DBCO-PEG4-NH-Boc

Product Name: DBCO-PEG4-NH-Boc
CAS No.: 1255942-12-1
Chemical Name: DBCO-PEG4-NH-Boc
Synonyms: DBCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-Boc-NH;DBCO-NHCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-t-Boc Amine;5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester;5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester (ACI)
CBNumber: CB23373604
Molecular Formula: C34H45N3O8
Formula Weight: 623.74
MOL File: 1255942-12-1.mol

More

Less

DBCO-PEG4-NH-Boc Property

Boiling point:: 840.5±65.0 °C(Predicted)
Density: 1.21±0.1 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Viscous Liquid
pka: 12.23±0.46(Predicted)
color: Colorless to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-23623
Product name: DBCO-NHCO-PEG4-NH-Boc
Purity: 98%
Packaging: 50mg
Price: $280
Updated: 2021/12/16

More

Less

DBCO-PEG4-NH-Boc Chemical Properties,Usage,Production

Description

DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent. it can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions.

Biological Activity

DBCO-NHCO-PEG4-NH-Boc is a PROTAC linker that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Alkyl/ether

DBCO-PEG4-NH-Boc Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DBCO-PEG4-NH-Boc Suppliers

China 32 United States 5 Global 37

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 50266790 18317173152
Fax: QQ3382968513
Email: Hailey@shsendpharm.com
Country: China
ProdList: 909
Advantage: 55

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32469
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1996
Advantage: 58

Henan Lien Chemical Products Co., Ltd.

Tel: 0371-63357898 15378766539
Email: 535046669@qq.com
Country: China
ProdList: 4907
Advantage: 58

Xiamen Sinopeg Biotech Co., Ltd.

Tel: 400-9189898 17359873007
Email: sales@sinopeg.com
Country: China
ProdList: 1000
Advantage: 58

Shanghai Minhan Pharmaceutical Technology Co., Ltd.

Tel: 17612188245
Fax: QQ 2816925681
Email: 2816925681@qq.com
Country: China
ProdList: 9842
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988941452
Fax: QQ：3283937693
Email: YN_research@163.com
Country: China
ProdList: 2998
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

More

Less

View Lastest Price from DBCO-PEG4-NH-Boc manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: DBCO-NHCO-PEG4-Boc-NH 1255942-12-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2026-02-06

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-NHCO-PEG4-NHBoc 1255942-12-1
Price: US $0.00/mg
Min. Order: 50mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-20

1255942-12-1, DBCO-PEG4-NH-BocRelated Search:

DBCO-PEG4-amine DBCO-PEG1-acid DBCO-PEG6-amine,DBCO-PEG6-NH2 Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester DBCO-PEG2-amine DBCO-PEG4-NH-Boc DBCO-Acid Azadibenzocyclooctyne-Biotin conjugate DBCO-PEG1 DBCO-PEG12-acid

DBCO-PEG4-NH-Boc

DBCO-NHCO-PEG4-NH-Boc

DBCO-NHCO-PEG4-t-Boc Amine

5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester

5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester (ACI)

DBCO-NHCO-PEG4-Boc-NH

1255942-12-1

C34H45N3O8