ChemicalBook > Product Catalog > Biochemical Engineering > Nucleoside drugs > DMT-2′Fluoro-dU Phosphoramidite
DMT-2′Fluoro-dU Phosphoramidite
DMT-2′Fluoro-dU Phosphoramidite Basic information
- Product Name:
- DMT-2′Fluoro-dU Phosphoramidite
- Synonyms:
-
- 3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-FLUOROOXOLAN
- 2'-Fluoro-5'-O-DMT-2'-deoxyuridine-3'-CE-Phosphoramidite
- 5'-DMT-2'-F-rU Phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite
- 2'-Deoxy-2'-fluoro-5'-O-DMT-Uridine Phosphoramidite
- DMT-2'-F-DU AMIDITE 0.25G, AB, SINGLE
- DMT-2'-F-dU Amidite 0.25g, 89, Single
- 2’-F-rUPhosphoramidite
- CAS:
- 146954-75-8
- MF:
- C39H46FN4O8P
- MW:
- 748.78
- EINECS:
- 2017-001-1
- Product Categories:
-
- Amidite
- Mol File:
- 146954-75-8.mol
More
Less
DMT-2′Fluoro-dU Phosphoramidite Chemical Properties
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- form
- powder
- pka
- 9.39±0.10(Predicted)
- color
- white to off-white
- InChI
- InChI=1/C39H46FN4O8P/c1-26(2)44(27(3)4)53(50-24-10-22-41)52-36-33(51-37(35(36)40)43-23-21-34(45)42-38(43)46)25-49-39(28-11-8-7-9-12-28,29-13-17-31(47-5)18-14-29)30-15-19-32(48-6)20-16-30/h7-9,11-21,23,26-27,33,35-37H,10,24-25H2,1-6H3,(H,42,45,46)/t33-,35-,36-,37-,53?/s3
- InChIKey
- HQHQPAYRJJMYQX-YOKGOYKLNA-N
- SMILES
- N1(C=CC(=O)NC1=O)[C@@H]1O[C@H](COC(C2=CC=CC=C2)(C2C=CC(=CC=2)OC)C2=CC=C(C=C2)OC)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]1F |&1:8,10,36,51,r|
More
Less
DMT-2′Fluoro-dU Phosphoramidite Usage And Synthesis
Uses
5'-O-DMT-2'-F-Deoxyuridine-CE Phosphoramidite (DMT-2′Fluoro-dU Phosphoramidite) is a uridine phosphoramidite consisting of a fluorine in the 2' position, and the compound is used in the synthesis of DNA.
Definition
DMT-2′Fluoro-dU Phosphoramidite is also known as 2'-F-U CE-Phosphoramidite. 2'-F-RNA oligonucleotides adopt an A-form helix on hybridisation to a target. Whereas a hydroxyl group of RNA is a hydrogen bond donor, fluorine appears to be a weak acceptor. These features of 2'-F-RNA oligonucleotides lead to certain interesting properties. For example, it was demonstrated that oligonucleotides hybridise to a RNA oligonucleotide in the following order of increasing stability: DNA < RNA < 2'-OMe-RNA < 2'-F-RNA
DMT-2′Fluoro-dU PhosphoramiditeSupplier
Wuhu Nuowei Chemical Technology Co., Ltd Gold
- Tel
- 0553-8233716 18055326116
- kendoll@cqpharm.com
Nanjing GoodGene Biotechnology Co., Ltd Gold
- Tel
- 13335632219
- 3152731197@qq.com
Hefei Huana Biomedical Technology Co.,Ltd Gold
- Tel
- 17333066501
- shengwen.fang@huanaok.com.cn
Hefei Stongbio Co.,Ltd. Gold
- Tel
- 15555170917
- sales@stongbio.com
Wuhu Huaren Science and Technology Co., Ltd. Gold
- Tel
- 0553-0553-5842013-801 18155347026
- sale@huarensh.com
More
Less
DMT-2′Fluoro-dU Phosphoramidite(146954-75-8)Related Product Information
- 3-Chloropropyltrimethoxysilane
- Doxifluridine
- 1-beta-D-Arabinofuranosyluracil
- Pseudouridine
- 3-Chloropropyltriethoxysilane
- 3-Aminopropyltriethoxysilane
- Floxuridine
- 5-Fluorouridine
- DMT-dG(ib) Phosphoramidite
- DMT-dA(bz) Phosphoramidite
- DMT-2'O-Methyl-rU Phosphoramidite
- DMT-2'O-TBDMS-rA(bz) Phosphoramidite
- DMT-dG(dmf) Phosphoramidite
- 3'-TBDMS-ibu-rG Phosphoramidite
- Ac-rC Phosphoramidite
- Uridine
- DMT-2′Fluoro-dU Phosphoramidite