ChemicalBook > CAS DataBase List > 4-(Hydroxymethyl)benzoic acid
4-(Hydroxymethyl)benzoic acid
- Product Name
- 4-(Hydroxymethyl)benzoic acid
- CAS No.
- 3006-96-0
- Chemical Name
- 4-(Hydroxymethyl)benzoic acid
- Synonyms
- HMBA;hb linker;HMBA LINKER;HMBA Novabiochem;RARECHEM AL BO 1443;Eprosartan USP RC E;Carbadox Impurity 3;4-methylolbenzoic acid;4-CARBOXYBENZYL ALCOHOL;Hydroxymethylbenzoicacid
- CBNumber
- CB1382486
- Molecular Formula
- C8H8O3
- Formula Weight
- 152.15
- MOL File
- 3006-96-0.mol
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4-(Hydroxymethyl)benzoic acid Property
- Melting point:
- 182-185 °C (lit.)
- Boiling point:
- 140-150 °C(Press: 9 Torr)
- Density
- 1.314±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol
- pka
- 4.16±0.10(Predicted)
- form
- Coarse Fibers
- color
- White
- BRN
- 2690023
- InChIKey
- WWYFPDXEIFBNKE-UHFFFAOYSA-N
- LogP
- 0.930
- CAS DataBase Reference
- 3006-96-0(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- HS Code
- 29181990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 8.51042
- Product name
- HMBA
- Purity
- Novabiochem?
- Packaging
- 5G
- Price
- $149
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 8.51042
- Product name
- HMBA
- Purity
- Novabiochem?
- Packaging
- 25g
- Price
- $593
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 382639
- Product name
- 4-(Hydroxymethyl)benzoic acid
- Purity
- 99%
- Packaging
- 1g
- Price
- $26
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 1238262
- Product name
- Eprosartan Related Compound E
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 15mg
- Price
- $511
- Updated
- 2024/03/01
TCI Chemical
- Product number
- H0769
- Product name
- 4-Hydroxymethylbenzoic Acid
- Purity
- >98.0%(T)
- Packaging
- 10g
- Price
- $126
- Updated
- 2024/03/01
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4-(Hydroxymethyl)benzoic acid Chemical Properties,Usage,Production
Chemical Properties
Off-white solid
Uses
This linkage reagent for SPPS is essentially acid stable. It is useful in combination with Fmoc-amino acids. Its peptide esters are usually cleaved by basic or nucleophilic reagents, especially by ammonia in the preparation of peptide amides.
Uses
4-(Hydroxymethyl)benzoic Acid (Eprosartan USP Related Compound E) is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive agent.
Uses
4-(Hydroxymethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive age nt.
Synthesis Reference(s)
Journal of the American Chemical Society, 107, p. 1365, 1985 DOI: 10.1021/ja00291a042
4-(Hydroxymethyl)benzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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4-(Hydroxymethyl)benzoic acid Suppliers
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View Lastest Price from 4-(Hydroxymethyl)benzoic acid manufacturers
Hebei Weibang Biotechnology Co., Ltd
- Product
- 4-(Hydroxymethyl)benzoic acid 3006-96-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2023-01-09
Hebei Mojin Biotechnology Co., Ltd
- Product
- 4-(Hydroxymethyl)benzoic acid 3006-96-0
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5000KG
- Release date
- 2023-08-15
Henan Aochuang Chemical Co.,Ltd.
- Product
- 4-(Hydroxymethyl)benzoic acid 3006-96-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-22
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