Propargyl-PEG4-sulfonic acid CAS#: 1817735-29-7

Propargyl-PEG4-sulfonic acid Basic information

Product Name:

Propargyl-PEG4-sulfonic acid

Synonyms:

Propargyl-PEG4-sulfonic acid
3,6,9,12-Tetraoxapentadec-14-ynesulfonic acid
3,6,9,12-Tetraoxapentadec-14-yne-1-sulfonic acid

CAS:

1817735-29-7

MF:

C11H20O7S

MW:

296.34

Mol File:

1817735-29-7.mol

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Propargyl-PEG4-sulfonic acid Chemical Properties

Density: 1.245±0.06 g/cm3(Predicted)
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 1.34±0.50(Predicted)
form: Solid
color: White to off-white

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Propargyl-PEG4-sulfonic acid Usage And Synthesis

Description

Propargyl-PEG4-sulfonic acid is heterobifunction reagent that can reacts with azide compounds or biomolecules via copper catalyzed Click Chemistry reactions.

Uses

Propargyl-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-sulfonic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG4-sulfonic acidSupplier

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