MARGATOXIN Chemical Properties

storage temp. 

-20°C

form 

Powder

color 

White to off-white

Water Solubility 

Soluble to 0.50 mg/ml in water

Sequence

Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His (Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys36)

Safety Information

Safety Statements 

22

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

MARGATOXIN Usage And Synthesis

Uses

Margatoxin is a highly pure, synthetic, and biologically active peptide toxin.

Uses

Margatoxin, Recombinant is a specific blocker of Kv1.3, Kv1.6 channels.

Uses

Biochemical probe.

Biochem/physiol Actions

Margatoxin is an α-KTx toxin, which is majorly used in ion channel research. It is a 39-amino acid peptide, which is a specific K(V)1.3 channel voltage-dependent K+ channel blocker. Margatoxin is an immunosuppressant that is isolated from the venom of the scorpion Centruroides margaritatus.

in vivo

storage

-20°C

MARGATOXIN(145808-47-5)Related Product Information

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• DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
• Tris(2,4-pentanedionato)chroMiuM(III)
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
• Tosylmethyl isocyanide
• SALCOMINE
• 2,4-PENTANEDIONE, SILVER DERIVATIVE
• 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
• N-BUTYLISOCYANIDE
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
• Ferric acetylacetonate
• Aluminum acetylacetonate
• Cupric acetylacetonate
• METHYL ISOCYANOACETATE
• Benzyl isocyanide
• Ethyl isocyanoacetate
• PHENYLSELENOL
• COBALT(II) ACETYLACETONATE