DBCO-PEG1-acid

Product Name: DBCO-PEG1-acid
CAS No.: 2228857-38-1
Chemical Name: DBCO-PEG1-acid
Synonyms: DBCO-PEG1-PA;DBCO-PEG1-COOH;DBCO-PEG1-acid
CBNumber: CB14849574
Molecular Formula: C24H24N2O5
Formula Weight: 420.47
MOL File: 2228857-38-1.mol

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DBCO-PEG1-acid Property

Boiling point:: 783.9±60.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: 4.28±0.10(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24016
Product name: DBCO-PEG1-acid
Purity: 98%
Packaging: 100mg
Price: $680
Updated: 2021/12/16

BroadPharm

Product number: BP-24016
Product name: DBCO-PEG1-acid
Purity: 98%
Packaging: 250mg
Price: $1350
Updated: 2021/12/16

BroadPharm

Product number: BP-24016
Product name: DBCO-PEG1-acid
Purity: 98%
Packaging: 500mg
Price: $2025
Updated: 2021/12/16

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DBCO-PEG1-acid Chemical Properties,Usage,Production

Description

DBCO-PEG1-acid is an analog of DBCO-Acid with hydrophilic PEG linker and a DBCO group. The DBCO groups is commonly used for Click Chemistry reactions. The hydrophilic PEG chain allows for increased water solubility of compounds in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

DBCO-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG1-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG1-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG1-acid Suppliers

China 26 United States 4 Global 30

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 50266790 18317173152
Fax: QQ3382968513
Email: Hailey@shsendpharm.com
Country: China
ProdList: 909
Advantage: 55

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80534353 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3828
Advantage: 55

Hunan chemfish Scientific co.,ltd

Tel: 85567275 17507325772
Email: sales06@chemfish.com
Country: China
ProdList: 4984
Advantage: 58

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32469
Advantage: 58

Wuhan Ruilida Biomedical Technology Co., Ltd.

Tel: 18201884268
Email: magean83@163.com
Country: China
ProdList: 2284
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1996
Advantage: 58

Xiamen Sinopeg Biotech Co., Ltd.

Tel: 400-9189898 17359873007
Email: sales@sinopeg.com
Country: China
ProdList: 1000
Advantage: 58

Shanghai Minhan Pharmaceutical Technology Co., Ltd.

Tel: 17612188245
Fax: QQ 2816925681
Email: 2816925681@qq.com
Country: China
ProdList: 9842
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988941452
Fax: QQ：3283937693
Email: YN_research@163.com
Country: China
ProdList: 2998
Advantage: 58

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View Lastest Price from DBCO-PEG1-acid manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: DBCO-PEG1-PA 2228857-38-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2026-02-04

2228857-38-1, DBCO-PEG1-acidRelated Search:

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DBCO-PEG1-acid

DBCO-PEG1-COOH

DBCO-PEG1-PA

2228857-38-1