXYLIC ACID
• 2,5-Dimethylpyridine
• 2-METHYL-4-HYDROXYMETHYLPYRIDINE
• 3-Hydroxy-2-methylpyridine
• 2-METHYLISONICOTINALDEHYDE