EC 3.1.4.3 Chemical Properties

storage temp. 

-20°C

solubility 

H2O: soluble1.0mg/mL, faintly hazy to hazy

form 

powder

color 

slightly beige

EPA Substance Registry System

Phospholipase C (9001-86-9)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

SZ6116000

F 

3-10

MSDS

• Language:English Provider:SigmaAldrich

EC 3.1.4.3 Usage And Synthesis

Uses

Phospholipase C (PLC) has been used to study adrenoceptor-mediated transmembrane signaling. It is also used to degrade inositol-containing phospholipids. Furthermore, it has been used to study 9E3 gene activation.

Uses

Phospholipase C from Clostridium perfringens has been used as a positive control in sandwich enzyme linked immunosorbent assay (ELISA) and ELISA.

Uses

The enzyme from Sigma has been used in the digestion of phosphatidylserine fraction of Schistosoma mansoni adult worms.

General Description

This product has been enhanced for energy efficiency and waste prevention when used in biodiesel research.

Biochem/physiol Actions

PLC hydrolyzes the phosphate bond on phosphatidylcholine and other glycerophospholipids yielding diacylglycerol. This enzyme also hydrolyzes the phosphate bonds of sphingomyelin, cardiolipin, choline plasmalogen and ceramide phospholipids. Phospholipase C is induced by thrombin and platelet-activating factor, forming 1,2-diacylglycerol and phosphatidic acid.

EC 3.1.4.3(9001-86-9)Related Product Information

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• Ferric acetylacetonate
• N-BUTYLISOCYANIDE
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• Ethyl isocyanoacetate
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• SALCOMINE
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• TERT-BUTYL ISOCYANIDE
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
• PHENYLSELENOL
• METHYL ISOCYANOACETATE
• COBALT(II) ACETYLACETONATE
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• 3-INDOXYL PHOSPHATE DISODIUM SALT