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t-Boc-N-amido-PEG1-acid

Product Name
t-Boc-N-amido-PEG1-acid
CAS No.
1260092-44-1
Chemical Name
t-Boc-N-amido-PEG1-acid
Synonyms
3-(2-((tert-Butoxycarbonyl)amino)ethoxy)propanoic acid;Boc-NH-PEG1-COOH;NH-PEG1-CH2CH2COOH;Boc-PEG1-CH2CH2COOH;Boc-N-amido-PEG1-acid;Boc-NH-PEG1-CH2CH2COOH;t-Boc-N-amido-PEG1-acid;t-Boc-N-amido-PEG1-CH2COOH;t-Boc-N-amido-PEG1-acid t-Boc;t-boc-N-amido-PEG1-propionic acid
CBNumber
CB03062663
Molecular Formula
C10H19NO5
Formula Weight
233.26
MOL File
1260092-44-1.mol
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t-Boc-N-amido-PEG1-acid Property

Boiling point:
385.0±27.0 °C(Predicted)
Density 
1.127±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.29±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B671343
Product name
Boc-NH-PEG1-CH2CH2COOH
Packaging
10mg
Price
$45
Updated
2021/12/16
BroadPharm
Product number
BP-20910
Product name
t-Boc-N-amido-PEG1-acid
Purity
98%
Packaging
1g
Price
$200
Updated
2021/12/16
Apolloscientific
Product number
BIPG1799
Product name
t-Boc-N-amido-PEG1-acid
Packaging
500mg
Price
$410
Updated
2021/12/16
AK Scientific
Product number
0262DB
Product name
3-(2-((Tert-butoxycarbonyl)amino)ethoxy)propanoicacid
Packaging
5g
Price
$531
Updated
2021/12/16
BroadPharm
Product number
BP-20910
Product name
t-Boc-N-amido-PEG1-acid
Purity
98%
Packaging
5G
Price
$625
Updated
2021/12/16
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t-Boc-N-amido-PEG1-acid Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG1-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Biological Activity

Boc-NH-PEG1-CH2CH2COOH is a cleavable ADC linker containing 1 unit PEG, and also a PROTAC linker, belonging to the PEG and Alkyl/ether classes, which can be used for the synthesis of antibody-drug conjugates (ADC) and PROTACs .

target

PEGs

Alkyl/ether

Cleavable

t-Boc-N-amido-PEG1-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-amido-PEG1-acid Suppliers

China 90 India 2 United Kingdom 1 United States 8 Global 101
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from t-Boc-N-amido-PEG1-acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
t-Boc-N-amido-PEG1-acid 1260092-44-1
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-25

1260092-44-1, t-Boc-N-amido-PEG1-acidRelated Search:

Ethylene glycol diacetate Azido-PEG4-NHBoc O-(2-Aminoethyl)-O'-[2-(Boc-amino)ethyl]polyethylene glycol 3000 t-Boc-N-amido-PEG2-NHS ester t-Boc-N-Amido-PEG2-Propargyl O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000 tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate t-boc-N-amido-PEG4-NHS ester Z-8-aMino-3,6-dioxaoctanoic acid t-Boc-N-amido-PEG5-acid Boc-9-AMino-4,7-Dioxanonanoic acid 5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) t-Boc-N-amido-PEG2-acid 2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID t-Boc-Aminoxy-PEG3-Azide t-Boc-N-Amido-PEG4-Azide t-Boc-Aminoxy-PEG4-alcohol

  • t-Boc-N-amido-PEG1-acid
  • Boc-N-amido-PEG1-acid
  • t-boc-N-amido-PEG1-propionic acid
  • Boc-NH-PEG1-CH2CH2COOH
  • 3-[2-(Boc-amino)ethoxy]propanoic acid
  • 3-(2-T-BOC-AMINOETHOXY)PROPANOIC ACID
  • Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-
  • 3-(2-((tert-Butoxycarbonyl)amino)ethoxy)propanoic acid
  • Boc-NH-PEG1-COOH
  • t-Boc-N-amido-PEG1-CH2COOH
  • 3-[2-(tert-Butoxycarbonylamino)ethoxy]propionic acid
  • Boc-PEG1-CH2CH2COOH
  • t-Boc-N-amido-PEG1-acid t-Boc
  • NH-PEG1-CH2CH2COOH
  • 3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid
  • 3-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]propanoic acid
  • 1260092-44-1
  • peg