(S)-(-)-2-Azetidinecarboxylic acid
- Product Name
- (S)-(-)-2-Azetidinecarboxylic acid
- CAS No.
- 2133-34-8
- Chemical Name
- (S)-(-)-2-Azetidinecarboxylic acid
- Synonyms
- (S)-AZETIDINE-2-CARBOXYLIC ACID;H-AZE-OH;L-AZETIDINE-2-CARBOXYLIC ACID;L-H-Aze-OH;H-AZE(2)-OH;(S)-(-)-2-Azetidinec;N,3-Methylene-L-alanine;L-AZETIDINECARBOXYLIC ACID;l-2-azetidinecarboxylicaci;azetidyl-2-carboxylic acid
- CBNumber
- CB0128117
- Molecular Formula
- C4H7NO2
- Formula Weight
- 101.1
- MOL File
- 2133-34-8.mol
(S)-(-)-2-Azetidinecarboxylic acid Property
- Melting point:
- ~215 °C (dec.)
- alpha
- -125 º (c=1, water 25 ºC)
- Boiling point:
- 189.47°C (rough estimate)
- Density
- 1.2245 (rough estimate)
- refractive index
- -122 ° (C=4, H2O)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
- pka
- 2.35±0.20(Predicted)
- form
- Crystalline Powder or Crystals
- color
- White to light beige
- Water Solubility
- 5 g/100 mL
- Merck
- 14,908
- BRN
- 80678
- InChIKey
- IADUEWIQBXOCDZ-VKHMYHEASA-N
- CAS DataBase Reference
- 2133-34-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- RTECS
- CM4310500
- Hazard Note
- Irritant
- HS Code
- 29339900
- Hazardous Substances Data
- 2133-34-8(Hazardous Substances Data)
- Toxicity
- LD50 scu-mus: 1000 mg/kg 85GDA2 8(1),101,82
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A0760
- Product name
- L-Azetidine-2-carboxylic acid
- Purity
- ≥99%
- Packaging
- 50mg
- Price
- $85.9
- Updated
- 2024/03/01
- Product number
- A0760
- Product name
- L-Azetidine-2-carboxylic acid
- Purity
- ≥99%
- Packaging
- 1g
- Price
- $711
- Updated
- 2024/03/01
- Product number
- A1043
- Product name
- L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $279
- Updated
- 2024/03/01
- Product number
- A1043
- Product name
- L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]
- Purity
- >98.0%(T)
- Packaging
- 100mg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- L09668
- Product name
- (S)-(-)-Azetidine-2-carboxylic acid, 98%
- Packaging
- 250mg
- Price
- $120.65
- Updated
- 2024/03/01
(S)-(-)-2-Azetidinecarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides.
Uses
L-Azetidine-2-carboxylic acid has been used as a:
- collagen synthesis inhibitor
- protein folding antagonist
- as a standard in liquid chromatography-mass spectrometry
Uses
(S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides.
Definition
ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid.
General Description
L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.
Biochem/physiol Actions
Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.
Safety Profile
Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx.
(S)-(-)-2-Azetidinecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (S)-(-)-2-Azetidinecarboxylic acid manufacturers
- Product
- (S)-L-Azetidine-2-carboxylic acid 2133-34-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26
- Product
- (S)-(-)-2-Azetidinecarboxylic acid 2133-34-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-10
- Product
- L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] 2133-34-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27