ChemicalBook > CAS DataBase List > 4-(Hydroxymethyl)benzoic acid

4-(Hydroxymethyl)benzoic acid

Product Name
4-(Hydroxymethyl)benzoic acid
CAS No.
3006-96-0
Chemical Name
4-(Hydroxymethyl)benzoic acid
Synonyms
HMBA;hb linker;HMBA LINKER;HMBA Novabiochem;RARECHEM AL BO 1443;Eprosartan USP RC E;Carbadox Impurity 3;4-methylolbenzoic acid;4-CARBOXYBENZYL ALCOHOL;Hydroxymethylbenzoicacid
CBNumber
CB1382486
Molecular Formula
C8H8O3
Formula Weight
152.15
MOL File
3006-96-0.mol
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4-(Hydroxymethyl)benzoic acid Property

Melting point:
182-185 °C (lit.)
Boiling point:
140-150 °C(Press: 9 Torr)
Density 
1.314±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
pka
4.16±0.10(Predicted)
form 
Coarse Fibers
color 
White
BRN 
2690023
InChIKey
WWYFPDXEIFBNKE-UHFFFAOYSA-N
LogP
0.930
CAS DataBase Reference
3006-96-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HS Code 
29181990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51042
Product name
HMBA
Purity
Novabiochem?
Packaging
5G
Price
$149
Updated
2024/03/01
Sigma-Aldrich
Product number
8.51042
Product name
HMBA
Purity
Novabiochem?
Packaging
25g
Price
$593
Updated
2024/03/01
Sigma-Aldrich
Product number
382639
Product name
4-(Hydroxymethyl)benzoic acid
Purity
99%
Packaging
1g
Price
$26
Updated
2024/03/01
Sigma-Aldrich
Product number
1238262
Product name
Eprosartan Related Compound E
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
15mg
Price
$511
Updated
2024/03/01
TCI Chemical
Product number
H0769
Product name
4-Hydroxymethylbenzoic Acid
Purity
>98.0%(T)
Packaging
10g
Price
$126
Updated
2024/03/01
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4-(Hydroxymethyl)benzoic acid Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

This linkage reagent for SPPS is essentially acid stable. It is useful in combination with Fmoc-amino acids. Its peptide esters are usually cleaved by basic or nucleophilic reagents, especially by ammonia in the preparation of peptide amides.

Uses

4-(Hydroxymethyl)benzoic Acid (Eprosartan USP Related Compound E) is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive agent.

Uses

4-(Hydroxymethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive age nt.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 1365, 1985 DOI: 10.1021/ja00291a042

4-(Hydroxymethyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Hydroxymethyl)benzoic acid Suppliers

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View Lastest Price from 4-(Hydroxymethyl)benzoic acid manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
4-(Hydroxymethyl)benzoic acid 3006-96-0
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000KG
Release date
2023-08-15
Hebei Guanlang Biotechnology Co., Ltd.
Product
4-(Hydroxymethyl)benzoic acid 3006-96-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2023-01-09
Henan Aochuang Chemical Co.,Ltd.
Product
4-(Hydroxymethyl)benzoic acid 3006-96-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-22

3006-96-0, 4-(Hydroxymethyl)benzoic acidRelated Search:

Tris(hydroxymethyl)nitromethane 2-(Trifluoromethyl)benzoic acid p-Toluic acid 4-Bromomethylbenzoic acid 4-(Aminomethyl)benzoic acid o-Toluic acid m-Toluic acid 4-(Chloromethyl)benzoic acid 4-(Hydroxymethyl)phenoxyacetic acid EPROSARTAN Epalrestat iMpurity α-Methylcinnamaldehyde ethyl 2-((E)-5-((E)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetate (2-CHLORO-ACETYLAMINO)-ACETIC ACID METHYL ESTER 3-(2-THIENYL)PROPIONIC ACID Eprosartan related coMpound C 3-Thiazolidineacetic acid, 4-oxo-2-thioxo-, methyl ester Rhodanine-3-acetic acid

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  • 4-(HYDROXYMETHYL)BENZOIC ACID HMBA LINKER 98%
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  • Eprosartan Impurity 5(Eprosartan USP RC E)
  • Eprosartan related coMpound E
  • EcaMsule Related CoMpound B
  • Eprosartan Related Compound E (15 mg) (4-(hydroxymethyl)benzoic acid)
  • 4-(Hydroxymethyl)benzoic acid≥ 99% (HPLC)
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  • 4-(Hydroxymethyl)benzoicaci
  • Carbadox Impurity 3
  • 3006-96-0
  • HOCH2C6H4CO2H
  • Organic Building Blocks
  • Linkers
  • Combinatrial Chemistry
  • C8
  • Carboxylic Acids
  • Carbonyl Compounds
  • Building Blocks
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Organic acids
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  • Combinatorial Chemistry
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  • Bifunctional CrosslinkersCarbonyl Compounds
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