ChemicalBook > CAS DataBase List > 4-(Bromomethyl)tetrahydropyran

4-(Bromomethyl)tetrahydropyran

Product Name
4-(Bromomethyl)tetrahydropyran
CAS No.
125552-89-8
Chemical Name
4-(Bromomethyl)tetrahydropyran
Synonyms
4-(broMoMethyl)oxane;4-bromomethytetrahydropyran;4-(BroMoMethyl)tetrahydro...;4-BROMOMETHYLTETRAHYDROPYRAN;4-(Bromomethyl)tetrahydropyrane;4-Bromomethyltetrahydropyran, 96%;4-(Bromomethyl)tetrahydropyran ,97%;4-(BROMOMETHYL)-TETRAHYDRO-2H-PYRAN;2H-Pyran, 4-(broMoMethyl)tetrahydro-;Tetrahydro-2H-pyran-4-yl-MethylbroMide
CBNumber
CB0436966
Molecular Formula
C6H11BrO
Formula Weight
179.05
MOL File
125552-89-8.mol
More
Less

4-(Bromomethyl)tetrahydropyran Property

Boiling point:
88 °C
Density 
1.359±0.06 g/cm3(Predicted)
refractive index 
1.49
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
liquid
color 
Light beige/brown
InChI
InChI=1S/C6H11BrO/c7-5-6-1-3-8-4-2-6/h6H,1-5H2
InChIKey
LMOOYAKLEOGKJR-UHFFFAOYSA-N
SMILES
C1OCCC(CBr)C1
CAS DataBase Reference
125552-89-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
C,Xn
Risk Statements 
36/37/38-34-22
Safety Statements 
26-36/37/39-45-23
RIDADR 
3265
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
Ⅲ
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
B6596
Product name
4-(Bromomethyl)tetrahydro-2H-pyran
Purity
min. 98.0 %
Packaging
5G
Price
$146
Updated
2025/07/31
TCI Chemical
Product number
B6596
Product name
4-(Bromomethyl)tetrahydro-2H-pyran
Purity
min. 98.0 %
Packaging
25G
Price
$438
Updated
2025/07/31
TRC
Product number
B697768
Product name
4-Bromomethyltetrahydropyran
Packaging
500mg
Price
$65
Updated
2021/12/16
Oakwood
Product number
037029
Product name
4-(Bromomethyl)tetrahydropyran
Purity
95%
Packaging
5g
Price
$70
Updated
2021/12/16
Matrix Scientific
Product number
069250
Product name
4-(Bromomethyl)tetrahydropyran
Purity
97%
Packaging
5g
Price
$71
Updated
2021/12/16
More
Less

4-(Bromomethyl)tetrahydropyran Chemical Properties,Usage,Production

Chemical Properties

Viscous liquid

Uses

4-(Bromomethyl)tetrahydropyran is an important organic synthesis intermediate, widely used in the fields of medicine, pesticides and dyes. It can be used to synthesize a variety of biologically active compounds, such as antibacterial agents, anti-tumor drugs, nervous system drugs and fluorescent dyes. In addition, 4-(Bromomethyl)tetrahydropyran can also be used to synthesize organic pigments and functional materials.

Application

4-(Bromomethyl)tetrahydropyran can be used as an intermediate in the synthesis of compounds with antibacterial activity. For example, it can be used to introduce other functional groups through nucleophilic substitution reactions to construct molecules with antibacterial activity. Certain compounds containing tetrahydropyran rings have been studied for their potential to inhibit bacterial growth and reproduction.

Synthesis

To a solution of Tetrahydropyran-4-methanol and N-bromobutanimide (NBS) in DCM was added PPh3 at 0°C. The reaction mixture was stirred at room temperature for 1–2h. The resulting mixture was washed with water (20mL) and brine (3×20mL). The organic layer was concentrated and the residue was purified by silica gel flash chromatography (eluting with ethyl acetate in petroleum ether 2–5%) to give 4-(Bromomethyl)tetrahydropyran as a colorless oil.

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 896 - 916
[2] Journal of the American Chemical Society, 1950, vol. 72, p. 5512,5514
[3] Justus Liebigs Annalen der Chemie, 1937, vol. 532, p. 80
[4] Chem.Abstr., 1940, p. 4396
[5] Journal of the American Chemical Society, 1993, vol. 115, # 18, p. 8401 - 8408

4-(Bromomethyl)tetrahydropyran Preparation Products And Raw materials

Raw materials

Hexane Benzyltriethylammonium chloride Ethanol Potassium bromide Potassium hydroxide Acetone Sodium Tetrahydro-2H-pyran-4-carboxylic acid Tosyl chloride 2,2'-Dichlorodiethyl ether Tetrahydrofuran Diethyl ether Ethyl acetate Lithium Aluminum Hydride Hydrochloric acid Phosphorus tribromide Diethyl malonate Pyridine

Preparation Products

More
Less

4-(Bromomethyl)tetrahydropyran Suppliers

Austria 1 Belgium 1 China 193 France 1 Germany 4 India 5 United Kingdom 5 United States 25 Global 235
BTC Pharmaceutical CO. Ltd
Tel
15716293042 18862996710
Fax
0513-68015394
Email
15050603958@163.com
Country
China
ProdList
695
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
ZHIWE CHEMTECH CO LTD
Tel
021-20221225 13917446399
Fax
QQ:115820162
Email
zwchem@163.com
Country
China
ProdList
617
Advantage
61
ITIC MEDCHEM(SUZHOU) CO.,LTD.
Tel
0512-68323967 18015559028
Fax
+86-512-69200360
Email
sales@iticmedchem.com
Country
China
ProdList
506
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shangchem Co., Ltd.
Tel
+86-21-68182121
Fax
+86-21-68182121
Country
China
ProdList
882
Advantage
52
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
skychemical Co.Ltd
Tel
021-20958197 20965099
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
1183
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Sheepchem Co., Ltd.
Tel
+86 (21) 6715-7650
Fax
+86 (21) 6715-7651
Email
sheepchem@163.com
Country
China
ProdList
994
Advantage
60
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
PingHeAnKang Pharmaceutical Co., Ltd.
Tel
18086832706
Fax
028-89642128
Email
phakzjtxs@phak.cn
Country
China
ProdList
138
Advantage
58
ChongQing Purel Bio-Pharmaceutical Technology Co., Ltd.
Tel
023-89130144 18523560356
Fax
023-67534737
Email
zhyong1011@163.com
Country
China
ProdList
290
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6874
Advantage
55
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4542
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Shanghai Tombiopharma Chemical Co. Ltd.
Tel
13391076197
Email
tombiopharma@163.com
Country
China
ProdList
4987
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Hangzhou Milestone Pharmtech Co., Ltd.
Tel
0571-82896630 18969958410
Email
sales_hz@milestonepharmtech.com
Country
China
ProdList
4894
Advantage
55
Bellen Chemistry Co., Ltd.
Tel
010-60400365-8001 15910885229
Fax
010-60400361
Email
service@bellenchem.com
Country
China
ProdList
4514
Advantage
60
Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
4053
Advantage
60
Giant chemicals
Tel
028-85434334 18108076537
Fax
QQ：245797092
Email
market@gianthx.com
Country
China
ProdList
4505
Advantage
56
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6468
Advantage
55
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Suzhou Crst Pharmatech Co., Ltd.
Tel
0512-62910395 17751098781
Fax
0512-62910396
Email
sales@crstpharma.com
Country
China
ProdList
499
Advantage
58
Wuhan Chemwish Technology Co.， Ltd
Tel
027-67849912
Fax
027-87531808
Email
sales@chemwish.com
Country
China
ProdList
9148
Advantage
60
Nanjing Chemcn Pharmaceutical Co., Ltd.
Tel
18114022054; 18114022054
Fax
+86-25-58857385
Email
3317707757@qq.com
Country
China
ProdList
301
Advantage
55
skychemical Co.Ltd
Tel
021-20960837,QQ1332204249
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
3341
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
More
Less

View Lastest Price from 4-(Bromomethyl)tetrahydropyran manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-BroMoMethyltetrahydropyran 125552-89-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-22
Shanghai Yongzeng Technology Co.,Ltd
Product
4-(Bromomethyl) tetrahydropyran 125552-89-8
Price
US $1500.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kgs
Release date
2024-09-02
Shaanxi Dideu New Materials Co. Ltd
Product
4-(Bromomethyl)tetrahydropyran 125552-89-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-10

125552-89-8, 4-(Bromomethyl)tetrahydropyranRelated Search:

4-IODOTETRAHYDRO-2H-PYRAN (TETRAHYDRO-2H-PYRAN-4-YL)METHANOL 3,4-Dihydro-2H-pyran TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Tetrahydro-2H-pyran-4-carboxylic acid 4-Aminotetrahydropyran Tetrahydro-4H-pyran-4-one 3,6-dihydro-2H-pyran Methyl tetrahydropyran-4-carboxylate 2-methyloxan-4-one Tetrahydro-4-pyranol 4-BROMO-TETRAHYDROPYRAN 4-BROMOMETHYLTETRAHYDROPYRAN 2-(BROMOMETHYL)TETRAHYDRO-2 H-PYRAN AKOS BBS-00003110 AKOS BBS-00003110 8-(BROMOMETHYL)-1,8-DIMETHYL-3-OXABICYCLO[3.2.1]OCTANE-2,4-DIONE 8-(BROMOMETHYL)-1,8-DIMETHYL-3-OXABICYCLO[3.2.1]OCTANE

  • 4-(BROMOMETHYL)-TETRAHYDRO-2H-PYRAN
  • 4-BROMOMETHYLTETRAHYDROPYRAN
  • 4-(Bromomethyl)tetrahydropyrane
  • 4-(Bromomethyl)tetrahydropyran ,97%
  • 4-(Bromomethyl)tetrahydro-2H-pyran 97%
  • 4-bromomethytetrahydropyran
  • Tetrahydro-2H-pyran-4-yl-MethylbroMide
  • 4-(BroMoMethyl)tetrahydro...
  • (Tetrahydro-2H-pyran-4-yl)methyl bromide, 4-(Bromomethyl)oxane
  • 4-(broMoMethyl)oxane
  • 2H-Pyran, 4-(broMoMethyl)tetrahydro-
  • 1-(Tetrahydro-2H-pyran-4-yl)methylbromide
  • 4-BROMOMETHYLTETRAHYDROPYRAN ISO 9001：2015 REACH
  • 4-Bromomethyltetrahydropyran, 96%
  • 125552-89-8
  • C6H11BrO
  • Heterocyclic Compounds
  • blocks
  • Bromides
  • Heterocycles
  • Halides