BMS-986205

Product Name: BMS-986205
CAS No.: 1923833-60-6
Chemical Name: BMS-986205
Synonyms: Linrodostat;CS-2743;F001287;F-001287;BMS-986205;BMS 986205;BMS986205;BMS-986205(Linrodostat);Linrodostat（BMS-986205）;LINRODOSTAT;BMS 986205;BMS986205;(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
CBNumber: CB03339862
Molecular Formula: C24H24ClFN2O
Formula Weight: 410.91
MOL File: 1923833-60-6.mol

More

Less

BMS-986205 Property

Boiling point:: 606.8±45.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:42.0(Max Conc. mg/mL);73.75(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);175.59(Max Conc. mM)
form: Solid
pka: 13.80±0.70(Predicted)
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B596415
Product name: BMS-986205
Packaging: 10mg
Price: $1890
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BB165429
Product name: BMS 986205
Packaging: 50mg
Price: $507.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BB165429
Product name: BMS 986205
Packaging: 10mg
Price: $145
Updated: 2021/12/16

ChemScene

Product number: CS-0021719
Product name: Linrodostat
Purity: 99.92%
Packaging: 5mg
Price: $156
Updated: 2021/12/16

ChemScene

Product number: CS-0021719
Product name: Linrodostat
Purity: 99.92%
Packaging: 10mg
Price: $288
Updated: 2021/12/16

More

Less

BMS-986205 Chemical Properties,Usage,Production

Biological Activity

Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.

Description

BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities.

Uses

BMS-986205 is a compound being studied for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders.

BMS-986205 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BMS-986205 Suppliers

China 90 India 1 United States 6 USA 1 Global 98

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38632
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

More

Less

View Lastest Price from BMS-986205 manufacturers

Zhejiang J&C Biological Technology Co.,Limited

Product: BMS-986205 1923833-60-6
Price: US $0.00/gram
Min. Order: 1gram
Purity: 99%
Supply Ability: 10kg
Release date: 2022-02-18

1923833-60-6, BMS-986205Related Search:

BMS 303141 BMS813160 2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)- Insulin-like Growth Factor-1 Receptor Inhibitor PD-L1 inhibitor 1 AC480 (BMS-599626) 3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-N-(2-pyridinylmethyl)-5H-benzo[4,5]cyclohepta[1,2-b]pyridine-7-methanesulfonamide 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID Upadacitinib Q-VD-OPh hydrate N-(2-(4'-cyanobiphenyl-4-yl)propyl)propane-2-sulfonaMide H3B-6527 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one Senexin B COH-29 (S)-4-(4-((2-(3,5-diMethylphenyl)pyrrolidin-1-yl)Methyl)phenoxy)-3-fluorobenzaMide Budiodarone tartrate 2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide

BMS-986205

Linrodostat

LINRODOSTAT;BMS 986205;BMS986205

BMS 986205;BMS986205

BMS-986205(Linrodostat)

CS-2743

(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid

Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis-(αR)-

(R)-N-(4-Chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide

Linrodostat（BMS-986205）

cis-(αR)-N-(4-Chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methylcyclohexaneacetamide

cis-(alphaR)-N-(4-Chlorophenyl)-4-(6-fluoro-quinolin-4-yl)-alpha-methylcyclohexaneacetamide

F001287

F-001287

1923833-60-6

923833-60-6

C24H24ClFN2O

API