ChemicalBook > CAS DataBase List > 1-Boc-3-(Amino)azetidine

1-Boc-3-(Amino)azetidine

Uses

Product Name: 1-Boc-3-(Amino)azetidine
CAS No.: 193269-78-2
Chemical Name: 1-Boc-3-(Amino)azetidine
Synonyms: TERT-BUTYL 3-AMINOAZETIDINE-1-CARBOXYLATE;Boc-3-(Amino)azetidine;1-Boc-azetidin-3-amine;1-Boc-3-Aminoazatidine;3-AMINO-1-BOC-AZETIDINE;1-BOC-3-(AMINO)AZETIDINE;1-N-Boc-3-aminoazetidine;3-AMINO-1-N-BOC-AZETIDINE;1-Boc-3-Aminoazetidine Hy;1-Boc-3-aminoazetidine ,97%
CBNumber: CB2131519
Molecular Formula: C8H16N2O2
Formula Weight: 172.22
MOL File: 193269-78-2.mol

Less

1-Boc-3-(Amino)azetidine Property

Boiling point:: 79-81 3mm
Density: 1.1g/ml
refractive index: 1.4650
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: DMSO, Methanol, Water
form: Oil
pka: 8.29±0.20(Predicted)
color: Clear Colourless to Pale Yellow
InChI: InChI=1S/C8H16N2O2/c1-8(2,3)12-7(11)10-4-6(9)5-10/h6H,4-5,9H2,1-3H3
InChIKey: WPGLRFGDZJSQGI-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CC(N)C1
CAS DataBase Reference: 193269-78-2(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 34-51-22
Safety Statements: 26-36-45-36/37/39
RIDADR: 2735
Hazard Note: Irritant
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 29339900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B3706
Product name: tert-Butyl 3-Aminoazetidine-1-carboxylate
Purity: min. 98.0 %
Packaging: 1G
Price: $36
Updated: 2025/07/31

TCI Chemical

Product number: B3706
Product name: tert-Butyl 3-Aminoazetidine-1-carboxylate
Purity: min. 98.0 %
Packaging: 10G
Price: $181
Updated: 2025/07/31

TRC

Product number: B600900
Product name: 1-Boc-3-aminoazetidine
Packaging: 250mg
Price: $120
Updated: 2021/12/16

Usbiological

Product number: 262870
Product name: 1-Boc-3-aminoazetidine
Packaging: 100mg
Price: $383
Updated: 2021/12/16

TRC

Product number: B600900
Product name: 1-Boc-3-aminoazetidine
Packaging: 2.5g
Price: $950
Updated: 2021/12/16

Less

1-Boc-3-(Amino)azetidine Chemical Properties,Usage,Production

Uses

1-Boc-3-(Amino)azetidine are widely used and valued as pharmaceutical intermediates. In recent years, numerous new compounds have been successfully prepared and tested through various functional group modifications, many of which exhibit good pharmaceutical activity. For example, 1-diphenylmethyl-3-aminoazacyclic butane and 1-diphenylmethyl-3-hydroxy-3-aminomethylazacyclic butane have been used in the synthesis of some antibacterial and antidepressant drugs. 1-tert-butoxycarbonyl-3-aminocyclobutane is also an important pharmaceutical intermediate used in the synthesis of IRAK-4 inhibitors.

Chemical Properties

Clear Colourless to Pale Yellow Oil

Synthesis

429672-02-6

193269-78-2

General procedure for the synthesis of tert-butyl 3-aminoazetidine-1-carboxylate from 1-BOC-3-azidoazetidine: tert-butyl 3-azidoazetidine-1-carboxylate (0.420 g, 2.19 mmol) was dissolved in EtOAc (20 mL) and 10% Pd/C (100 mg) was added. The reaction mixture was stirred under hydrogen atmosphere (balloon). After 12 h of reaction, the catalyst was removed by filtration through a diatomaceous earth pad. The filtrate was concentrated in vacuum to give a colorless oily product (1.76 g, 99% yield), which could be used in subsequent reactions without further purification.1H NMR (CDCl3): δ 1.50 (s, 9H).

References

[1] Patent: WO2004/74283, 2004, A1. Location in patent: Page 40
[2] Patent: US2011/166121, 2011, A1. Location in patent: Page/Page column 56
[3] Patent: US2003/229226, 2003, A1. Location in patent: Page 21-22

1-Boc-3-(Amino)azetidine Preparation Products And Raw materials

Raw materials

Xylene 3-Hydroxyazetidine hydrochloride Ethanol N,N-Dimethylformamide Potassium iodide Toluene Di-tert-butyl dicarbonate Hydrazine hydrate Triethylamine Palladium Methanesulfonyl chloride 1,4-Dioxane Imidazole Iodine Ethyl acetate Benzhydrylamine Methanol Dimethyl sulfoxide Cetyltributylphosphonium bromide Epichlorohydrin Triphenylphosphine Potassium phthalimide Citric acid

Preparation Products

Less

1-Boc-3-(Amino)azetidine Suppliers

Austria 1 Canada 2 China 239 Europe 1 France 1 Germany 5 India 5 Japan 1 South Korea 1 Ukraine 2 United Kingdom 11 United States 37 Global 306

BTC Pharmaceutical CO. Ltd

Tel: 15716293042 18862996710
Fax: 0513-68015394
Email: 15050603958@163.com
Country: China
ProdList: 694
Advantage: 55

Anhui Leyong Biotechnology Co.,Ltd

Tel: 15055708011
Email: 2093564781@qq.com
Country: China
ProdList: 381
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Changzhou Huanling Chemical Co., Ltd.

Tel: 0519-89803565 13776850645
Fax: 0519-89803575
Email: info4@huanlingchem.com
Country: China
ProdList: 891
Advantage: 68

Sichuan Guanghan Bio-Tech Co., Ltd

Tel: +86-28-86127071
Fax: +86-28-86127072
Email: info@sino-produce.com
Country: China
ProdList: 406
Advantage: 66

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Boc Chemical Co.,Ltd

Tel: 021-34975603-808 18721111801
Fax: +86-21-34975602-805
Email: sales@bocpharma.com
Country: China
ProdList: 1009
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

ZEROSCHEM.CO.,LTD.

Tel: 10-61256048 13810278579
Fax: +86 10 61256049
Email: sales@zeroschem.com
Country: China
ProdList: 1370
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Chembon Pharmaceutical Co., Ltd.

Tel: 028-84252981
Fax: +86-28-84252965
Email: sales@chembon.com.cn
Country: China
ProdList: 850
Advantage: 64

SpringPharma Tech Co.,Ltd

Tel: +86-25-68710855, +86-25-68710897
Fax: 025-68710856
Email: sales@springpharma.net
Country: China
ProdList: 1261
Advantage: 62

Shanghai Chem-Milestone Co., Ltd

Tel: 021-50273253 13641951838
Fax: +86-21-61294436
Email: chemmilestone@163.com
Country: China
ProdList: 151
Advantage: 62

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Chengdu Pukang Biotechnology Co., Ltd

Tel: +86-028-82550498 +86-19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 497
Advantage: 58

Wuhan Haizheng Industry & Trade Development Co. Ltd

Tel: 027-8866 0053/88660577/88660578
Fax: 027-8899 1911
Country: China
ProdList: 1073
Advantage: 55

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

Shanghai potentpharm CO.,Ltd

Tel: (86) 21 51969655
Fax: (86) 21 51969655， QQ：33109286， 263541193
Country: China
ProdList: 487
Advantage: 22

Candia Thamtech Company Limited

Tel: 0371-86615086 18203638366 0371-86159066 13526786601
Fax: 0371-86159066
Country: China
ProdList: 2015
Advantage: 60

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Sheepchem Co., Ltd.

Tel: +86 (21) 6715-7650
Fax: +86 (21) 6715-7651
Email: sheepchem@163.com
Country: China
ProdList: 994
Advantage: 60

Bsisun HK Imoprt And Export Company Limited

Tel: +86-18068513926
Fax: 0086-519-85153711
Country: China
ProdList: 1277
Advantage: 55

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Suzhou Ryan Pharmachem Technology Co.,Ltd

Tel: 0512-66585217 13962137180
Fax: 0512-82177549
Email: sales@ryanchem.com
Country: China
ProdList: 384
Advantage: 55

Chem-Stone Co.,Ltd.

Tel: 020-82185713,82185709 13418171485
Fax: 020-82185696
Email: sales@chem-stone.com
Country: China
ProdList: 744
Advantage: 56

Chengdu Ying Xi Technology Co., Ltd.

Tel: +86-28-87361500 13880902127
Fax: +86-28-87361500
Email: arcche@163.com
Country: China
ProdList: 46
Advantage: 56

Shanghai ChriChem Co., Ltd.

Tel: 021-54880687
Fax: 021-54880687
Country: China
ProdList: 511
Advantage: 55

Shanghai Huikai Chemical Technology Co., Ltd.

Tel: 021-61995394 18916691159
Email: chemicalsea@163.com
Country: China
ProdList: 1972
Advantage: 58

ShangHai Zexin Chemical Technology Co., Ltd.

Tel: 021-60136491 15901897992
Fax: 021-60136492
Country: China
ProdList: 455
Advantage: 55

CEG Chemical Science&Technology Co., Ltd.

Tel: Mobile:13665161512
Fax: +86-510-68873513
Country: China
ProdList: 1785
Advantage: 58

Chimica Laboratories Co., Ltd

Tel: 0086-573-82585213
Fax: 0086-573-82585233
Email: bai@chimicalabs.com
Country: China
ProdList: 861
Advantage: 64

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Sense Chemicals (Shanghai) Co., Ltd.

Tel: +86 13590492756
Fax: +86 (0)21 57626234
Email: michael.he@sensechemicals.com
Country: China
ProdList: 426
Advantage: 58

Less

View Lastest Price from 1-Boc-3-(Amino)azetidine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1-Boc-3-(Amino)azetidine 193269-78-2
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-25

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1-Boc-3-(Amino)azetidine 193269-78-2
Price: US $10.00-8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-06

Career Henan Chemical Co

Product: 1-Boc-3-(Amino)azetidine 193269-78-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 200KG
Release date: 2018-08-19

193269-78-2, 1-Boc-3-(Amino)azetidineRelated Search:

RESMETHRIN ALTRENOGEST tert-Butyl carbazate Butyl acetate Salbutamol Diethylene glycol monobutyl ether Azetidine Buprofezin 3-Aminophenol BUTYL OLEATE N-Carbobenzyloxyglycine Dibutyl phthalate 6-Aminocaproic acid DOBUTAMINE Glycine Cyhalofop-butyl Tris(hydroxymethyl)aminomethane 3-(4-BROMO-PHENYLAMINO)-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

1-Azetidinecarboxylic acid, 3-amino-, 1,1-dimethylethyl ester

1-Boc-3-aminoazetidine ,97%

1-Boc-azetidin-3-amine

1-tert-Butoxycarbonyl-3-aminoazetidine

tert-Butyl 3-aminoazetidine-1-carboxylate, 3-Amino-1-(tert-butoxycarbonyl)azetidine, 3-Amino-1-(tert-butoxycarbonyl)azetane

Boc-3-(Amino)azetidine

1-Boc-3-Aminoazetidine Hy

1-Boc-3-amino-azetidine HCl

1,1-DiMethylethyl 3-AMinoazetidine-1-carboxylate

3-AMino-1-azetidinecarboxylic Acid 1,1-DiMethylethyl Ester

tert-Butyl 3-AMino-1-azetidinecarboxylate

3-Aminoazetidine,N1-BOCprotected97%

3-aminoazetidine-1-carboxylate

3-AMINO-1-N-BOC-AZETIDINE

3-AMINO-1-BOC-AZETIDINE

3-AMINO-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

3-AMINO-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HYDROCHLORIDE

3-AMINOAZETIDINE, N1-BOC PROTECTED

1-BOC-3-(AMINO)AZETIDINE

1-BOC-3-AMINOAZETIDINE HYDROCHLORIDE

TERT-BUTYL 3-AMINOAZETIDINE-1-CARBOXYLATE

1-N-Boc-3-aminoazetidine

3-amino-1-azetidinecarboxylate

3-Aminoazetidine, N1-BOC protected 97%

1-Boc-3-Aminoazatidine

3-AMINO-1-BOC-AZETIDINE 98%

N-BOC-3-AMINOAZETIDINE HYDROCHLORIDE

ert-butyl3-aminoazetidine-1-carboxylate

4-Isoxazoleethanol,3,10-dimethyl-

1-tert butoxycarbonylazetidine-3-amine

3-Amino-1-(N-BOC)azetidine - [A3070]

193269-78-2

Amines

Azetidine

Heterocyclic Compounds

Ring Systems

Heterocycles

Miscellaneous Reagents

pharmacetical

Heterocycles series