Trifluoroacetamide

Product Name: Trifluoroacetamide
CAS No.: 354-38-1
Chemical Name: Trifluoroacetamide
Synonyms: 2,2,2-TRIFLUOROACETAMIDE;Acetamide, 2,2,2-trifluoro-;CF3CONH2;Triflouroacetamide;Three-;TRIFLUOROACETAMIDE;2-TriflouroacetaMide;Three fluoroacetaMide;Trifluoroacetamide98%;2,2,2-Trifluoracetamid
CBNumber: CB0291820
Molecular Formula: C2H2F3NO
Formula Weight: 113.04
MOL File: 354-38-1.mol

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Trifluoroacetamide Property

Melting point:: 65-70 °C (lit.)
Boiling point:: 162.5 °C (lit.)
Density: 1.4176 (estimate)
Flash point:: 162-164°C
storage temp.: Store below +30°C.
solubility: 460 g/L (20°C)
pka: 12.33±0.50(Predicted)
form: Crystalline Powder or Crystals
color: White to pale yellow or beige
PH: 3.6 (460g/l, H2O, 23℃)
Water Solubility: 460 g/L (20 ºC)
BRN: 1753625
InChIKey: NRKYWOKHZRQRJR-UHFFFAOYSA-N
LogP: 0.725 at 23℃ and pH4.83
Dissociation constant: 0 at 23℃
CAS DataBase Reference: 354-38-1(CAS DataBase Reference)
NIST Chemistry Reference: Acetamide, 2,2,2-trifluoro-(354-38-1)
EPA Substance Registry System: Acetamide, 2,2,2-trifluoro- (354-38-1)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
RIDADR: 1759
WGK Germany: 3
Hazard Note: Harmful/Irritant
TSCA: T
HazardClass: 8
PackingGroup: III
HS Code: 29241900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.14690
Product name: 2,2,2-Trifluoroacetamide
Purity: for synthesis
Packaging: 10G
Price: $37
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.14690
Product name: 2,2,2-Trifluoroacetamide
Purity: for synthesis
Packaging: 50G
Price: $128
Updated: 2024/03/01

Sigma-Aldrich

Product number: 144657
Product name: Trifluoroacetamide
Purity: 97%
Packaging: 25g
Price: $42.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 144657
Product name: Trifluoroacetamide
Purity: 97%
Packaging: 100g
Price: $111
Updated: 2024/03/01

TCI Chemical

Product number: T0598
Product name: Trifluoroacetamide
Purity: >98.0%(GC)
Packaging: 25g
Price: $20
Updated: 2024/03/01

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Trifluoroacetamide Chemical Properties,Usage,Production

Chemical Properties

white to pale yellow or beige crystalline powder

Uses

2,2,2-Trifluoroacetamide used in a convenient alternative to the Gabriel synthesis of primary amines from halides by N-alkylation followed by cleavage of the readily-hydrolyzed trifluoroacetyl group and for improved N-alkylation under phase-transfer conditions allowing successive alkylation with different alkyl groups.

Application

Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.

Preparation

One-pot synthetic approach to produce trifluoroacetamide has been developed using an electrochemical method with the B12 complex as a catalyst under mild conditions, in open air at room temperature. Thirty examples of trifluoroacetamide were synthesized from 1,1,1-trichloro-2,2,2-trifluoroethane (CFC-113a) in moderate to good yields. This user-friendly strategy is compatible with a broad range of trifluoroacetamide syntheses.
10.1142/S1088424621500292

General Description

Trifluoroacetamide is a good quencher of tryptophan fluorescence.

Trifluoroacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

5-(CHLOROMETHYL)-2-(TRIFLUOROMETHYL)THIAZOLE (2-(TRIFLUOROMETHYL)THIAZOL-5-YL)METHANOL 2-BROMO-1-(2-(TRIFLUOROMETHYL)THIAZOL-5-YL)ETHANONE ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE 2,2,2-TRIFLUOROETHYLAMINE 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBALDEHYDE

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Trifluoroacetamide Suppliers

Austria 1 Belgium 2 China 360 Europe 4 France 1 Germany 7 India 19 Italy 1 Japan 6 Russia 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 16 United States 53 Global 476

Sinbond Industiral Co., Ltd.

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Cenik Chemicals

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Melrob Ltd (part of Nordmann)

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Apollo Scientific Ltd

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Molekula Limited

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Manchester Organics

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Apollo Scientific Ltd.

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Leancare Ltd.

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MOLEKULA Ltd.

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CARBONE SCIENTIFIC CO.,LTD

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Eurolabs Limited

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Fluorochem Ltd

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Fluorochem Ltd.

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VWR International

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Fulcrum Scientific Ltd.

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MDA Chemicals Ltd.

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View Lastest Price from Trifluoroacetamide manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Trifluoroacetamide 354-38-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-11-29

Hebei Chuanghai Biotechnology Co,.LTD

Product: Trifluoroacetamide 354-38-1
Price: US $20.60/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000kg
Release date: 2024-08-21

Shaanxi Dideu Medichem Co. Ltd

Product: Trifluoroacetamide 354-38-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20t
Release date: 2024-06-11

354-38-1, TrifluoroacetamideRelated Search:

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Three fluoroacetaMide

2,2,2-TRIFLUOROACETAMIDE

TRIFLUOROACETAMIDE

TRIFLUOROACETIC ACID AMIDE

2,2,2-trifluoro-acetamid

CF3CONH2

Triflouroacetamide

TRIFLUOROACETAMIDE 98%

Acetamide, 2,2,2-trifluoro-

2,2,2-TRIFLOUROACETAMIDE

2,2,2-TRIFLOUROACET-AMIDE (TFAA)

Trifluoroacetamide98%

2,2,2-TRIFLOUROACET-AMIDE TFAA 98+%

2,2,2-Trifluoroacetamide (TFAA)

2,2,2-Trifluoroacetamide ,99%

2,2,2-Trifluoroacetamide,97%

2,2,2-trifluoroacetanide

2-TriflouroacetaMide

2,2,2-TRIFLUOROACETAMIDE FOR SYNTHESIS

Three-

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2,2,4-Trifluoroacetamide, 97%+

2,2,4-Trifluoroacetamide

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354-38-1

C2H2F3NO

CF3CONH3

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