BMS-986205

Product Name: BMS-986205
CAS No.: 1923833-60-6
Chemical Name: BMS-986205
Synonyms: Linrodostat;CS-2743;F001287;F-001287;BMS-986205;BMS 986205;BMS986205;BMS-986205(Linrodostat);Linrodostat（BMS-986205）;LINRODOSTAT;BMS 986205;BMS986205;(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
CBNumber: CB03339862
Molecular Formula: C24H24ClFN2O
Formula Weight: 410.91
MOL File: 1923833-60-6.mol

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BMS-986205 Property

Boiling point:: 606.8±45.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:42.0(Max Conc. mg/mL);73.75(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);175.59(Max Conc. mM)
form: Solid
pka: 13.80±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B596415
Product name: BMS-986205
Packaging: 10mg
Price: $1890
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BB165429
Product name: BMS 986205
Packaging: 50mg
Price: $507.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BB165429
Product name: BMS 986205
Packaging: 10mg
Price: $145
Updated: 2021/12/16

ChemScene

Product number: CS-0021719
Product name: Linrodostat
Purity: 99.92%
Packaging: 5mg
Price: $156
Updated: 2021/12/16

ChemScene

Product number: CS-0021719
Product name: Linrodostat
Purity: 99.92%
Packaging: 10mg
Price: $288
Updated: 2021/12/16

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BMS-986205 Chemical Properties,Usage,Production

Biological Activity

Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.

Description

BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities.

Uses

BMS-986205 is a compound being studied for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders.

BMS-986205 Preparation Products And Raw materials

Raw materials

Preparation Products

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BMS-986205 Suppliers

China 89 India 1 United States 6 USA 1 Global 97

Shanghai Taibao Pharmaceutical Technology Co., Ltd.

Tel: 13816752554
Email: 1745533547@qq.com
Country: China
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Wuhan Jingkangen Biomedical Technology Co., Ltd

Tel: 13720134139 13720134139
Email: orders@jknbiochem.com
Country: China
ProdList: 5821
Advantage: 58

Shanghai jerryxing Biomedical Technology Co., Ltd

Tel: 17721492509
Email: 643638326@qq.com
Country: China
ProdList: 5345
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Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
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Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 18017383231 18017383231
Fax: qq：2817624287
Email: lyh_antaeus@163.com
Country: China
ProdList: 9347
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
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DKMbiochem.Co. Ltd

Tel: 15901859516
Fax: 15901859516
Email: sales@DKMbiochem.com
Country: China
ProdList: 344
Advantage: 58

Shanghai AQBioPharma Co., Ltd.

Tel: 13661411401
Fax: 51370935-8011
Email: yinglv.que@aqbiopharma.com.cn
Country: China
ProdList: 2805
Advantage: 58

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View Lastest Price from BMS-986205 manufacturers

Zhejiang J&C Biological Technology Co.,Limited

Product: BMS-986205 1923833-60-6
Price: US $0.00/gram
Min. Order: 1gram
Purity: 99%
Supply Ability: 10kg
Release date: 2022-02-18

1923833-60-6, BMS-986205Related Search:

BMS 303141 BMS813160 2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)- Insulin-like Growth Factor-1 Receptor Inhibitor PD-L1 inhibitor 1 AC480 (BMS-599626) 3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-N-(2-pyridinylmethyl)-5H-benzo[4,5]cyclohepta[1,2-b]pyridine-7-methanesulfonamide 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID Upadacitinib Q-VD-OPh hydrate N-(2-(4'-cyanobiphenyl-4-yl)propyl)propane-2-sulfonaMide H3B-6527 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one Senexin B COH-29 (S)-4-(4-((2-(3,5-diMethylphenyl)pyrrolidin-1-yl)Methyl)phenoxy)-3-fluorobenzaMide Budiodarone tartrate 2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide

BMS-986205

Linrodostat

LINRODOSTAT;BMS 986205;BMS986205

BMS 986205;BMS986205

BMS-986205(Linrodostat)

CS-2743

(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid

Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis-(αR)-

(R)-N-(4-Chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide

Linrodostat（BMS-986205）

cis-(αR)-N-(4-Chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methylcyclohexaneacetamide

cis-(alphaR)-N-(4-Chlorophenyl)-4-(6-fluoro-quinolin-4-yl)-alpha-methylcyclohexaneacetamide

F001287

F-001287

1923833-60-6

923833-60-6

C24H24ClFN2O

API