Trifluoroacetamide
- Product Name
- Trifluoroacetamide
- CAS No.
- 354-38-1
- Chemical Name
- Trifluoroacetamide
- Synonyms
- 2,2,2-TRIFLUOROACETAMIDE;Acetamide, 2,2,2-trifluoro-;CF3CONH2;Triflouroacetamide;Three-;TRIFLUOROACETAMIDE;2-TriflouroacetaMide;Three fluoroacetaMide;Trifluoroacetamide98%;2,2,2-Trifluoracetamid
- CBNumber
- CB0291820
- Molecular Formula
- C2H2F3NO
- Formula Weight
- 113.04
- MOL File
- 354-38-1.mol
Trifluoroacetamide Property
- Melting point:
- 65-70 °C (lit.)
- Boiling point:
- 162.5 °C (lit.)
- Density
- 1.4176 (estimate)
- Flash point:
- 162-164°C
- storage temp.
- Store below +30°C.
- solubility
- 460 g/L (20°C)
- pka
- 12.33±0.50(Predicted)
- form
- Crystalline Powder or Crystals
- color
- White to pale yellow or beige
- PH
- 3.6 (460g/l, H2O, 23℃)
- Water Solubility
- 460 g/L (20 ºC)
- BRN
- 1753625
- InChIKey
- NRKYWOKHZRQRJR-UHFFFAOYSA-N
- LogP
- 0.725 at 23℃ and pH4.83
- Dissociation constant
- 0 at 23℃
- CAS DataBase Reference
- 354-38-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Acetamide, 2,2,2-trifluoro-(354-38-1)
- EPA Substance Registry System
- Acetamide, 2,2,2-trifluoro- (354-38-1)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- RIDADR
- 1759
- WGK Germany
- 3
- Hazard Note
- Harmful/Irritant
- TSCA
- T
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29241900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.14690
- Product name
- 2,2,2-Trifluoroacetamide
- Purity
- for synthesis
- Packaging
- 10G
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 8.14690
- Product name
- 2,2,2-Trifluoroacetamide
- Purity
- for synthesis
- Packaging
- 50G
- Price
- $128
- Updated
- 2024/03/01
- Product number
- 144657
- Product name
- Trifluoroacetamide
- Purity
- 97%
- Packaging
- 25g
- Price
- $42.1
- Updated
- 2024/03/01
- Product number
- 144657
- Product name
- Trifluoroacetamide
- Purity
- 97%
- Packaging
- 100g
- Price
- $111
- Updated
- 2024/03/01
- Product number
- T0598
- Product name
- Trifluoroacetamide
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $20
- Updated
- 2024/03/01
Trifluoroacetamide Chemical Properties,Usage,Production
Chemical Properties
white to pale yellow or beige crystalline powder
Uses
2,2,2-Trifluoroacetamide used in a convenient alternative to the Gabriel synthesis of primary amines from halides by N-alkylation followed by cleavage of the readily-hydrolyzed trifluoroacetyl group and for improved N-alkylation under phase-transfer conditions allowing successive alkylation with different alkyl groups.
Application
Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.
Preparation
One-pot synthetic approach to produce trifluoroacetamide has been developed using an electrochemical method with the B12 complex as a catalyst under mild conditions, in open air at room temperature. Thirty examples of trifluoroacetamide were synthesized from 1,1,1-trichloro-2,2,2-trifluoroethane (CFC-113a) in moderate to good yields. This user-friendly strategy is compatible with a broad range of trifluoroacetamide syntheses.
10.1142/S1088424621500292
General Description
Trifluoroacetamide is a good quencher of tryptophan fluorescence.
Trifluoroacetamide Preparation Products And Raw materials
Raw materials
Preparation Products
Trifluoroacetamide Suppliers
- Tel
- --
- Fax
- --
- interchim@interchim.com
- Country
- France
- ProdList
- 6302
- Advantage
- 76
View Lastest Price from Trifluoroacetamide manufacturers
- Product
- Trifluoroacetamide 354-38-1
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-11-29
- Product
- Trifluoroacetamide 354-38-1
- Price
- US $20.60/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5000kg
- Release date
- 2024-08-21
- Product
- Trifluoroacetamide 354-38-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20t
- Release date
- 2024-06-11